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1Provenance card

the boundary, as counts

Sources

2215 with DOI

2 strong · 16 moderate · 4 weak

Compilations

12026-05-11T03:55:30.366Z

pipeline-v5 · prompt hash not recorded — run predates 2026-09

Decisions

39last ruled 2026-06-04

0 awaiting a ruling

Issued documents

62026-10-19T20:29:45.759Z

notice · info card · emergency

Searches

212 with no results

queries and counts on the build

Claims checked

5346 supported

46 supported · 7 not

Correspondence

0received

consent field ships in Phase 4

Edges

205

derivations recorded for this entity

Complete over 22 sources, 1 compilation, and 39 decisions.Not here: the private journal (never).Working material — drafts, discards, unsupported claims — is listed below and readable on the working page.Cite: psychedex.org/substances/3c-e/archive

Timeline

what happened, newest first — claims, searches and artifacts stay inside Build

  1. 2026-10-19issueIssued emergency
  2. 2026-10-19issueIssued info_card
  3. 2026-10-19issueIssued notice
  4. 2026-09-07srcChemistry and Structure-Activity Relationships of Psychedelics.
  5. 2026-09-07srcFlashbacks, Hallucinogen Persisting Perception Disorder (HPPD), and Reactivations Following the Use of Classic Psychedelics: Classification and Therapeutic Management
  6. 2026-09-07srcOpioid analgesic drugs and serotonin toxicity (syndrome): mechanisms, animal models, and links to clinical effects
  7. 2026-09-07srcDesigner drugs: mechanism of action and adverse effects
  8. 2026-09-07srcHallucinogens as discriminative stimuli in animals: LSD, phenethylamines, and tryptamines.
  9. 2026-09-07src5-hydroxytryptamine- and dopamine-releasing effects of ring-substituted amphetamines on rat brain: a comparative study using in vivo microdialysis
  10. 2026-09-07srcRole of the 5-HT2A receptor in the locomotor hyperactivity produced by phenylalkylamine hallucinogens in mice
  11. 2026-09-07srcCorrelation between the potency of hallucinogens in the mouse head-twitch response assay and their behavioral and subjective effects in other species
  12. 2026-09-07srcMescaline: The forgotten psychedelic
  13. 2026-09-07src2,5-Dimethoxyamphetamine-derived designer drugs: studies on the identification of cytochrome P450 (CYP) isoenzymes involved in formation of their main metabolites and on their capability to inhibit CYP2D6.
  14. 2026-09-07srcInvestigation of the 2,5-Dimethoxy Motif in Phenethylamine Serotonin 2A Receptor Agonists
  15. 2026-09-07srcTolerance and Cross-Tolerance among Psychedelic and Nonpsychedelic 5-HT2A Receptor Agonists in Mice
  16. 2026-09-07srcComparison of the behavioral effects of mescaline analogs using the head twitch response in mice
  17. 2026-09-07srcPeakAL: Protons I Have Known and Loved — NMR spectra of psychedelic phenylethanamines including TMA-2
  18. 2026-09-07srcReceptor Interaction Profiles of 4-Alkoxy-Substituted 2,5-Dimethoxyphenethylamines and Related Amphetamines.
  19. 2026-09-07srcDifferential phospholipase C activation by phenylalkylamine serotonin 5-HT2A receptor agonists
  20. 2026-09-07srcLysergic acid diethylamide (LSD) administration selectively downregulates serotonin2 receptors in rat brain
  21. 2026-09-07srcEffect of a chiral 4-alkyl substituent in hallucinogenic amphetamines.
  22. 2026-09-07srcDihydrobenzofuran analogues of hallucinogens. 4. Mescaline derivatives
  23. 2026-09-07src3C-E chemical and pharmacological data
  24. 2026-09-07srcPiHKAL Entry #25: 3C-E (3,5-Dimethoxy-4-Ethoxyamphetamine)
  25. 2026-09-07src3C-E legal status and scheduling
  26. 2026-09-04issueIssued emergency
  27. 2026-09-04issueIssued info_card
  28. 2026-09-04issueIssued notice
  29. 2026-06-04proposal37 value proposals approved togetherone review action inferred from a shared reviewer and instant — the graph records one activity per proposal
  30. 2026-06-04publicationPublication — backfill
  31. 2026-05-11revisionRevision 1
  32. 2026-05-11absenceSearched ClinicalTrials.gov for "3C-E mescaline analog phenethylamine psychedelic" — no results
  33. 2026-05-11absenceSearched PubMed for "3C-E 1-(4-ethoxy-3,5-dimethoxyphenyl)propan-2-amine psychedelic phenethylamine" — no results
  34. 2026-05-11genGeneration — pipeline-v5 · with 4 morepipeline-v5
  35. 2026-05-11rungeneration run

The same entries, as forms: six forms.