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what any key link opens

psx:substance/mephedrone/value/duration/oral/total@1

valuereferenced by edges — no row of its own

derived from · upstream

feeds · downstream

none recorded

Closure of psx:substance/mephedrone/value/duration/oral/total@1: 1 upstream, 0 downstream.

psx:substance/mephedrone/value/duration/oral/total@1
└─ derived_from  proposal/duration/b8dc0f3b-489c-49db-b3e9-337cb8107504  duration · oral · total

indented by distance from this node, not by parentage

1Provenance card

the boundary, as counts

Sources

4137 with DOI

4 strong · 31 moderate · 6 weak

Compilations

12026-04-20T23:32:24.316Z

pipeline-v5 · prompt hash not recorded — run predates 2026-09

Decisions

78last ruled 2026-06-04

0 awaiting a ruling

Issued documents

42026-10-19T20:32:45.725Z

notice · info card · emergency

Searches

210 with no results

queries and counts on the build

Claims checked

1234 supported

4 supported · 119 not

Correspondence

0received

consent field ships in Phase 4

Edges

365

derivations recorded for this entity

Complete over 41 sources, 1 compilation, and 78 decisions.Not here: the private journal (never).Working material — drafts, discards, unsupported claims — is listed below and readable on the working page.Cite: psychedex.org/substances/mephedrone/archive

2Build

one panel per compilation run

generation run 2026-04-20

80 min completedmodel pipeline-v5plan not recordedrun/5d640c3d…

Selection

results seen108
selected by the model47
consumed as sources41

Verification

claims checked123
supported4
partially supported0
not supported0
inconclusive119
  • record
  • seen / partial
  • working

The model's own caveats

none raised on this run

Reproduce

inputs
41 source keys (listed under Sources)
plan
not recorded — template version, prompt hash and git SHA are written from 2026-09 onward
model
pipeline-v5
streams
none — agent transcripts are persisted from 2026-09 onward
21 searches — query, source, results, what was kept and why
21 searches for this run
#sourcequeryseenkeptrationale
1PubChemmephedrone11Primary chemical identity data for mephedrone
2ClinicalTrials.govmephedrone42Human pharmacology Phase 1 trials directly relevant to mephedrone dosing, abuse liability, and alcohol interactions
3OpenAlexmephedrone 4-methylmethcathinone pharmacology158High-citation landmark papers covering pharmacology, clinical toxicology, and mechanism of action
4PubMedmephedrone toxicity overdose case report adverse effects32Toxicology case reports directly relevant to mephedrone safety
5PubMedmephedrone pharmacology mechanism dopamine serotonin transporter96Core pharmacology papers with binding data and mechanism of action
6PubMedmephedrone dependence addiction abuse potential self-administration11—
7PubMedPMID 21072502, 21810934, 20358417 fetch33—
8PubMedmephedrone human pharmacokinetics metabolism bioavailability21—
9PubMedmephedrone subjective effects human study clinical trial33—
10PubMedmephedrone deaths fatalities post-mortem forensic33—
11ClinicalTrials.govmephedrone42—
12Erowid/WebSearchmephedrone legal status scheduling US UK Germany Australia102—
13WebSearchmephedrone first synthesis 1929 Saem de Burnaga Sanchez history101—
14PubMedmephedrone cardiovascular cardiac effects blood pressure54—
15OpenAlexDOI 10.1111/j.1476-5381.2012.02145.x (Simmler 2012)11—
16PubMedmephedrone pharmacokinetics metabolites nor-mephedrone dihydromephedrone urine22—
17Crossref/verify_doiDOI 10.1007/s13181-011-0193-z11—
18WebSearch/Erowidmephedrone legal status jurisdictions101—
19WebSearchmephedrone SMILES CAS melting point physical properties101—
20PubMedPMID 22778288 serotonin syndrome mephedrone11—
21WebSearchmephedrone tramadol fatal interaction serotonin case report101—
123 claims by section — every cited sentence, checked against its source
safety42 · 4 ok
  • Serotonin syndrome has been documented from mephedrone alonesupported

    Principal substance mephedrone. Became hyperthermic, deteriorated over next hour. Appropriate treatment for serotonin syndrome led to sustained recovery over 15h. bcr.04.2010.2925

  • Claim in safety — inconclusiveinconclusiveworking →

  • Claim in safety — inconclusiveinconclusiveworking →

  • A 22-year-old male presented with tachycardia, diaphoresis, hypertonia, hyperreflexia, clonus, and hyperthermia following mephedrone ingestion; progressive deterioration occurred over the first hour, with sustained recovery over 15 hours under appropriate managementsupported

    22-year-old male presented with tachycardia, diaphoresis, hypertonia, hyper-reflexia and clonus. Principal substance mephedrone. Became hyperthermic, deteriorated over next hour. Appropriate treatment for serotonin syndrome led to sustained recovery over 15h. bcr.04.2010.2925

  • Claim in safety — inconclusiveinconclusiveworking →

  • Claim in safety — inconclusiveinconclusiveworking →

  • Claim in safety — inconclusiveinconclusiveworking →

  • Claim in safety — inconclusiveinconclusiveworking →

  • Claim in safety — inconclusiveinconclusiveworking →

  • Claim in safety — inconclusiveinconclusiveworking →

  • Claim in safety — inconclusiveinconclusiveworking →

  • Claim in safety — inconclusiveinconclusiveworking →

  • Claim in safety — inconclusiveinconclusiveworking →

  • Claim in safety — inconclusiveinconclusiveworking →

  • Claim in safety — inconclusiveinconclusiveworking →

  • Claim in safety — inconclusiveinconclusiveworking →

  • Claim in safety — inconclusiveinconclusiveworking →

  • Claim in safety — inconclusiveinconclusiveworking →

  • Claim in safety — inconclusiveinconclusiveworking →

  • Claim in safety — inconclusiveinconclusiveworking →

  • Claim in safety — inconclusiveinconclusiveworking →

  • Claim in safety — inconclusiveinconclusiveworking →

  • Claim in safety — inconclusiveinconclusiveworking →

  • Claim in safety — inconclusiveinconclusiveworking →

  • Claim in safety — inconclusiveinconclusiveworking →

  • Claim in safety — inconclusiveinconclusiveworking →

  • Claim in safety — inconclusiveinconclusiveworking →

  • Claim in safety — inconclusiveinconclusiveworking →

  • Mephedrone alone can precipitate serotonin syndrome; co-administration with SSRIs, SNRIs, MAOIs, tramadol, lithium, or triptans elevates this risk substantiallysupported

    Principal substance mephedrone. Became hyperthermic, deteriorated over next hour. Appropriate treatment for serotonin syndrome led to sustained recovery over 15h. bcr.04.2010.2925

  • Claim in safety — inconclusiveinconclusiveworking →

  • Claim in safety — inconclusiveinconclusiveworking →

  • Claim in safety — inconclusiveinconclusiveworking →

  • Claim in safety — inconclusiveinconclusiveworking →

  • Claim in safety — inconclusiveinconclusiveworking →

  • Claim in safety — inconclusiveinconclusiveworking →

  • Claim in safety — inconclusiveinconclusiveworking →

  • Claim in safety — inconclusiveinconclusiveworking →

  • Claim in safety — inconclusiveinconclusiveworking →

  • Claim in safety — inconclusiveinconclusiveworking →

  • Mephedrone alone causes serotonin syndrome at recreational doses.supported

    Principal substance mephedrone. Became hyperthermic, deteriorated over next hour. Appropriate treatment for serotonin syndrome led to sustained recovery over 15h. bcr.04.2010.2925

  • Claim in safety — inconclusiveinconclusiveworking →

  • Claim in safety — inconclusiveinconclusiveworking →

pharmacology20 · 0 ok
  • Claim in pharmacology — inconclusiveinconclusiveworking →

  • Claim in pharmacology — inconclusiveinconclusiveworking →

  • Claim in pharmacology — inconclusiveinconclusiveworking →

  • Claim in pharmacology — inconclusiveinconclusiveworking →

  • Claim in pharmacology — inconclusiveinconclusiveworking →

  • Claim in pharmacology — inconclusiveinconclusiveworking →

  • Claim in pharmacology — inconclusiveinconclusiveworking →

  • Claim in pharmacology — inconclusiveinconclusiveworking →

  • Claim in pharmacology — inconclusiveinconclusiveworking →

  • Claim in pharmacology — inconclusiveinconclusiveworking →

  • Claim in pharmacology — inconclusiveinconclusiveworking →

  • Claim in pharmacology — inconclusiveinconclusiveworking →

  • Claim in pharmacology — inconclusiveinconclusiveworking →

  • Claim in pharmacology — inconclusiveinconclusiveworking →

  • Claim in pharmacology — inconclusiveinconclusiveworking →

  • Claim in pharmacology — inconclusiveinconclusiveworking →

  • Claim in pharmacology — inconclusiveinconclusiveworking →

  • Claim in pharmacology — inconclusiveinconclusiveworking →

  • Claim in pharmacology — inconclusiveinconclusiveworking →

  • Claim in pharmacology — inconclusiveinconclusiveworking →

neuroscience16 · 0 ok
  • Claim in neuroscience — inconclusiveinconclusiveworking →

  • Claim in neuroscience — inconclusiveinconclusiveworking →

  • Claim in neuroscience — inconclusiveinconclusiveworking →

  • Claim in neuroscience — inconclusiveinconclusiveworking →

  • Claim in neuroscience — inconclusiveinconclusiveworking →

  • Claim in neuroscience — inconclusiveinconclusiveworking →

  • Claim in neuroscience — inconclusiveinconclusiveworking →

  • Claim in neuroscience — inconclusiveinconclusiveworking →

  • Claim in neuroscience — inconclusiveinconclusiveworking →

  • Claim in neuroscience — inconclusiveinconclusiveworking →

  • Claim in neuroscience — inconclusiveinconclusiveworking →

  • Claim in neuroscience — inconclusiveinconclusiveworking →

  • Claim in neuroscience — inconclusiveinconclusiveworking →

  • Claim in neuroscience — inconclusiveinconclusiveworking →

  • Claim in neuroscience — inconclusiveinconclusiveworking →

  • Claim in neuroscience — inconclusiveinconclusiveworking →

summary14 · 0 ok
  • Claim in summary — inconclusiveinconclusiveworking →

  • Claim in summary — inconclusiveinconclusiveworking →

  • Claim in summary — inconclusiveinconclusiveworking →

  • Claim in summary — inconclusiveinconclusiveworking →

  • Claim in summary — inconclusiveinconclusiveworking →

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  • Claim in summary — inconclusiveinconclusiveworking →

  • Claim in summary — inconclusiveinconclusiveworking →

  • Claim in summary — inconclusiveinconclusiveworking →

  • Claim in summary — inconclusiveinconclusiveworking →

  • Claim in summary — inconclusiveinconclusiveworking →

receptor-pharmacology8 · 0 ok
  • Claim in receptor-pharmacology — inconclusiveinconclusiveworking →

  • Claim in receptor-pharmacology — inconclusiveinconclusiveworking →

  • Claim in receptor-pharmacology — inconclusiveinconclusiveworking →

  • Claim in receptor-pharmacology — inconclusiveinconclusiveworking →

  • Claim in receptor-pharmacology — inconclusiveinconclusiveworking →

  • Claim in receptor-pharmacology — inconclusiveinconclusiveworking →

  • Claim in receptor-pharmacology — inconclusiveinconclusiveworking →

  • Claim in receptor-pharmacology — inconclusiveinconclusiveworking →

pharmacokinetic-detail6 · 0 ok
  • Claim in pharmacokinetic-detail — inconclusiveinconclusiveworking →

  • Claim in pharmacokinetic-detail — inconclusiveinconclusiveworking →

  • Claim in pharmacokinetic-detail — inconclusiveinconclusiveworking →

  • Claim in pharmacokinetic-detail — inconclusiveinconclusiveworking →

  • Claim in pharmacokinetic-detail — inconclusiveinconclusiveworking →

  • Claim in pharmacokinetic-detail — inconclusiveinconclusiveworking →

comparative-pharmacology5 · 0 ok
  • Claim in comparative-pharmacology — inconclusiveinconclusiveworking →

  • Claim in comparative-pharmacology — inconclusiveinconclusiveworking →

  • Claim in comparative-pharmacology — inconclusiveinconclusiveworking →

  • Claim in comparative-pharmacology — inconclusiveinconclusiveworking →

  • Claim in comparative-pharmacology — inconclusiveinconclusiveworking →

history5 · 0 ok
  • Claim in history — inconclusiveinconclusiveworking →

  • Claim in history — inconclusiveinconclusiveworking →

  • Claim in history — inconclusiveinconclusiveworking →

  • Claim in history — inconclusiveinconclusiveworking →

  • Claim in history — inconclusiveinconclusiveworking →

clinical-evidence3 · 0 ok
  • Claim in clinical-evidence — inconclusiveinconclusiveworking →

  • Claim in clinical-evidence — inconclusiveinconclusiveworking →

  • Claim in clinical-evidence — inconclusiveinconclusiveworking →

chemistry2 · 0 ok
  • Claim in chemistry — inconclusiveinconclusiveworking →

  • Claim in chemistry — inconclusiveinconclusiveworking →

effects-overview2 · 0 ok
  • Claim in effects-overview — inconclusiveinconclusiveworking →

  • Claim in effects-overview — inconclusiveinconclusiveworking →

3Sources

41 consumed · sorted by year · feeds = sections resting on it

Sources 1 to 30
yearsourcetierstatusfeeds
2025Chemsex-related deaths in the United Kingdom (2017-2022): A review of the Forensic Toxicology dataTyler M, Ward L, Grosse S · Forensic Science Internationaldoi:10.1016/j.forsciint.2025.112553moderateconsumed2 sections
2024SMILES and physical properties of mephedrone (CID 45266826)PubChem/Chemsrcurl:f0071bcdab06c69fweakconsumedcited only
2023Mephedrone induces partial release at human dopamine transporters but full release at human serotonin transportersMayer FP, Niello M, Bulling S, et al. · Neuropharmacologydoi:10.1016/j.neuropharm.2023.109704moderateconsumed4 sections
2023Neurochemical and Cardiovascular Effects of 4-Chloro Ring-Substituted Synthetic Cathinones in RatsChojnacki MR, Thorndike EB, Partilla JS, et al. · Journal of Pharmacology and Experimental Therapeuticsdoi:10.1124/jpet.122.001478moderateconsumed1 section
2021Acute Pharmacological Effects of Oral and Intranasal Mephedrone: An Observational Study in HumansPapaseit E, Olesti E, Perez-Mana C, et al. · Pharmaceuticalsdoi:10.3390/ph14020100moderateconsumed4 sections
2021Pharmacokinetics of Mephedrone and Its Metabolites in Whole Blood and Plasma after Controlled Intranasal Administration to Healthy Human VolunteersCzerwinska J, Parkin MC, George C, et al. · Journal of Analytical Toxicologydoi:10.1093/jat/bkaa134moderateconsumed1 section
2020Designer drugs: mechanism of action and adverse effectsLuethi D, Liechti ME · Archives of Toxicologydoi:10.1007/s00204-020-02693-7strongconsumed1 section
2020Synthetic psychoactive cathinones: hypothermia and reduced lethality compared to methamphetamine and MDMAMuskiewicz DE, Resendiz-Gutierrez F, Issa O, Hall FS · Pharmacology, Biochemistry and Behaviordoi:10.1016/j.pbb.2020.172871moderateconsumed1 section
2019Dose-Response Pharmacological Study of Mephedrone and Its Metabolites: Pharmacokinetics, Serotoninergic Effects, and Impact of CYP2D6 Genetic VariationOlesti E, Farre M, Carbo ML, et al. · Clinical Pharmacology and Therapeuticsdoi:10.1002/cpt.1417strongconsumed4 sections
2019Mephedrone and Alcohol Interactions in HumansPapaseit E, Perez-Mana C, de Sousa Fernandes Perna EB, et al. · Frontiers in Pharmacologydoi:10.3389/fphar.2019.01588strongconsumed4 sections
2019Polytox synthetic cathinone abuse: role for organic cation transporter 3Mayer FP, Schmid D, Holy M, Daws LC, Sitte HH · Neurochemistry Internationaldoi:10.1016/j.neuint.2018.09.008moderateconsumed4 sections
2018Neuropharmacology of Synthetic CathinonesBaumann MH, Walters HM, Niello M, Sitte HH · Handbook of Experimental Pharmacologydoi:10.1007/164_2018_178moderateconsumed2 sections
2017GC-MS Quantification Method for Mephedrone in Plasma and Urine: Application to Human PharmacokineticsOlesti E, Pujadas M, Papaseit E, et al. · Journal of Analytical Toxicologydoi:10.1093/jat/bkw120moderateconsumed2 sections
2017Neurotoxicology of Synthetic Cathinone AnalogsAngoa-Perez M, Anneken JH, Kuhn DM · Current Topics in Behavioral Neurosciencesdoi:10.1007/7854_2016_21moderateconsumed1 section
2017Pharmacokinetics of Mephedrone and Its Metabolites in Human by LC-MS/MSOlesti E, Farre M, Papaseit E, et al. · The AAPS Journaldoi:10.1208/s12248-017-0132-2moderateconsumed1 section
2017Stereoselective Differences between the Reinforcing and Motivational Effects of Cathinone-Derived 4-Methylmethcathinone (Mephedrone) in Self-Administering RatsPhilogene-Khalid HL, Simmons SJ, Nayak S, et al. · ACS Chemical Neurosciencedoi:10.1021/acschemneuro.7b00212moderateconsumed3 sections
2016Human Pharmacology of Mephedrone in Comparison with MDMAPapaseit E, Pérez-Mañá C, Mateus JA, et al. · Neuropsychopharmacologydoi:10.1038/npp.2016.75strongconsumed5 sections
2015Mephedrone related fatalities: a reviewBusardo FP, Kyriakou C, Napoletano S, Marinelli E, Zaami S · European Review for Medical and Pharmacological Sciencespmid:26502870moderateconsumed1 section
2015Self-reported prevalence of dependence of MDMA compared to cocaine, mephedrone and ketamine among a sample of recreational poly-drug usersUosukainen H, Tacke U, Winstock AR · International Journal on Drug Policydoi:10.1016/j.drugpo.2014.07.004moderateconsumed1 section
2014A 3-year review of new psychoactive substances in caseworkElliott S, Evans J · Forensic Science Internationaldoi:10.1016/j.forsciint.2014.04.017moderateconsumed2 sections
2014Abuse-related and abuse-limiting effects of methcathinone and the synthetic bath salts cathinone analogs MDPV, methylone and mephedrone on intracranial self-stimulation in ratsBonano JS, Glennon RA, De Felice LJ, Banks ML, Negus SS · Psychopharmacologydoi:10.1007/s00213-013-3223-5moderateconsumed2 sections
2014Manganese-enhanced magnetic resonance imaging reveals differential long-term neuroadaptation after methamphetamine and mephedroneden Hollander B, Dudek M, Ojanpera I, et al. · International Journal of Neuropsychopharmacologydoi:10.1093/ijnp/pyu106moderateconsumed1 section
2013Bath salts intoxication: a case seriesImam SF, Patel H, Mahmoud M, et al. · Journal of Emergency Medicinedoi:10.1016/j.jemermed.2013.04.017weakconsumed1 section
2013Changes in ambient temperature differentially alter the thermoregulatory, cardiac and locomotor stimulant effects of 4-methylmethcathinone (mephedrone)Miller ML, Creehan KM, Angrish D, et al. · Drug and Alcohol Dependencedoi:10.1016/j.drugalcdep.2012.07.003moderateconsumed2 sections
2013Differential effects of cathinone compounds and MDMA on body temperature in the rat, and pharmacological characterization of mephedrone-induced hypothermiaShortall SE, Green AR, Swift KM, Fone KC, King MV · British Journal of Pharmacologydoi:10.1111/j.1476-5381.2012.02236.xmoderateconsumed2 sections
2013In vitro metabolism studies on mephedrone and analysis of forensic casesPedersen AJ, Reitzel LA, Johansen SS, Linnet K · Drug Testing and Analysisdoi:10.1002/dta.1369moderateconsumed3 sections
2013Long-term cognitive and neurochemical effects of bath salt designer drugs methylone and mephedroneden Hollander B, Rozov S, Linden AM, et al. · Pharmacology, Biochemistry and Behaviordoi:10.1016/j.pbb.2012.10.006moderateconsumed2 sections
2013Mephedrone (4-methylmethcathinone) supports intravenous self-administration in Sprague-Dawley and Wistar ratsAarde SM, Angrish D, Barlow DJ, et al. · Addiction Biologydoi:10.1111/adb.12038moderateconsumed2 sections
2012Comparative neuropharmacology of three psychostimulant cathinone derivatives: butylone, mephedrone and methyloneLopez-Arnau R, Martinez-Clemente J, Pubill D, Escubedo E, Camarasa J · British Journal of Pharmacologydoi:10.1111/j.1476-5381.2012.01998.xmoderateconsumed2 sections
2012Effect of ambient temperature on the thermoregulatory and locomotor stimulant effects of 4-methylmethcathinone in Wistar and Sprague-Dawley ratsWright MJ, Angrish D, Aarde SM, et al. · PLoS ONEdoi:10.1371/journal.pone.0044652moderateconsumed2 sections
Show all 41 sources — 11 more
Sources 31 to 41
yearsourcetierstatusfeeds
2012Mephedrone, a new designer drug of abuse, produces acute hemodynamic effects in the ratMeng H, Cao J, Kang J, et al. · Toxicology Lettersdoi:10.1016/j.toxlet.2011.10.010moderateconsumed3 sections
2012Pharmacological characterization of designer cathinones in vitroSimmler LD, Buser TA, Donzelli M, et al. · British Journal of Pharmacologydoi:10.1111/j.1476-5381.2012.02145.xmoderateconsumed3 sections
2012The designer methcathinone analogs, mephedrone and methylone, are substrates for monoamine transporters in brain tissueBaumann MH, Ayestas MA, Partilla JS, et al. · Neuropsychopharmacologydoi:10.1038/npp.2011.304moderateconsumed7 sections
20114-Methylmethcathinone (mephedrone): neuropharmacological effects of a designer stimulant of abuseHadlock GC, Webb KM, McFadden LM, et al. · Journal of Pharmacology and Experimental Therapeuticsdoi:10.1124/jpet.111.184119moderateconsumed3 sections
2011Mephedrone (4-methylmethcathinone; 'meow meow'): chemical, pharmacological and clinical issuesSchifano F, Albanese A, Fergus S, et al. · Psychopharmacologydoi:10.1007/s00213-010-2070-xmoderateconsumed2 sections
2011Mephedrone Legal Status by Jurisdiction (Erowid)Erowidurl:ef3c1c9e5932c845weakconsumedcited only
2011Mephedrone, compared with MDMA (ecstasy) and amphetamine, rapidly increases both dopamine and 5-HT levels in nucleus accumbens of awake ratsKehr J, Ichinose F, Yoshitake S, et al. · British Journal of Pharmacologydoi:10.1111/j.1476-5381.2011.01499.xmoderateconsumed3 sections
2011Mephedrone: use, subjective effects and health risksWinstock A, Mitcheson L, Ramsey J, et al. · Addictiondoi:10.1111/j.1360-0443.2011.03502.xmoderateconsumed2 sections
2010Multiple-drug toxicity caused by the coadministration of 4-methylmethcathinone (mephedrone) and heroinDickson AJ, Vorce SP, Levine B, Past MR · Journal of Analytical Toxicologypmid:20406541weakconsumed1 section
2010Recreational use of mephedrone (4-methylmethcathinone, 4-MMC) with associated sympathomimetic toxicityWood DM, Davies S, Puchnarewicz M, et al. · Journal of Medical Toxicologydoi:10.1007/s13181-010-0018-5weakconsumed1 section
2010The serotonin syndrome as a result of mephedrone toxicityGarrett G, Sweeney M · BMJ Case Reportsdoi:10.1136/bcr.04.2010.2925weakconsumed1 section

4Docket

one filing per activity — decisions, correspondence, reports

  1. 0012026-04-20revisionRevision 1

    Initial LLM generation (v5 pipeline, wiki)

    psx:substance/mephedrone/version/1
  2. 0022026-04-21proposaldose_tier · threshold
  3. 0032026-04-21proposaldose_tier · light
  4. 0042026-04-21proposaldose_tier · common
  5. 0052026-04-21proposaldose_tier · strong
  6. 0062026-04-21proposaldose_tier · heavy
  7. 0072026-04-21proposaltimeline · oral · onset
  8. 0082026-04-21proposaltimeline · oral · come_up
  9. 0092026-04-21proposaltimeline · oral · peak
  10. 0102026-04-21proposaltimeline · oral · plateau
  11. 0112026-04-21proposaltimeline · oral · resolution
  12. 0122026-04-21proposaltimeline · oral · afterglow
  13. 0132026-04-21proposaltimeline · insufflated · onset
  14. 0142026-04-21proposaltimeline · insufflated · come_up
  15. 0152026-04-21proposaltimeline · insufflated · peak
  16. 0162026-04-21proposaltimeline · insufflated · resolution
  17. 0172026-04-21proposaltimeline · insufflated · afterglow
  18. 0182026-04-21proposaltoxicity
  19. 0192026-04-21proposaldependence · full
  20. 0202026-04-21proposalwithdrawal
  21. 0212026-04-21proposaltolerance
  22. 0222026-04-21proposaldosage · oral
  23. 0232026-04-21proposaldosage · insufflated
  24. 0242026-04-21proposalduration · oral · onset
  25. 0252026-04-21proposalduration · oral · come_up
  26. 0262026-04-21proposalduration · oral · peak
  27. 0272026-04-21proposalduration · oral · offset
  28. 0282026-04-21proposalduration · oral · total
  29. 0292026-04-21proposalduration · oral · aftereffects
  30. 0302026-04-21proposalduration · insufflated · onset
  31. 0312026-04-21proposalduration · insufflated · come_up
  32. 0322026-04-21proposalduration · insufflated · peak
  33. 0332026-04-21proposalduration · insufflated · offset
  34. 0342026-04-21proposalduration · insufflated · total
  35. 0352026-04-21proposalduration · insufflated · aftereffects
  36. 0362026-06-04proposal42 value proposals approved together

    one review action inferred from a shared reviewer and instant — the graph records one activity per proposal

    42 items in this filing

    • dose_tier · light
    • dose_tier · common
    • dose_tier · strong
    • dose_tier · heavy
    • timeline · oral · onset
    • timeline · oral · come_up
    • timeline · oral · peak
    • timeline · oral · plateau
    • timeline · oral · resolution
    • timeline · oral · afterglow
    • timeline · insufflated · onset
    • timeline · insufflated · come_up
    • timeline · insufflated · peak
    • timeline · insufflated · plateau
    • timeline · insufflated · resolution
    • timeline · insufflated · afterglow
    • toxicity
    • dependence · full
    • withdrawal
    • tolerance
    • dosage · oral
    • dosage · insufflated
    • duration · oral · onset
    • duration · oral · come_up
    • duration · oral · peak
    • duration · oral · offset
    • duration · oral · total
    • duration · oral · aftereffects
    • duration · insufflated · onset
    • duration · insufflated · come_up
    • duration · insufflated · peak
    • duration · insufflated · offset
    • duration · insufflated · total
    • duration · insufflated · aftereffects
    • contraindication · metabolic
    • contraindication · cardiovascular
    • contraindication · psychiatric
    • contraindication · other
    • contraindication · other
    • contraindication · pregnancy_breastfeeding
    • contraindication · psychiatric
    psx:substance/mephedrone/proposal/dose_tier/46f76ec0-8d04-4a2c-86cf-ff1de127f070
  37. 0372026-06-04publicationPublication — backfill

5Issued documents

what the notice, info card and emergency page said, by hash

Issued documents
documentcontent hashissuedfrom versionsuperseded
info_card1e3038aebd826927a596964c…2026-10-19 20:32Revision 1current
emergency47cf1475db8db7f236c6a01a…2026-09-04 04:30Revision 1current
info_card29319cdac70f1bced1950cf2…2026-09-04 04:30Revision 1superseded2026-10-19
notice6092867e67a34b1ffc5c2d45…2026-09-04 04:30Revision 1current