αMT
α-methyltryptamine
6Node page
what any key link opens
psx:substance/amt/section/pharmacology.full@1
sectionreferenced by edges — no row of its own
derived from · upstream
- informed_byClaim in pharmacology — supportedpsx:substance/amt/claim/b7e15848-0317-433a-a36d-35f77fc508e0
- informed_byClaim in pharmacology — supportedpsx:substance/amt/claim/418427c4-f4cd-438d-923b-f1ee7eb2468a
- informed_byClaim in pharmacology — supportedpsx:substance/amt/claim/bd0247ba-baad-4846-9e6e-0fc37a5f92ac
- informed_byClaim in pharmacology — supportedpsx:substance/amt/claim/ea701648-c981-4e78-a22a-937c592618cc
- informed_byClaim in pharmacology — supportedpsx:substance/amt/claim/c63e4711-7a26-4467-8cc7-15e13361a3b6
- informed_byClaim in pharmacology — inconclusivepsx:substance/amt/claim/6f730c06-7aab-4b75-8c4a-2ff1a68f8a3b
- informed_byClaim in pharmacology — supportedpsx:substance/amt/claim/323a5799-a2f4-49c5-a891-e269509455d7
- informed_byClaim in pharmacology — supportedpsx:substance/amt/claim/3e988bd4-e133-45d4-9982-958b8c84e390
feeds · downstream
none recorded
Closure of psx:substance/amt/section/pharmacology.full@1: 32 upstream, 33 downstream.
psx:substance/amt/section/pharmacology.full@1 ├─ informed_by claim/b7e15848-0317-433a-a36d-35f77fc508e0 Claim in pharmacology — supported ├─ informed_by claim/418427c4-f4cd-438d-923b-f1ee7eb2468a Claim in pharmacology — supported ├─ informed_by claim/bd0247ba-baad-4846-9e6e-0fc37a5f92ac Claim in pharmacology — supported ├─ informed_by claim/ea701648-c981-4e78-a22a-937c592618cc Claim in pharmacology — supported ├─ informed_by claim/c63e4711-7a26-4467-8cc7-15e13361a3b6 Claim in pharmacology — supported ├─ informed_by claim/6f730c06-7aab-4b75-8c4a-2ff1a68f8a3b Claim in pharmacology — inconclusive working ├─ informed_by claim/323a5799-a2f4-49c5-a891-e269509455d7 Claim in pharmacology — supported ├─ informed_by claim/3e988bd4-e133-45d4-9982-958b8c84e390 Claim in pharmacology — supported ├─ used src/doi:10.1016/j.toxlet.2017.03.007 In vitro monoamine oxidase inhibition potential of alpha-methyltryptamine analog new psychoactive substances for assessing possible toxic risks. ├─ used src/pmid:3091132 The effects of monoamine oxidase inhibitors on the ejaculatory response induced by 5-methoxy-N,N-dimethyltryptamine in the rat. ├─ used src/doi:10.1016/j.neures.2025.04.006 A systematic study of changes in monoamine neurotransmitters in the rat brain following acute administration of alpha-methyltryptamine (AMT), 5-methoxy-alpha-methyltryptamine (5-MeO-AMT) and 5-methoxy-N,N-diisopropyltryptamine (5-MeO-DiPT). ├─ used src/doi:10.1021/acschemneuro.5c00468 Dual Modulation of 5-HT2A Receptors and SERT by α-Ethyltryptamine and Its Optical Isomers. ├─ used src/doi:10.1097/FBP.0000000000000841 ├─ used src/doi:10.1007/s00204-015-1513-x The hallucinogenic world of tryptamines: an updated review. ├─ used src/doi:10.1007/s00204-020-02693-7 Designer drugs: mechanism of action and adverse effects ├─ used src/doi:10.3390/metabo13010092 Alpha-methyltryptamine (alpha-MT) Metabolite Profiling in Human Hepatocyte Incubations and Postmortem Urine and Blood ├─ used src/url:20cb97e3473fcc7c Alpha-methyltryptamine (Indopan) - NCATS Inxight Drugs ├─ used src/pmid:12678045 Schedules of controlled substances: temporary placement of alpha-methyltryptamine and 5-methoxy-N,N-diisopropyltryptamine into Schedule I. Final rule. ├─ used src/doi:10.1016/j.expneurol.2021.113638 New psychoactive substances (NPS) and serotonin syndrome onset: A systematic review. ├─ used src/doi:10.1021/acschemneuro.2c00170 Tolerance and Cross-Tolerance among Psychedelic and Nonpsychedelic 5-HT2A Receptor Agonists in Mice ├─ used src/doi:10.1016/j.bbr.2018.07.020 5-Methoxy-alpha-methyltryptamine (5-MeO-AMT), a tryptamine derivative, induces head-twitch responses in mice through the activation of serotonin receptor 2a in the prefrontal cortex. ├─ used src/url:3c1fc77ba0385127 AMT Drug Information - DrugWise ├─ used src/doi:10.2174/1570159X13666141210222409 ├─ used src/pmid:16105268 Fatality due to acute alpha-methyltryptamine intoxication. ├─ used src/pmid:15455477 Schedules of controlled substances: placement of alpha-methyltryptamine and 5-methoxy-N,N-diisopropyltryptamine into schedule I of the Controlled Substances Act. Final rule. ├─ used src/url:c29bc5afd23f85d7 Legal Status of Alpha-methyltryptamine - Multiple Jurisdictions ├─ used src/url:3ad72d5c592d8337 Release.org.uk - AMT Drug Information ├─ used src/doi:10.1007/s00213-021-05876-x Serotonin toxicity of serotonergic psychedelics ├─ used src/doi:10.1007/s00414-024-03236-w Alpha-methyltryptamine and 5-(2-methylaminopropyl)-benzofuran (5-MAPB) fatal co-intoxication: case report and review of literature ├─ used src/doi:10.3109/15563650.2014.885983 Patterns of presentation and clinical toxicity after reported use of alpha methyltryptamine in the United Kingdom. A report from the UK National Poisons Information Service. ├─ derived_from gen/fa205cf9-0ea6-4773-8b45-a7f571ae0dd9 Generation — pipeline-v5 └─ generated_by pub/793ed85a-cf09-4c5b-a475-4376fad1f033 Publication — backfill ├─ used version/1 Revision 1 ├─ used claim/0914056a-a5bc-43ed-94cb-26f65f6994da Claim in summary — partially_supported ├─ used claim/8c774afa-5b04-4340-b20a-210c04c1a045 Claim in safety — partially_supported ├─ used claim/5e3c02ae-da98-49f7-9206-ae67027acf63 Claim in safety — supported ├─ used claim/6b63dbcb-9efc-4326-bb37-263d3f309ec5 Claim in pharmacokinetic-detail — partially_supported ├─ used claim/a04c56e4-559a-4884-a789-4da63c2f2fdb Claim in summary — partially_supported ├─ used claim/3a7b820a-cc89-4ca2-9b00-5da84ae33326 Claim in neuroscience — supported ├─ used claim/f908de86-eec0-4ee2-9be6-717e35da37a5 Claim in chemistry — partially_supported ├─ used claim/fe144654-607b-4337-a5de-29d4d7255c5c Claim in receptor-pharmacology — partially_supported ├─ used claim/93850a31-26ea-4224-bb79-6f333eff9c03 Claim in comparative-pharmacology — partially_supported ├─ used claim/66a242f9-a9cc-4e18-b920-43b0e5967191 Claim in neuroscience — supported ├─ used claim/7fa5ba46-98f6-42fc-9c5d-1e64280dad5a Claim in summary — supported ├─ used claim/f97570f5-ca7f-4341-8c43-28827252248c Claim in safety — inconclusive working ├─ used claim/a7749afd-fff3-4fb4-a28b-d2fbd3fbe602 Claim in neuroscience — inconclusive working ├─ used claim/6ce627df-2f99-46ec-b055-f65fc6f7d4fe Claim in neuroscience — supported ├─ used claim/f2bf8b6a-1a74-4b53-94ff-663bf2cb019e Claim in history — supported ├─ used claim/71340da0-c9b1-4bae-9944-fee7dbf42f21 Claim in comparative-pharmacology — inconclusive working ├─ used claim/223a26f6-954e-4f37-87c0-057c5997b57e Claim in comparative-pharmacology — supported ├─ used claim/2d7d5a8e-f271-40c8-8805-8ade7aa8d113 Claim in pharmacokinetic-detail — supported ├─ derived_from issue/notice@76ddbaed5b37 Issued notice ├─ derived_from issue/info_card@46bc1bb853c0 Issued info_card ├─ derived_from issue/emergency@3f0909c25c71 Issued emergency ├─ derived_from issue/notice@a5727d1128c1 Issued notice ├─ derived_from issue/info_card@edd9e6b4fbff Issued info_card ├─ derived_from issue/emergency@c15c760aabf6 Issued emergency ├─ informed_by section/summary.full@1 ├─ informed_by section/safety.full@1 ├─ informed_by section/pharmacokinetic-detail.full@1 ├─ informed_by section/neuroscience.full@1 ├─ informed_by section/chemistry.full@1 ├─ informed_by section/receptor-pharmacology.full@1 ├─ informed_by section/comparative-pharmacology.full@1 └─ informed_by section/history.full@1 … closure truncated at 200 nodes
indented by distance from this node, not by parentage
1Provenance card
the boundary, as counts
2214 with DOI
3 strong · 13 moderate · 6 weak
0no compilation run
32last ruled 2026-06-04
0 awaiting a ruling
62026-10-19T20:30:37.413Z
notice · info card · emergency
171 with no results
queries and counts on the build
5444 supported
44 supported · 10 not
0received
consent field ships in Phase 4
196
derivations recorded for this entity
3Sources
22 consumed · sorted by year · feeds = sections resting on it
4Docket
one filing per activity — decisions, correspondence, reports
0012026-04-24revisionRevision 1
Initial LLM generation (v5 pipeline, wiki)
psx:substance/amt/version/10022026-06-04proposal30 value proposals approved together
one review action inferred from a shared reviewer and instant — the graph records one activity per proposal
psx:substance/amt/proposal/dose_tier/5daefdb4-dcbe-401b-b597-53e14f0c8e1230 items in this filing
- dose_tier · light
- dose_tier · common
- dose_tier · strong
- dose_tier · heavy
- timeline · oral · onset
- timeline · oral · come_up
- timeline · oral · peak
- timeline · oral · plateau
- timeline · oral · resolution
- timeline · oral · afterglow
- toxicity
- dependence · full
- withdrawal
- tolerance
- dosage · oral
- duration · oral · onset
- duration · oral · come_up
- duration · oral · peak
- duration · oral · offset
- duration · oral · total
- duration · oral · aftereffects
- contraindication · psychiatric
- contraindication · psychiatric
- contraindication · cardiovascular
- contraindication · cardiovascular
- contraindication · other
- contraindication · hepatic
- contraindication · pregnancy_breastfeeding
- contraindication · neurological
0032026-06-04publicationPublication — backfill
5Issued documents
what the notice, info card and emergency page said, by hash
| document | content hash | issued | from version | superseded |
|---|---|---|---|---|
| emergency | c15c760aabf6f0fcf5b6fc6b… | 2026-10-19 20:30 | Revision 1 | current |
| info_card | edd9e6b4fbffd1631569c3d6… | 2026-10-19 20:30 | Revision 1 | current |
| notice | a5727d1128c1dace6c07efd9… | 2026-10-19 20:30 | Revision 1 | current |
| emergency | 3f0909c25c714d225b4bb3e3… | 2026-09-04 04:28 | Revision 1 | superseded2026-10-19 |
| info_card | 46bc1bb853c085bd0b8092e6… | 2026-09-04 04:28 | Revision 1 | superseded2026-10-19 |
| notice | 76ddbaed5b3762d419832d3d… | 2026-09-04 04:28 | Revision 1 | superseded2026-10-19 |