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Psychedex

4-AcO-MET

4-acetoxy-N-methyl-N-ethyltryptamine

1Provenance card

the boundary, as counts

Sources

1714 with DOI

2 strong · 12 moderate · 3 weak

Compilations

12026-04-26T12:49:03.299Z

pipeline-v5 · prompt hash not recorded — run predates 2026-09

Decisions

31last ruled 2026-06-04

0 awaiting a ruling

Issued documents

62026-10-19T20:29:51.174Z

notice · info card · emergency

Searches

192 with no results

queries and counts on the build

Claims checked

4836 supported

36 supported · 12 not

Correspondence

0received

consent field ships in Phase 4

Edges

180

derivations recorded for this entity

Complete over 17 sources, 1 compilation, and 31 decisions.Not here: the private journal (never).Working material — drafts, discards, unsupported claims — is listed below and readable on the working page.Cite: psychedex.org/substances/4-aco-met/archive

Timeline

what happened, newest first — claims, searches and artifacts stay inside Build

  1. 2026-10-19issueIssued emergency
  2. 2026-10-19issueIssued info_card
  3. 2026-10-19issueIssued notice
  4. 2026-09-24srcTentative identification of in vitro metabolites of O-acetylpsilocin (psilacetin, 4-AcO-DMT) by UHPLC-Q-Orbitrap MS
  5. 2026-09-24srcOpioid analgesic drugs and serotonin toxicity (syndrome): mechanisms, animal models, and links to clinical effects
  6. 2026-09-24srcIn-silico toxicity study of tryptamine, psilocin, psilocybin, N,N-dimethyltryptamine, 5'-methoxy-N,N-dimethyltryptamine and O-acetylpsilocin
  7. 2026-09-24srcPsychedelic-related deaths in England, Wales and Northern Ireland (1997-2022)
  8. 2026-09-24srcTolerance and Cross-Tolerance among Psychedelic and Nonpsychedelic 5-HT2A Receptor Agonists in Mice
  9. 2026-09-24srcReceptor Binding Profiles for Tryptamine Psychedelics and Effects of 4-Propionoxy-N,N-dimethyltryptamine in Mice
  10. 2026-09-24srcA Fatality Related to Two Novel Hallucinogenic Compounds: 4-Methoxyphencyclidine and 4-Hydroxy-N-methyl-N-ethyltryptamine
  11. 2026-09-24srcPsilacetin derivatives: fumarate salts of the methyl-ethyl, methyl-allyl and diallyl variants of the psilocin prodrug
  12. 2026-09-24srcPharmacologic Activity of Substituted Tryptamines at 5-HT2A, 5-HT2C, 5-HT1A Receptors and SERT
  13. 2026-09-24srcAdverse effects of psychedelics: From anecdotes and misinformation to systematic science
  14. 2026-09-24srcIdentification of New Psychoactive Tryptamines 4-OH-MET and 4-AcO-DMT Using High Resolution Mass Spectrometry and Nuclear Magnetic Resonance Spectroscopy
  15. 2026-09-24srcTherapeutic use of psilocybin: Practical considerations for dosing and administration
  16. 2026-09-24srcToxicology and Analysis of Psychoactive Tryptamines.
  17. 2026-09-24srcHuman Hepatocyte 4-Acetoxy-N,N-Diisopropyltryptamine Metabolite Profiling by LC-HRMS/MS
  18. 2026-09-24srcDifferential interactions of indolealkylamines with 5-hydroxytryptamine receptor subtypes
  19. 2026-09-24srcTiHKAL #21: 4-HO-MET (Erowid online reproduction)
  20. 2026-09-24src4-AcO-MET (HandWiki)
  21. 2026-09-04issueIssued emergency
  22. 2026-09-04issueIssued info_card
  23. 2026-09-04issueIssued notice
  24. 2026-06-04proposal29 value proposals approved togetherone review action inferred from a shared reviewer and instant — the graph records one activity per proposal
  25. 2026-06-04publicationPublication — backfill
  26. 2026-04-26revisionRevision 1
  27. 2026-04-26absenceSearched ClinicalTrials.gov for "4-AcO-MET tryptamine psychedelic" — no results
  28. 2026-04-26absenceSearched PubMed for "4-AcO-MET 4-acetoxy-MET tryptamine psychedelic" — no results
  29. 2026-04-26genGeneration — pipeline-v5pipeline-v5
  30. 2026-04-26rungeneration run

The same entries, as forms: six forms.