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4-HO-DiPT

4-hydroxy-N,N-diisopropyltryptamine

1Provenance card

the boundary, as counts

Sources

2216 with DOI

4 strong · 12 moderate · 6 weak

Compilations

12026-04-26T14:55:21.968Z

pipeline-v5 · prompt hash not recorded — run predates 2026-09

Decisions

30last ruled 2026-06-04

0 awaiting a ruling

Issued documents

62026-10-19T20:29:57.389Z

notice · info card · emergency

Searches

193 with no results

queries and counts on the build

Claims checked

5135 supported

35 supported · 16 not

Correspondence

0received

consent field ships in Phase 4

Edges

190

derivations recorded for this entity

Complete over 22 sources, 1 compilation, and 30 decisions.Not here: the private journal (never).Working material — drafts, discards, unsupported claims — is listed below and readable on the working page.Cite: psychedex.org/substances/4-ho-dipt/archive

Timeline

what happened, newest first — claims, searches and artifacts stay inside Build

  1. 2026-10-19issueIssued emergency
  2. 2026-10-19issueIssued info_card
  3. 2026-10-19issueIssued notice
  4. 2026-09-24srcMetabolism of the tryptamine-derived new psychoactive substances 5-MeO-2-Me-DALT, 5-MeO-2-Me-ALCHT, and 5-MeO-2-Me-DIPT and their detectability in urine
  5. 2026-09-24srcPsilocin analogs. 1. Synthesis of 3-[2-(dialkylamino)ethyl]-and 3-[2-(cycloalkylamino)ethyl] indol-4-ols
  6. 2026-09-24srcOpioid analgesic drugs and serotonin toxicity (syndrome): mechanisms, animal models, and links to clinical effects
  7. 2026-09-24srcDesigner drugs: mechanism of action and adverse effects
  8. 2026-09-24srcReceptor interaction profiles of novel psychoactive tryptamines compared with classic hallucinogens
  9. 2026-09-24srcRE104: Synthesis and Activity of a Novel Serotonergic Psychedelic Prodrug of 4-Hydroxy-N,N-diisopropyltryptamine
  10. 2026-09-24srcInvestigation of the Structure-Activity Relationships of Psilocybin Analogues
  11. 2026-09-24srcReceptor Binding Profiles for Tryptamine Psychedelics and Effects of 4-Propionoxy-N,N-dimethyltryptamine in Mice
  12. 2026-09-24srcPsilocybin analog 4-OH-DiPT enhances fear extinction and GABAergic inhibition of principal neurons in the basolateral amygdala
  13. 2026-09-24srcPsychedelics promote plasticity by directly binding to BDNF receptor TrkB
  14. 2026-09-24srcSynthesis and structure of 4-hydroxy-N-isopropyltryptamine (4-HO-NiPT) and its precursors
  15. 2026-09-24srcBenefits and Challenges of Ultra-Fast, Short-Acting Psychedelics in the Treatment of Depression
  16. 2026-09-24srcIndolealkylamines: biotransformations and potential drug-drug interactions
  17. 2026-09-24srcRecreational use, analysis and toxicity of tryptamines.
  18. 2026-09-24srcHuman Hepatocyte 4-Acetoxy-N,N-Diisopropyltryptamine Metabolite Profiling by LC-HRMS/MS
  19. 2026-09-24srcMultimechanistic Single-Entity Combinations for Chronic Pain Control: A Narrative Review.
  20. 2026-09-24srcSchedules of Controlled Substances: Placement of 4-hydroxy-N,N-diisopropyltryptamine — Withdrawal of Proposed Rule
  21. 2026-09-24src4-Hydroxy-N,N-diisopropyltryptamine - Wikipedia
  22. 2026-09-24srcPharmacologic Activity Review: 4-HO-DiPT
  23. 2026-09-24srcRE104 Safety and Efficacy Study in Postpartum Depression (RECONNECT)
  24. 2026-09-24srcU.S. FDA Grants Reunion Neuroscience's Luvesilocin (RE104) Breakthrough Therapy Designation Status
  25. 2026-09-24srcTiHKAL #17: 4-HO-DIPT
  26. 2026-09-04issueIssued emergency
  27. 2026-09-04issueIssued info_card
  28. 2026-09-04issueIssued notice
  29. 2026-06-04proposal28 value proposals approved togetherone review action inferred from a shared reviewer and instant — the graph records one activity per proposal
  30. 2026-06-04publicationPublication — backfill
  31. 2026-04-26revisionRevision 1
  32. 2026-04-26absenceSearched PubMed for "4-hydroxy-N-isopropyltryptamine 4-HO-NiPT synthesis structure metabolite tryptamine" — no results
  33. 2026-04-26absenceSearched PubMed for "4-hydroxy diisopropyltryptamine serotonin receptor binding pharmacology" — no results
  34. 2026-04-26absenceSearched ClinicalTrials.gov for "4-HO-DiPT diisopropyltryptamine" — no results
  35. 2026-04-26genGeneration — pipeline-v5pipeline-v5
  36. 2026-04-26rungeneration run

The same entries, as forms: six forms.