3C-E
4-ethoxy-3,5-dimethoxyamphetamine
1Provenance card
the boundary, as counts
Sources
2215 with DOI
2 strong · 16 moderate · 4 weak
Compilations
12026-05-11T03:55:30.366Z
pipeline-v5 · prompt hash not recorded — run predates 2026-09
Decisions
39last ruled 2026-06-04
0 awaiting a ruling
Issued documents
62026-10-19T20:29:45.759Z
notice · info card · emergency
Searches
212 with no results
queries and counts on the build
Claims checked
5346 supported
46 supported · 7 not
Correspondence
0received
consent field ships in Phase 4
Edges
205
derivations recorded for this entity
Complete over 22 sources, 1 compilation, and 39 decisions.Not here: the private journal (never).Working material — drafts, discards, unsupported claims — is listed below and readable on the working page.Cite: psychedex.org/substances/3c-e/archive
Timeline
what happened, newest first — claims, searches and artifacts stay inside Build
- 2026-10-19issueIssued emergency
- 2026-10-19issueIssued info_card
- 2026-10-19issueIssued notice
- 2026-09-07srcChemistry and Structure-Activity Relationships of Psychedelics.
- 2026-09-07srcFlashbacks, Hallucinogen Persisting Perception Disorder (HPPD), and Reactivations Following the Use of Classic Psychedelics: Classification and Therapeutic Management
- 2026-09-07srcOpioid analgesic drugs and serotonin toxicity (syndrome): mechanisms, animal models, and links to clinical effects
- 2026-09-07srcDesigner drugs: mechanism of action and adverse effects
- 2026-09-07srcHallucinogens as discriminative stimuli in animals: LSD, phenethylamines, and tryptamines.
- 2026-09-07src5-hydroxytryptamine- and dopamine-releasing effects of ring-substituted amphetamines on rat brain: a comparative study using in vivo microdialysis
- 2026-09-07srcRole of the 5-HT2A receptor in the locomotor hyperactivity produced by phenylalkylamine hallucinogens in mice
- 2026-09-07srcCorrelation between the potency of hallucinogens in the mouse head-twitch response assay and their behavioral and subjective effects in other species
- 2026-09-07srcMescaline: The forgotten psychedelic
- 2026-09-07src2,5-Dimethoxyamphetamine-derived designer drugs: studies on the identification of cytochrome P450 (CYP) isoenzymes involved in formation of their main metabolites and on their capability to inhibit CYP2D6.
- 2026-09-07srcInvestigation of the 2,5-Dimethoxy Motif in Phenethylamine Serotonin 2A Receptor Agonists
- 2026-09-07srcTolerance and Cross-Tolerance among Psychedelic and Nonpsychedelic 5-HT2A Receptor Agonists in Mice
- 2026-09-07srcComparison of the behavioral effects of mescaline analogs using the head twitch response in mice
- 2026-09-07srcPeakAL: Protons I Have Known and Loved — NMR spectra of psychedelic phenylethanamines including TMA-2
- 2026-09-07srcReceptor Interaction Profiles of 4-Alkoxy-Substituted 2,5-Dimethoxyphenethylamines and Related Amphetamines.
- 2026-09-07srcDifferential phospholipase C activation by phenylalkylamine serotonin 5-HT2A receptor agonists
- 2026-09-07srcLysergic acid diethylamide (LSD) administration selectively downregulates serotonin2 receptors in rat brain
- 2026-09-07srcEffect of a chiral 4-alkyl substituent in hallucinogenic amphetamines.
- 2026-09-07srcDihydrobenzofuran analogues of hallucinogens. 4. Mescaline derivatives
- 2026-09-07src3C-E chemical and pharmacological data
- 2026-09-07srcPiHKAL Entry #25: 3C-E (3,5-Dimethoxy-4-Ethoxyamphetamine)
- 2026-09-07src3C-E legal status and scheduling
- 2026-09-04issueIssued emergency
- 2026-09-04issueIssued info_card
- 2026-09-04issueIssued notice
- 2026-06-04proposal37 value proposals approved togetherone review action inferred from a shared reviewer and instant — the graph records one activity per proposal
- 2026-06-04publicationPublication — backfill
- 2026-05-11revisionRevision 1
- 2026-05-11absenceSearched ClinicalTrials.gov for "3C-E mescaline analog phenethylamine psychedelic" — no results
- 2026-05-11absenceSearched PubMed for "3C-E 1-(4-ethoxy-3,5-dimethoxyphenyl)propan-2-amine psychedelic phenethylamine" — no results
- 2026-05-11genGeneration — pipeline-v5 · with 4 morepipeline-v5
- 2026-05-11rungeneration run
The same entries, as forms: six forms.