αMT
α-methyltryptamine
6Node page
what any key link opens
psx:substance/amt/section/clinical-evidence.full@1
sectionreferenced by edges — no row of its own
derived from · upstream
- informed_byClaim in clinical-evidence — partially_supportedpsx:substance/amt/claim/e31b36b3-bb42-4df1-aa5d-718175da24cd
feeds · downstream
none recorded
Closure of psx:substance/amt/section/clinical-evidence.full@1: 25 upstream, 9 downstream.
psx:substance/amt/section/clinical-evidence.full@1 ├─ informed_by claim/e31b36b3-bb42-4df1-aa5d-718175da24cd Claim in clinical-evidence — partially_supported ├─ used src/pmid:15455477 Schedules of controlled substances: placement of alpha-methyltryptamine and 5-methoxy-N,N-diisopropyltryptamine into schedule I of the Controlled Substances Act. Final rule. ├─ used src/url:20cb97e3473fcc7c Alpha-methyltryptamine (Indopan) - NCATS Inxight Drugs ├─ used src/pmid:12678045 Schedules of controlled substances: temporary placement of alpha-methyltryptamine and 5-methoxy-N,N-diisopropyltryptamine into Schedule I. Final rule. ├─ used src/doi:10.1016/j.toxlet.2017.03.007 In vitro monoamine oxidase inhibition potential of alpha-methyltryptamine analog new psychoactive substances for assessing possible toxic risks. ├─ used src/doi:10.1016/j.neures.2025.04.006 A systematic study of changes in monoamine neurotransmitters in the rat brain following acute administration of alpha-methyltryptamine (AMT), 5-methoxy-alpha-methyltryptamine (5-MeO-AMT) and 5-methoxy-N,N-diisopropyltryptamine (5-MeO-DiPT). ├─ used src/doi:10.1097/FBP.0000000000000841 ├─ used src/doi:10.1016/j.expneurol.2021.113638 New psychoactive substances (NPS) and serotonin syndrome onset: A systematic review. ├─ used src/doi:10.1021/acschemneuro.2c00170 Tolerance and Cross-Tolerance among Psychedelic and Nonpsychedelic 5-HT2A Receptor Agonists in Mice ├─ used src/doi:10.1016/j.bbr.2018.07.020 5-Methoxy-alpha-methyltryptamine (5-MeO-AMT), a tryptamine derivative, induces head-twitch responses in mice through the activation of serotonin receptor 2a in the prefrontal cortex. ├─ used src/url:3c1fc77ba0385127 AMT Drug Information - DrugWise ├─ used src/doi:10.1007/s00204-015-1513-x The hallucinogenic world of tryptamines: an updated review. ├─ used src/doi:10.2174/1570159X13666141210222409 ├─ used src/pmid:16105268 Fatality due to acute alpha-methyltryptamine intoxication. ├─ used src/url:c29bc5afd23f85d7 Legal Status of Alpha-methyltryptamine - Multiple Jurisdictions ├─ used src/doi:10.1021/acschemneuro.5c00468 Dual Modulation of 5-HT2A Receptors and SERT by α-Ethyltryptamine and Its Optical Isomers. ├─ used src/url:3ad72d5c592d8337 Release.org.uk - AMT Drug Information ├─ used src/pmid:3091132 The effects of monoamine oxidase inhibitors on the ejaculatory response induced by 5-methoxy-N,N-dimethyltryptamine in the rat. ├─ used src/doi:10.1007/s00204-020-02693-7 Designer drugs: mechanism of action and adverse effects ├─ used src/doi:10.3390/metabo13010092 Alpha-methyltryptamine (alpha-MT) Metabolite Profiling in Human Hepatocyte Incubations and Postmortem Urine and Blood ├─ used src/doi:10.1007/s00213-021-05876-x Serotonin toxicity of serotonergic psychedelics ├─ used src/doi:10.1007/s00414-024-03236-w Alpha-methyltryptamine and 5-(2-methylaminopropyl)-benzofuran (5-MAPB) fatal co-intoxication: case report and review of literature ├─ used src/doi:10.3109/15563650.2014.885983 Patterns of presentation and clinical toxicity after reported use of alpha methyltryptamine in the United Kingdom. A report from the UK National Poisons Information Service. ├─ derived_from gen/fa205cf9-0ea6-4773-8b45-a7f571ae0dd9 Generation — pipeline-v5 └─ generated_by pub/793ed85a-cf09-4c5b-a475-4376fad1f033 Publication — backfill ├─ used version/1 Revision 1 ├─ used claim/36375afe-9233-478c-8704-c978a7e3d10b Claim in history — partially_supported ├─ derived_from issue/notice@76ddbaed5b37 Issued notice ├─ derived_from issue/info_card@46bc1bb853c0 Issued info_card ├─ derived_from issue/emergency@3f0909c25c71 Issued emergency ├─ derived_from issue/notice@a5727d1128c1 Issued notice ├─ derived_from issue/info_card@edd9e6b4fbff Issued info_card ├─ derived_from issue/emergency@c15c760aabf6 Issued emergency └─ informed_by section/history.full@1 … closure truncated at 200 nodes
indented by distance from this node, not by parentage
1Provenance card
the boundary, as counts
2214 with DOI
3 strong · 13 moderate · 6 weak
0no compilation run
32last ruled 2026-06-04
0 awaiting a ruling
62026-10-19T20:30:37.413Z
notice · info card · emergency
171 with no results
queries and counts on the build
5444 supported
44 supported · 10 not
0received
consent field ships in Phase 4
196
derivations recorded for this entity
3Sources
22 consumed · sorted by year · feeds = sections resting on it
4Docket
one filing per activity — decisions, correspondence, reports
0012026-04-24revisionRevision 1
Initial LLM generation (v5 pipeline, wiki)
psx:substance/amt/version/10022026-06-04proposal30 value proposals approved together
one review action inferred from a shared reviewer and instant — the graph records one activity per proposal
psx:substance/amt/proposal/dose_tier/5daefdb4-dcbe-401b-b597-53e14f0c8e1230 items in this filing
- dose_tier · light
- dose_tier · common
- dose_tier · strong
- dose_tier · heavy
- timeline · oral · onset
- timeline · oral · come_up
- timeline · oral · peak
- timeline · oral · plateau
- timeline · oral · resolution
- timeline · oral · afterglow
- toxicity
- dependence · full
- withdrawal
- tolerance
- dosage · oral
- duration · oral · onset
- duration · oral · come_up
- duration · oral · peak
- duration · oral · offset
- duration · oral · total
- duration · oral · aftereffects
- contraindication · psychiatric
- contraindication · psychiatric
- contraindication · cardiovascular
- contraindication · cardiovascular
- contraindication · other
- contraindication · hepatic
- contraindication · pregnancy_breastfeeding
- contraindication · neurological
0032026-06-04publicationPublication — backfill
5Issued documents
what the notice, info card and emergency page said, by hash
| document | content hash | issued | from version | superseded |
|---|---|---|---|---|
| emergency | c15c760aabf6f0fcf5b6fc6b… | 2026-10-19 20:30 | Revision 1 | current |
| info_card | edd9e6b4fbffd1631569c3d6… | 2026-10-19 20:30 | Revision 1 | current |
| notice | a5727d1128c1dace6c07efd9… | 2026-10-19 20:30 | Revision 1 | current |
| emergency | 3f0909c25c714d225b4bb3e3… | 2026-09-04 04:28 | Revision 1 | superseded2026-10-19 |
| info_card | 46bc1bb853c085bd0b8092e6… | 2026-09-04 04:28 | Revision 1 | superseded2026-10-19 |
| notice | 76ddbaed5b3762d419832d3d… | 2026-09-04 04:28 | Revision 1 | superseded2026-10-19 |