Skip to main content
Psychedex

1Provenance card

the boundary, as counts

Sources

2617 with DOI

9 strong · 12 moderate · 5 weak

Compilations

12026-04-26T13:37:08.940Z

pipeline-v5 · prompt hash not recorded — run predates 2026-09

Decisions

31last ruled 2026-06-04

0 awaiting a ruling

Issued documents

62026-10-19T20:29:56.278Z

notice · info card · emergency

Searches

202 with no results

queries and counts on the build

Claims checked

6443 supported

43 supported · 21 not

Correspondence

0received

consent field ships in Phase 4

Edges

222

derivations recorded for this entity

Complete over 26 sources, 1 compilation, and 31 decisions.Not here: the private journal (never).Working material — drafts, discards, unsupported claims — is listed below and readable on the working page.Cite: psychedex.org/substances/4-ho-det/archive

Timeline

what happened, newest first — claims, searches and artifacts stay inside Build

  1. 2026-10-19issueIssued emergency
  2. 2026-10-19issueIssued info_card
  3. 2026-10-19issueIssued notice
  4. 2026-09-24srcChemistry and Structure-Activity Relationships of Psychedelics.
  5. 2026-09-24srcOpioid analgesic drugs and serotonin toxicity (syndrome): mechanisms, animal models, and links to clinical effects
  6. 2026-09-24srcIn Vitro Structure-Activity Relationship of 30 Psychedelic NPS by β-Arrestin 2 Recruitment to 5-HT2A Receptor
  7. 2026-09-24srcHallucinogen persisting perception disorder and the serotonergic system: a comprehensive review including new MDMA-related clinical cases
  8. 2026-09-24srcTolerance and Cross-Tolerance among Psychedelic and Nonpsychedelic 5-HT2A Receptor Agonists in Mice
  9. 2026-09-24srcDiscriminative Stimulus Effects of Substituted Tryptamines in Rats
  10. 2026-09-24srcReceptor Binding Profiles for Tryptamine Psychedelics and Effects of 4-Propionoxy-N,N-dimethyltryptamine in Mice
  11. 2026-09-24srcMechanisms and Molecular Targets Surrounding the Potential Therapeutic Effects of Psychedelics
  12. 2026-09-24srcThe History of Psychedelics in Psychiatry
  13. 2026-09-24srcClassic Psychedelic Drugs: Update on Biological Mechanisms
  14. 2026-09-24srcN,N-Dimethyltryptamine Forms Oxygenated Metabolites via CYP2D6 - An In Vitro Investigation
  15. 2026-09-24srcDifferential contributions of serotonin receptors to the behavioral effects of indoleamine hallucinogens in mice
  16. 2026-09-24srcDrug-drug interactions involving classic psychedelics: A systematic review
  17. 2026-09-24srcSerotonin syndrome: is it a reason to avoid the use of tramadol with antidepressants?
  18. 2026-09-24srcLower-Dose Psycholytic Therapy - A Neglected Approach
  19. 2026-09-24srcRole of 5-HT2A, 5-HT2C, 5-HT1A and TAAR1 Receptors in the Head Twitch Response Induced by 5-HTP and Psilocybin
  20. 2026-09-24srcPharmacokinetics of Psilocybin: A Systematic Review
  21. 2026-09-24srcFurther Studies on Oxygenated Tryptamines with LSD-Like Activity Incorporating a Chiral Pyrrolidine Moiety
  22. 2026-09-24src5-HT2A Receptor-Stimulated Phosphoinositide Hydrolysis in the Stimulus Effects of Hallucinogens
  23. 2026-09-24srcHallucinogen Persisting Perception Disorder After Psilocybin Consumption: A Case Study
  24. 2026-09-24srcLysergic acid diethylamide (LSD) administration selectively downregulates serotonin2 receptors in rat brain
  25. 2026-09-24srcDetermination of psilocin and 4-hydroxyindole-3-acetic acid in plasma by HPLC-ECD and pharmacokinetic profiles of oral and intravenous psilocybin in man
  26. 2026-09-24src4-HO-DET - WikiDoc
  27. 2026-09-24srcPubChem Compound: 4-HO-DET (CID 9991554)
  28. 2026-09-24srcTiHKAL: Tryptamines I Have Known And Loved - Entry #16: 4-HO-DET
  29. 2026-09-24src4-HO-DET - Wikipedia
  30. 2026-09-04issueIssued emergency
  31. 2026-09-04issueIssued info_card
  32. 2026-09-04issueIssued notice
  33. 2026-06-04proposal29 value proposals approved togetherone review action inferred from a shared reviewer and instant — the graph records one activity per proposal
  34. 2026-06-04publicationPublication — backfill
  35. 2026-04-26revisionRevision 1
  36. 2026-04-26absenceSearched ClinicalTrials.gov for "4-HO-DET diethyltryptamine psychedelic" — no results
  37. 2026-04-26absenceSearched ClinicalTrials.gov for "4-HO-DET diethyltryptamine psychedelic" — no results
  38. 2026-04-26genGeneration — pipeline-v5pipeline-v5
  39. 2026-04-26rungeneration run

The same entries, as forms: six forms.