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Psychedex

Standing risks

  • Compulsive use risk, monitor frequencyconfidence medium
    Compulsive redosing
    high
    Dose escalation
    moderate
    View in article

Lethal interactions

Specific substances

  • Tramadollethal

Dangerous interactions

29 dangerous interactions recorded for this substance.

See the full interactions table

Contraindications

Cardiovascular

  • hypertensionabsolute

    Uncontrolled or poorly controlled hypertension is an absolute contraindication.

  • coronary artery diseaseabsolute

    Coronary artery disease is an absolute contraindication due to risk of acute myocardial ischemia.

  • cardiac arrhythmiasabsolute

    Pre-existing arrhythmias are an absolute contraindication.

Neurological

  • epilepsyabsolute

    Seizure disorders are an absolute contraindication.

Psychiatric

  • psychotic disordersrelative

    History of psychotic disorders is a relative contraindication.

  • bipolar disorderrelative

    Bipolar disorder is a relative contraindication due to risk of precipitating mania.

Hepatic

  • hepatic impairmentrelative

    Hepatic impairment is a relative contraindication given pentedrone's class-leading in vitro hepatotoxicity.

Pregnancy & Breastfeeding

  • pregnancy and breastfeedingabsolute

    Pregnancy and breastfeeding are absolute contraindications.

Other

  • MAOI useabsolute

    Concurrent or recent MAOI use (within 14 days) is an absolute contraindication.

If this is going wrong

Emergency — Pentedrone Crisis resources Emergency card

Reducing or stopping

Withdrawal timelines Tolerance recovery