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25C-NBOMe

4-chloro-2,5-dimethoxy-N-(2-methoxybenzyl)phenethylamine

1Provenance card

the boundary, as counts

Sources

2722 with DOI

3 strong · 19 moderate · 5 weak

Compilations

12026-04-28T06:37:16.441Z

pipeline-v5 · prompt hash not recorded — run predates 2026-09

Decisions

31last ruled 2026-06-04

0 awaiting a ruling

Issued documents

62026-10-19T20:29:07.697Z

notice · info card · emergency

Searches

171 with no results

queries and counts on the build

Claims checked

8855 supported

55 supported · 33 not

Correspondence

0received

consent field ships in Phase 4

Edges

268

derivations recorded for this entity

Complete over 27 sources, 1 compilation, and 31 decisions.Not here: the private journal (never).Working material — drafts, discards, unsupported claims — is listed below and readable on the working page.Cite: psychedex.org/substances/25c-nbome/archive

Timeline

what happened, newest first — claims, searches and artifacts stay inside Build

  1. 2026-10-19issueIssued emergency
  2. 2026-10-19issueIssued info_card
  3. 2026-10-19issueIssued notice
  4. 2026-09-24srcIn vitro characterization of potential CYP- and UGT-derived metabolites of the psychoactive drug 25B-NBOMe using LC-high resolution MS.
  5. 2026-09-24srcPharmacology and Toxicology of N-Benzylphenethylamine (NBOMe) Hallucinogens
  6. 2026-09-24srcDesigner drugs: mechanism of action and adverse effects
  7. 2026-09-24src25I-NBOMe: clinical case with unique confirmatory testing
  8. 2026-09-24srcIdentification of psychedelic new psychoactive substances (NPS) showing biased agonism at the 5-HT2AR through simultaneous use of β-arrestin 2 and miniGαq bioassays
  9. 2026-09-24srcA fatal poisoning involving 25C-NBOMe.
  10. 2026-09-24srcMetabolic characterization of 25X-NBOH and 25X-NBOMe phenethylamines based on UHPLC-Q-Exactive Orbitrap MS in human liver microsomes.
  11. 2026-09-24srcReceptor interaction profiles of novel N-2-methoxybenzyl (NBOMe) derivatives of 2,5-dimethoxy-substituted phenethylamines (2C drugs)
  12. 2026-09-24srcComparative neuropharmacology of N-(2-methoxybenzyl)-2,5-dimethoxyphenethylamine (NBOMe) hallucinogens and their 2C counterparts in male rats
  13. 2026-09-24srcToxicities associated with NBOMe ingestion-a novel class of potent hallucinogens: a review of the literature.
  14. 2026-09-24srcNew psychoactive substances: Studies on the metabolism of XLR-11, AB-PINACA, FUB-PB-22, 4-methoxy-a-PVP, 25-I-NBOMe, and meclonazepam using human liver preparations.
  15. 2026-09-24srcTolerance and Cross-Tolerance among Psychedelic and Nonpsychedelic 5-HT2A Receptor Agonists in Mice
  16. 2026-09-24srcN-Benzyl-5-methoxytryptamines as Potent Serotonin 5-HT2 Receptor Family Agonists and Comparison with a Series of Phenethylamine Analogues
  17. 2026-09-24srcIdentification of 5-HT2A receptor signaling pathways associated with psychedelic potential
  18. 2026-09-24srcAnalysis of 25I-NBOMe, 25B-NBOMe, 25C-NBOMe and Other Dimethoxyphenyl-N-[(2-Methoxyphenyl)Methyl]Ethanamine Derivatives on Blotter Paper.
  19. 2026-09-24srcMetabolic Profile Determination of NBOMe Compounds Using Human Liver Microsomes and Comparison with Findings in Authentic Human Blood and Urine.
  20. 2026-09-24src25C-NBOMe: Preliminary Data on Pharmacology, Psychoactive Effects, and Toxicity of a New Potent and Dangerous Hallucinogenic Drug
  21. 2026-09-24srcRadiosynthesis and Evaluation of 11C-CIMBI-5 as a 5-HT2A Receptor Agonist Radioligand for PET.
  22. 2026-09-24srcTwo cases of severe intoxication associated with analytically confirmed use of the novel psychoactive substances 25B-NBOMe and 25C-NBOMe.
  23. 2026-09-24srcCase series: toxicity from 25B-NBOMe--a cluster of N-bomb cases.
  24. 2026-09-24srcNBOMes-Highly Potent and Toxic Alternatives of LSD
  25. 2026-09-24srcAcute pharmacological profile of 2C-B-Fly-NBOMe in male Wistar rats-pharmacokinetics, effects on behaviour and thermoregulation
  26. 2026-09-24srcLysergic acid diethylamide (LSD) administration selectively downregulates serotonin2 receptors in rat brain
  27. 2026-09-24srcSchedules of controlled substances: temporary placement of three synthetic phenethylamines into Schedule I. Final order.
  28. 2026-09-24srcNBOMe: new potent hallucinogens--pharmacology, analytical methods, toxicities, fatalities: a review
  29. 2026-09-24srcSchedules of Controlled Substances: Extension of Temporary Placement of Three Synthetic Phenethylamines in Schedule I. Final order.
  30. 2026-09-24src25C-NBOMe legal status: UK Class A, Canada Schedule III, Russia, Brazil, Israel, Sweden, US State scheduling
  31. 2026-09-04issueIssued emergency
  32. 2026-09-04issueIssued info_card
  33. 2026-09-04issueIssued notice
  34. 2026-06-04proposal29 value proposals approved togetherone review action inferred from a shared reviewer and instant — the graph records one activity per proposal
  35. 2026-06-04publicationPublication — backfill
  36. 2026-04-28revisionRevision 1
  37. 2026-04-28absenceSearched ClinicalTrials.gov for "25C-NBOMe" — no results
  38. 2026-04-28genGeneration — pipeline-v5pipeline-v5
  39. 2026-04-28rungeneration run

The same entries, as forms: six forms.