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Psychedex

25B-NBOMe

4-bromo-2,5-dimethoxy-N-(2-methoxybenzyl)phenethylamine

1Provenance card

the boundary, as counts

Sources

2520 with DOI

1 strong · 13 moderate · 11 weak

Compilations

12026-04-25T21:18:14.682Z

pipeline-v5 · prompt hash not recorded — run predates 2026-09

Decisions

47last ruled 2026-06-04

0 awaiting a ruling

Issued documents

62026-10-19T20:29:05.438Z

notice · info card · emergency

Searches

192 with no results

queries and counts on the build

Claims checked

9776 supported

76 supported · 21 not

Correspondence

0received

consent field ships in Phase 4

Edges

303

derivations recorded for this entity

Complete over 25 sources, 1 compilation, and 47 decisions.Not here: the private journal (never).Working material — drafts, discards, unsupported claims — is listed below and readable on the working page.Cite: psychedex.org/substances/25b-nbome/archive

Timeline

what happened, newest first — claims, searches and artifacts stay inside Build

  1. 2026-10-19issueIssued emergency
  2. 2026-10-19issueIssued info_card
  3. 2026-10-19issueIssued notice
  4. 2026-09-07srcDesigner drugs: mechanism of action and adverse effects
  5. 2026-09-07srcNeurochemical and Behavioral Effects of a New Hallucinogenic Compound 25B-NBOMe in Rats.
  6. 2026-09-07srcNeurochemical pharmacology of psychoactive substituted N-benzylphenethylamines: High potency agonists at 5-HT2A receptors.
  7. 2026-09-07srcA fatal poisoning involving 25C-NBOMe.
  8. 2026-09-07srcDeath after 25C-NBOMe and 25H-NBOMe consumption.
  9. 2026-09-07srcMetabolic fate and detectability of 25B-NBOMe and 25C-NBOMe in human and rat urine by GC-MS, LC-MSn, and LC-HR-MS/MS approaches.
  10. 2026-09-07srcReceptor interaction profiles of novel N-2-methoxybenzyl (NBOMe) derivatives of 2,5-dimethoxy-substituted phenethylamines (2C drugs)
  11. 2026-09-07srcExtensive rigid analogue design maps the binding conformation of potent N-benzylphenethylamine 5-HT2A serotonin receptor agonist ligands.
  12. 2026-09-07srcSerotonin 2A receptor agonist binding in the human brain with [11C]Cimbi-36.
  13. 2026-09-07srcFatal Intoxications with 25B-NBOMe and 25I-NBOMe in Indiana During 2014.
  14. 2026-09-07srcAnalysis of 25I-NBOMe, 25B-NBOMe, 25C-NBOMe and Other Dimethoxyphenyl-N-[(2-Methoxyphenyl)Methyl]Ethanamine Derivatives on Blotter Paper.
  15. 2026-09-07src25B-NBOMe, a novel N-2-methoxybenzyl-phenethylamine (NBOMe) derivative, may induce rewarding and reinforcing effects via a dopaminergic mechanism: Evidence of abuse potential.
  16. 2026-09-07srcThe importance of small polar radiometabolites in molecular neuroimaging: A PET study with [11C]Cimbi-36 labeled in two positions.
  17. 2026-09-07srcLegal highs: staying on top of the flood of novel psychoactive substances
  18. 2026-09-07srcHuman biodistribution and radiation dosimetry of the 5-HT2A receptor agonist Cimbi-36 labeled with carbon-11 in two positions.
  19. 2026-09-07srcRadiosynthesis and Evaluation of 11C-CIMBI-5 as a 5-HT2A Receptor Agonist Radioligand for PET.
  20. 2026-09-07srcTwo cases of severe intoxication associated with analytically confirmed use of the novel psychoactive substances 25B-NBOMe and 25C-NBOMe.
  21. 2026-09-07srcCase series: toxicity from 25B-NBOMe--a cluster of N-bomb cases.
  22. 2026-09-07srcNBOMes-Highly Potent and Toxic Alternatives of LSD
  23. 2026-09-07src25b-NBOMe: A Case Report of Sudden Death and Insightful View of Google Trends Data.
  24. 2026-09-07src25B-NBOMe - Schedule I Placement (Temporary Scheduling, 25B/25I/25C-NBOMe)
  25. 2026-09-07srcNCT03289949: The Neurobiological Effect of 5-HT2AR Modulation
  26. 2026-09-07srcSchedules of Controlled Substances: Permanent Placement of Three Synthetic Phenethylamines Into Schedule I
  27. 2026-09-07srcCritical Review of 25B-NBOMe (Expert Committee on Drug Dependence)
  28. 2026-09-07srcNCT01778686: Evaluation of [11C]Cimbi-36 as an Agonist PET Radioligand for Imaging of 5-HT2A Receptors
  29. 2026-09-04issueIssued emergency
  30. 2026-09-04issueIssued info_card
  31. 2026-09-04issueIssued notice
  32. 2026-06-04proposal45 value proposals approved togetherone review action inferred from a shared reviewer and instant — the graph records one activity per proposal
  33. 2026-06-04publicationPublication — backfill
  34. 2026-04-25revisionRevision 1
  35. 2026-04-25absenceSearched PubMed for "25B-NBOMe toxicity overdose case report" — no results
  36. 2026-04-25absenceSearched ClinicalTrials.gov for "25B-NBOMe NBOMe Cimbi-36" — no results
  37. 2026-04-25genGeneration — pipeline-v5pipeline-v5
  38. 2026-04-25rungeneration run

The same entries, as forms: six forms.