Mephedrone

Closure of psx:substance/mephedrone/section/history.full@1: 48 upstream, 22 downstream.

psx:substance/mephedrone/section/history.full@1
├─ informed_by  claim/a0769adf-05c1-4ac6-b0fc-8d3fbd4e1dba  Claim in history — inconclusive  working
├─ informed_by  claim/bfd4b768-d351-4578-93e4-db36fc8cb067  Claim in history — inconclusive  working
├─ informed_by  claim/b1092639-5a69-4963-b4b4-059a08f31d73  Claim in history — inconclusive  working
├─ informed_by  claim/4c160491-5c40-450a-babe-a5a80c9fb2fe  Claim in history — inconclusive  working
├─ informed_by  claim/aab00a7f-fc07-42cc-ba0e-737622e781b6  Claim in history — inconclusive  working
  ├─ used  src/doi:10.1016/j.forsciint.2014.04.017  A 3-year review of new psychoactive substances in casework
  ├─ used  src/doi:10.1016/j.forsciint.2025.112553  Chemsex-related deaths in the United Kingdom (2017-2022): A review of the Forensic Toxicology data
  ├─ used  src/doi:10.1007/s00213-010-2070-x  Mephedrone (4-methylmethcathinone; 'meow meow'): chemical, pharmacological and clinical issues
  ├─ used  src/doi:10.1038/npp.2016.75  Human Pharmacology of Mephedrone in Comparison with MDMA
  ├─ used  src/doi:10.3389/fphar.2019.01588  Mephedrone and Alcohol Interactions in Humans
      ├─ used  src/doi:10.1038/npp.2011.304  The designer methcathinone analogs, mephedrone and methylone, are substrates for monoamine transporters in brain tissue
      ├─ used  src/doi:10.1111/j.1476-5381.2012.02145.x  Pharmacological characterization of designer cathinones in vitro
      ├─ used  src/doi:10.1093/jat/bkw120  GC-MS Quantification Method for Mephedrone in Plasma and Urine: Application to Human Pharmacokinetics
      ├─ used  src/url:ef3c1c9e5932c845  Mephedrone Legal Status by Jurisdiction (Erowid)
      ├─ used  src/doi:10.1016/j.neuropharm.2023.109704  Mephedrone induces partial release at human dopamine transporters but full release at human serotonin transporters
      ├─ used  src/doi:10.1002/cpt.1417  Dose-Response Pharmacological Study of Mephedrone and Its Metabolites: Pharmacokinetics, Serotoninergic Effects, and Impact of CYP2D6 Genetic Variation
      ├─ used  src/doi:10.1111/j.1476-5381.2011.01499.x  Mephedrone, compared with MDMA (ecstasy) and amphetamine, rapidly increases both dopamine and 5-HT levels in nucleus accumbens of awake rats
      ├─ used  src/doi:10.1016/j.toxlet.2011.10.010  Mephedrone, a new designer drug of abuse, produces acute hemodynamic effects in the rat
      ├─ used  src/doi:10.1136/bcr.04.2010.2925  The serotonin syndrome as a result of mephedrone toxicity
      ├─ used  src/doi:10.1111/j.1360-0443.2011.03502.x  Mephedrone: use, subjective effects and health risks
      ├─ used  src/doi:10.1124/jpet.111.184119  4-Methylmethcathinone (mephedrone): neuropharmacological effects of a designer stimulant of abuse
      ├─ used  src/url:f0071bcdab06c69f  SMILES and physical properties of mephedrone (CID 45266826)
      ├─ used  src/doi:10.1021/acschemneuro.7b00212  Stereoselective Differences between the Reinforcing and Motivational Effects of Cathinone-Derived 4-Methylmethcathinone (Mephedrone) in Self-Administering Rats
      ├─ used  src/doi:10.1007/164_2018_178  Neuropharmacology of Synthetic Cathinones
      ├─ used  src/doi:10.1016/j.neuint.2018.09.008  Polytox synthetic cathinone abuse: role for organic cation transporter 3
      ├─ used  src/doi:10.1093/jat/bkaa134  Pharmacokinetics of Mephedrone and Its Metabolites in Whole Blood and Plasma after Controlled Intranasal Administration to Healthy Human Volunteers
      ├─ used  src/doi:10.3390/ph14020100  Acute Pharmacological Effects of Oral and Intranasal Mephedrone: An Observational Study in Humans
      ├─ used  src/doi:10.1002/dta.1369  In vitro metabolism studies on mephedrone and analysis of forensic cases
      ├─ used  src/doi:10.1208/s12248-017-0132-2  Pharmacokinetics of Mephedrone and Its Metabolites in Human by LC-MS/MS
      ├─ used  src/doi:10.1111/j.1476-5381.2012.01998.x  Comparative neuropharmacology of three psychostimulant cathinone derivatives: butylone, mephedrone and methylone
      ├─ used  src/doi:10.1111/adb.12038  Mephedrone (4-methylmethcathinone) supports intravenous self-administration in Sprague-Dawley and Wistar rats
      ├─ used  src/doi:10.1007/s00213-013-3223-5  Abuse-related and abuse-limiting effects of methcathinone and the synthetic bath salts cathinone analogs MDPV, methylone and mephedrone on intracranial self-stimulation in rats
      ├─ used  src/doi:10.1016/j.pbb.2012.10.006  Long-term cognitive and neurochemical effects of bath salt designer drugs methylone and mephedrone
      ├─ used  src/doi:10.1093/ijnp/pyu106  Manganese-enhanced magnetic resonance imaging reveals differential long-term neuroadaptation after methamphetamine and mephedrone
      ├─ used  src/doi:10.1007/7854_2016_21  Neurotoxicology of Synthetic Cathinone Analogs
      ├─ used  src/doi:10.1111/j.1476-5381.2012.02236.x  Differential effects of cathinone compounds and MDMA on body temperature in the rat, and pharmacological characterization of mephedrone-induced hypothermia
      ├─ used  src/doi:10.1371/journal.pone.0044652  Effect of ambient temperature on the thermoregulatory and locomotor stimulant effects of 4-methylmethcathinone in Wistar and Sprague-Dawley rats
      ├─ used  src/doi:10.1016/j.drugalcdep.2012.07.003  Changes in ambient temperature differentially alter the thermoregulatory, cardiac and locomotor stimulant effects of 4-methylmethcathinone (mephedrone)
      ├─ used  src/doi:10.1007/s13181-010-0018-5  Recreational use of mephedrone (4-methylmethcathinone, 4-MMC) with associated sympathomimetic toxicity
      ├─ used  src/doi:10.1016/j.jemermed.2013.04.017  Bath salts intoxication: a case series
      ├─ used  src/doi:10.1124/jpet.122.001478  Neurochemical and Cardiovascular Effects of 4-Chloro Ring-Substituted Synthetic Cathinones in Rats
      ├─ used  src/doi:10.1016/j.pbb.2020.172871  Synthetic psychoactive cathinones: hypothermia and reduced lethality compared to methamphetamine and MDMA
      ├─ used  src/pmid:20406541  Multiple-drug toxicity caused by the coadministration of 4-methylmethcathinone (mephedrone) and heroin
      ├─ used  src/pmid:26502870  Mephedrone related fatalities: a review
      ├─ used  src/doi:10.1007/s00204-020-02693-7  Designer drugs: mechanism of action and adverse effects
      ├─ used  src/doi:10.1016/j.drugpo.2014.07.004  Self-reported prevalence of dependence of MDMA compared to cocaine, mephedrone and ketamine among a sample of recreational poly-drug users
      ├─ derived_from  gen/25618495-032d-4439-b758-e10a0e03004e  Generation — pipeline-v5
      └─ generated_by  pub/e4b45656-8984-4967-a869-d24533e60737  Publication — backfill
    ├─ used  version/1  Revision 1
    ├─ used  claim/fd48a95c-5b1b-48a0-8015-ff019f0f969e  Claim in safety — inconclusive  working
    ├─ used  claim/d2a6691f-6278-4516-9cd1-63097bf1e4f6  Claim in safety — inconclusive  working
    ├─ used  claim/2cea9b00-ef3e-475d-937f-ec53e8748b31  Claim in summary — inconclusive  working
    ├─ used  claim/9be32abc-37eb-4312-99c1-59b1f56c0967  Claim in summary — inconclusive  working
    ├─ used  claim/911b350b-753f-4e58-a38e-28f0031994b4  Claim in summary — inconclusive  working
    ├─ used  claim/38f5048a-0a87-4a18-9426-2f444c4110f7  Claim in pharmacology — inconclusive  working
    ├─ used  claim/4682bce6-6de8-4c92-b494-a90752cc373c  Claim in clinical-evidence — inconclusive  working
    ├─ used  claim/cdbdade7-f53b-4396-9725-6dab396d8733  Claim in effects-overview — inconclusive  working
    ├─ used  claim/7c72d615-44cb-4185-82d9-d6cbe98871a9  Claim in summary — inconclusive  working
    ├─ used  claim/c7c665b3-3a99-46fa-9a93-6f23dbd73ca3  Claim in clinical-evidence — inconclusive  working
    ├─ used  claim/52ffe836-aa37-4968-97c2-eaa520ede2dc  Claim in safety — inconclusive  working
    ├─ used  claim/4e83f5eb-4e7f-498b-8cbb-bf86785d223b  Claim in safety — inconclusive  working
      ├─ derived_from  issue/notice@6092867e67a3  Issued notice
      ├─ derived_from  issue/info_card@29319cdac70f  Issued info_card
      ├─ derived_from  issue/emergency@47cf1475db8d  Issued emergency
      ├─ derived_from  issue/info_card@1e3038aebd82  Issued info_card
      ├─ informed_by  section/safety.full@1
      ├─ informed_by  section/summary.full@1
      ├─ informed_by  section/pharmacology.full@1
      ├─ informed_by  section/clinical-evidence.full@1
      └─ informed_by  section/effects-overview.full@1
… closure truncated at 200 nodes

indented by distance from this node, not by parentage