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Psychedex

1Provenance card

the boundary, as counts

Sources

4137 with DOI

4 strong · 31 moderate · 6 weak

Compilations

12026-04-20T23:32:24.316Z

pipeline-v5 · prompt hash not recorded — run predates 2026-09

Decisions

78last ruled 2026-06-04

0 awaiting a ruling

Issued documents

42026-10-19T20:32:45.725Z

notice · info card · emergency

Searches

210 with no results

queries and counts on the build

Claims checked

1234 supported

4 supported · 119 not

Correspondence

0received

consent field ships in Phase 4

Edges

365

derivations recorded for this entity

Complete over 41 sources, 1 compilation, and 78 decisions.Not here: the private journal (never).Working material — drafts, discards, unsupported claims — is listed below and readable on the working page.Cite: psychedex.org/substances/mephedrone/archive

Timeline

what happened, newest first — claims, searches and artifacts stay inside Build

  1. 2026-10-19issueIssued info_card
  2. 2026-09-24srcDose-Response Pharmacological Study of Mephedrone and Its Metabolites: Pharmacokinetics, Serotoninergic Effects, and Impact of CYP2D6 Genetic Variation
  3. 2026-09-24srcIn vitro metabolism studies on mephedrone and analysis of forensic cases
  4. 2026-09-24srcNeuropharmacology of Synthetic Cathinones
  5. 2026-09-24srcNeurotoxicology of Synthetic Cathinone Analogs
  6. 2026-09-24srcDesigner drugs: mechanism of action and adverse effects
  7. 2026-09-24srcMephedrone (4-methylmethcathinone; 'meow meow'): chemical, pharmacological and clinical issues
  8. 2026-09-24srcAbuse-related and abuse-limiting effects of methcathinone and the synthetic bath salts cathinone analogs MDPV, methylone and mephedrone on intracranial self-stimulation in rats
  9. 2026-09-24srcRecreational use of mephedrone (4-methylmethcathinone, 4-MMC) with associated sympathomimetic toxicity
  10. 2026-09-24srcChanges in ambient temperature differentially alter the thermoregulatory, cardiac and locomotor stimulant effects of 4-methylmethcathinone (mephedrone)
  11. 2026-09-24srcSelf-reported prevalence of dependence of MDMA compared to cocaine, mephedrone and ketamine among a sample of recreational poly-drug users
  12. 2026-09-24srcA 3-year review of new psychoactive substances in casework
  13. 2026-09-24srcChemsex-related deaths in the United Kingdom (2017-2022): A review of the Forensic Toxicology data
  14. 2026-09-24srcBath salts intoxication: a case series
  15. 2026-09-24srcPolytox synthetic cathinone abuse: role for organic cation transporter 3
  16. 2026-09-24srcMephedrone induces partial release at human dopamine transporters but full release at human serotonin transporters
  17. 2026-09-24srcLong-term cognitive and neurochemical effects of bath salt designer drugs methylone and mephedrone
  18. 2026-09-24srcSynthetic psychoactive cathinones: hypothermia and reduced lethality compared to methamphetamine and MDMA
  19. 2026-09-24srcMephedrone, a new designer drug of abuse, produces acute hemodynamic effects in the rat
  20. 2026-09-24srcStereoselective Differences between the Reinforcing and Motivational Effects of Cathinone-Derived 4-Methylmethcathinone (Mephedrone) in Self-Administering Rats
  21. 2026-09-24srcThe designer methcathinone analogs, mephedrone and methylone, are substrates for monoamine transporters in brain tissue
  22. 2026-09-24srcHuman Pharmacology of Mephedrone in Comparison with MDMA
  23. 2026-09-24srcManganese-enhanced magnetic resonance imaging reveals differential long-term neuroadaptation after methamphetamine and mephedrone
  24. 2026-09-24srcPharmacokinetics of Mephedrone and Its Metabolites in Whole Blood and Plasma after Controlled Intranasal Administration to Healthy Human Volunteers
  25. 2026-09-24srcGC-MS Quantification Method for Mephedrone in Plasma and Urine: Application to Human Pharmacokinetics
  26. 2026-09-24srcMephedrone (4-methylmethcathinone) supports intravenous self-administration in Sprague-Dawley and Wistar rats
  27. 2026-09-24srcMephedrone: use, subjective effects and health risks
  28. 2026-09-24srcMephedrone, compared with MDMA (ecstasy) and amphetamine, rapidly increases both dopamine and 5-HT levels in nucleus accumbens of awake rats
  29. 2026-09-24srcComparative neuropharmacology of three psychostimulant cathinone derivatives: butylone, mephedrone and methylone
  30. 2026-09-24srcPharmacological characterization of designer cathinones in vitro
  31. 2026-09-24srcDifferential effects of cathinone compounds and MDMA on body temperature in the rat, and pharmacological characterization of mephedrone-induced hypothermia
  32. 2026-09-24src4-Methylmethcathinone (mephedrone): neuropharmacological effects of a designer stimulant of abuse
  33. 2026-09-24srcNeurochemical and Cardiovascular Effects of 4-Chloro Ring-Substituted Synthetic Cathinones in Rats
  34. 2026-09-24srcThe serotonin syndrome as a result of mephedrone toxicity
  35. 2026-09-24srcPharmacokinetics of Mephedrone and Its Metabolites in Human by LC-MS/MS
  36. 2026-09-24srcEffect of ambient temperature on the thermoregulatory and locomotor stimulant effects of 4-methylmethcathinone in Wistar and Sprague-Dawley rats
  37. 2026-09-24srcMephedrone and Alcohol Interactions in Humans
  38. 2026-09-24srcAcute Pharmacological Effects of Oral and Intranasal Mephedrone: An Observational Study in Humans
  39. 2026-09-24srcMultiple-drug toxicity caused by the coadministration of 4-methylmethcathinone (mephedrone) and heroin
  40. 2026-09-24srcMephedrone related fatalities: a review
  41. 2026-09-24srcMephedrone Legal Status by Jurisdiction (Erowid)
  42. 2026-09-24srcSMILES and physical properties of mephedrone (CID 45266826)
  43. 2026-09-04issueIssued emergency
  44. 2026-09-04issueIssued info_card
  45. 2026-09-04issueIssued notice
  46. 2026-06-04proposal42 value proposals approved togetherone review action inferred from a shared reviewer and instant — the graph records one activity per proposal
  47. 2026-06-04publicationPublication — backfill
  48. 2026-04-21proposalduration · insufflated · aftereffects
  49. 2026-04-21proposalduration · insufflated · total
  50. 2026-04-21proposalduration · insufflated · offset
  51. 2026-04-21proposalduration · insufflated · peak
  52. 2026-04-21proposalduration · insufflated · come_up
  53. 2026-04-21proposalduration · insufflated · onset
  54. 2026-04-21proposalduration · oral · aftereffects
  55. 2026-04-21proposalduration · oral · total
  56. 2026-04-21proposalduration · oral · offset
  57. 2026-04-21proposalduration · oral · peak
  58. 2026-04-21proposalduration · oral · come_up
  59. 2026-04-21proposalduration · oral · onset
  60. 2026-04-21proposaldosage · insufflated
  61. 2026-04-21proposaldosage · oral
  62. 2026-04-21proposaltolerance
  63. 2026-04-21proposalwithdrawal
  64. 2026-04-21proposaldependence · full
  65. 2026-04-21proposaltoxicity
  66. 2026-04-21proposaltimeline · insufflated · afterglow
  67. 2026-04-21proposaltimeline · insufflated · resolution
  68. 2026-04-21proposaltimeline · insufflated · peak
  69. 2026-04-21proposaltimeline · insufflated · come_up
  70. 2026-04-21proposaltimeline · insufflated · onset
  71. 2026-04-21proposaltimeline · oral · afterglow
  72. 2026-04-21proposaltimeline · oral · resolution
  73. 2026-04-21proposaltimeline · oral · plateau
  74. 2026-04-21proposaltimeline · oral · peak
  75. 2026-04-21proposaltimeline · oral · come_up
  76. 2026-04-21proposaltimeline · oral · onset
  77. 2026-04-21proposaldose_tier · heavy
  78. 2026-04-21proposaldose_tier · strong
  79. 2026-04-21proposaldose_tier · common
  80. 2026-04-21proposaldose_tier · light
  81. 2026-04-21proposaldose_tier · threshold
  82. 2026-04-20revisionRevision 1
  83. 2026-04-20genGeneration — pipeline-v5pipeline-v5
  84. 2026-04-20rungeneration run

The same entries, as forms: six forms.