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1Provenance card

the boundary, as counts

Sources

3631 with DOI

14 strong · 11 moderate · 11 weak

Compilations

12026-04-25T22:30:57.616Z

pipeline-v5 · prompt hash not recorded — run predates 2026-09

Decisions

44last ruled 2026-06-04

0 awaiting a ruling

Issued documents

42026-10-19T20:32:41.516Z

notice · info card · emergency

Searches

252 with no results

queries and counts on the build

Claims checked

136106 supported

106 supported · 30 not

Correspondence

0received

consent field ships in Phase 4

Edges

390

derivations recorded for this entity

Complete over 36 sources, 1 compilation, and 44 decisions.Not here: the private journal (never).Working material — drafts, discards, unsupported claims — is listed below and readable on the working page.Cite: psychedex.org/substances/mdpv/archive

Timeline

what happened, newest first — claims, searches and artifacts stay inside Build

  1. 2026-10-19issueIssued info_card
  2. 2026-09-24srcStudies on the metabolism of the alpha-pyrrolidinophenone designer drug methylenedioxy-pyrovalerone (MDPV) in rat and human urine and human liver microsomes using GC-MS and LC-high-resolution MS and its detectability in urine by GC-MS
  3. 2026-09-24srcNeuropharmacology of 3,4-Methylenedioxypyrovalerone (MDPV), Its Metabolites, and Related Analogs
  4. 2026-09-24srcAbuse-related and abuse-limiting effects of methcathinone and the synthetic bath salts cathinone analogs MDPV, methylone and mephedrone on intracranial self-stimulation in rats
  5. 2026-09-24srcBinge-like acquisition of 3,4-methylenedioxypyrovalerone (MDPV) self-administration and wheel activity in rats
  6. 2026-09-24srcBehavioral economic analysis of the reinforcing effects of 'bath salts' mixtures: studies with MDPV, methylone, and caffeine in male Sprague-Dawley rats
  7. 2026-09-24srcEffects of MDPV on dopamine transporter regulation in male rats. Comparison with cocaine
  8. 2026-09-24srcIn vitro Phase I and Phase II metabolism of alpha-pyrrolidinovalerophenone (alpha-PVP), methylenedioxypyrovalerone (MDPV) and methedrone by human liver microsomes and human liver cytosol
  9. 2026-09-24srcA case of fatal idiosyncratic reaction to the designer drug 3,4-methylenedioxypyrovalerone (MDPV) and review of the literature
  10. 2026-09-24srcDeath following recreational use of designer drug 'bath salts' containing 3,4-Methylenedioxypyrovalerone (MDPV)
  11. 2026-09-24src'Bath salts' and 'plant food' products: the experience of one regional US poison center
  12. 2026-09-24srcPsychoactive 'bath salts' intoxication with methylenedioxypyrovalerone
  13. 2026-09-24srcHyperthermia and multiorgan failure after abuse of 'bath salts' containing 3,4-methylenedioxypyrovalerone
  14. 2026-09-24srcSubstituted methcathinones differ in transporter and receptor interactions
  15. 2026-09-24srcFunctional connectivity, behavioral and dopaminergic alterations 24 hours following acute exposure to synthetic bath salt drug methylenedioxypyrovalerone
  16. 2026-09-24srcNon-conserved residues dictate dopamine transporter selectivity for the potent synthetic cathinone and psychostimulant MDPV
  17. 2026-09-24src3,4-methylenedioxypyrovalerone (MDPV): chemistry, pharmacology and toxicology of a new designer drug of abuse marketed online
  18. 2026-09-24srcPowerful cocaine-like actions of 3,4-methylenedioxypyrovalerone (MDPV), a principal constituent of psychoactive 'bath salts' products
  19. 2026-09-24srcLocomotor Stimulant and Rewarding Effects of Inhaling Methamphetamine, MDPV, and Mephedrone via Electronic Cigarette-Type Technology
  20. 2026-09-24srcPolydrug fatal intoxication involving MDPHP: Detection and in silico investigation of multiple 3,4-methylenedioxy-derived designer drugs and their metabolites
  21. 2026-09-24srcPostmortem tissue distribution of MDPV following lethal intoxication by 'bath salts'
  22. 2026-09-24srcElectroconvulsive therapy improves persistent psychosis after repeated use of methylenedioxypyrovalerone ('bath salts')
  23. 2026-09-24srcDeaths involving methylenedioxypyrovalerone (MDPV) in Upper East Tennessee
  24. 2026-09-24srcLinear pharmacokinetics of 3,4-methylenedioxypyrovalerone (MDPV) and its metabolites in the rat: relationship to pharmacodynamic effects
  25. 2026-09-24srcCardiovascular and locomotor effects of binary mixtures of common 'bath salts' constituents: Studies with methylone, methylenedioxypyrovalerone and caffeine in rats
  26. 2026-09-24srcPotent rewarding and reinforcing effects of the synthetic cathinone 3,4-methylenedioxypyrovalerone (MDPV)
  27. 2026-09-24srcPharmacological characterization of designer cathinones in vitro
  28. 2026-09-24srcEmerging drugs of abuse: current perspectives on substituted cathinones
  29. 2026-09-24srcClinical experience with and analytical confirmation of 'bath salts' and 'legal highs' (synthetic cathinones) in the United States
  30. 2026-09-24srcSynthetic Cathinone and Cannabinoid Designer Drugs Pose a Major Risk for Public Health
  31. 2026-09-24srcBehavioural, Pharmacokinetic, Metabolic, and Hyperthermic Profile of 3,4-Methylenedioxypyrovalerone (MDPV) in the Wistar Rat
  32. 2026-09-24srcIntegrated Assessment of the Cardiotoxic and Neurobehavioral Effects of 3,4-Methylenedioxypyrovalerone (MDPV) in Zebrafish Embryos
  33. 2026-09-24srcEmergency department visits after use of a drug sold as 'bath salts'--Michigan, November 13, 2010-March 31, 2011
  34. 2026-09-24srcSympathomimetic syndrome, choreoathetosis, and acute kidney injury following 'bath salts' injection
  35. 2026-09-24srcThe Psychotic Couple--Sharing Drugs or Delusions?
  36. 2026-09-24srcMDPV legal status and scheduling history
  37. 2026-09-24srcEMCDDA-Europol Joint Report on MDPV (3,4-methylenedioxypyrovalerone)
  38. 2026-09-04issueIssued emergency
  39. 2026-09-04issueIssued info_card
  40. 2026-09-04issueIssued notice
  41. 2026-06-04proposal42 value proposals approved togetherone review action inferred from a shared reviewer and instant — the graph records one activity per proposal
  42. 2026-06-04publicationPublication — backfill
  43. 2026-04-25revisionRevision 1
  44. 2026-04-25absenceSearched ClinicalTrials.gov for "MDPV methylenedioxypyrovalerone" — no results
  45. 2026-04-25absenceSearched PubMed for "MDPV cathinone tramadol serotonin toxicity death interaction" — no results
  46. 2026-04-25genGeneration — pipeline-v5 · with 1 morepipeline-v5
  47. 2026-04-25rungeneration run

The same entries, as forms: six forms.