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Psychedex

1Provenance card

the boundary, as counts

Sources

2112 with DOI

5 strong · 12 moderate · 4 weak

Compilations

12026-04-28T02:49:52.056Z

pipeline-v5 · prompt hash not recorded — run predates 2026-09

Decisions

28last ruled 2026-06-04

0 awaiting a ruling

Issued documents

42026-10-19T20:28:27.060Z

notice · info card · emergency

Searches

241 with no results

queries and counts on the build

Claims checked

7961 supported

61 supported · 18 not

Correspondence

0received

consent field ships in Phase 4

Edges

244

derivations recorded for this entity

Complete over 21 sources, 1 compilation, and 28 decisions.Not here: the private journal (never).Working material — drafts, discards, unsupported claims — is listed below and readable on the working page.Cite: psychedex.org/substances/1-3-butanediol/archive

Timeline

what happened, newest first — claims, searches and artifacts stay inside Build

  1. 2026-10-19issueIssued info_card
  2. 2026-10-02srcPharmacokinetic effects of a single dose nutritional ketone ester supplement on brain glucose and ketone metabolism in alcohol use disorder
  3. 2026-10-02srcKetone Supplementation Dampens Subjective and Objective Responses to Alcohol: Evidence From a Preclinical Rat Study and a Randomized, Cross-Over Trial in Healthy Volunteers
  4. 2026-10-02srcAcute and Intermittent Exogenous Ketosis to Support Recovery From Exercise and Adaptations to Exercise Training: A Narrative Review
  5. 2026-10-02srcThe Effect of 1,3-Butanediol on Cycling Time-Trial Performance
  6. 2026-10-02srcPhysiologic, Metabolic, and Toxicologic Profile of 1,3-Butanediol
  7. 2026-10-02srcKetone body β-hydroxybutyrate-mediated histone β-hydroxybutyrylation upregulates lipolysis and attenuates metabolic syndrome
  8. 2026-10-02srcPericonceptional 1,3-butanediol supplementation suppresses the superimposed preeclampsia-like phenotype in the Dahl salt-sensitive rat
  9. 2026-10-02srcCardiovascular and Metabolic Effects of Modulating Circulating Ketone Bodies With 1,3-Butanediol in Patients With Heart Failure With Reduced Ejection Fraction
  10. 2026-10-02srcKetone ester effects on metabolism and transcription
  11. 2026-10-02srcAn open-label, acute clinical trial in adults to assess ketone levels, gastrointestinal tolerability, and sleepiness following consumption of (R)-1,3-butanediol (Avela™)
  12. 2026-10-02srcTolerability and Safety of a Novel Ketogenic Ester, Bis-Hexanoyl (R)-1,3-Butanediol: A Randomized Controlled Trial in Healthy Adults
  13. 2026-10-02srcDisparate Hepatic Mitochondrial and Inflammatory Effects of Ketone Supplements
  14. 2026-10-02srcSuppression by 1,3-butanediol of the ethanol withdrawal syndrome in rats
  15. 2026-10-02srcNutritional and metabolic studies in humans with 1,3-butanediol
  16. 2026-10-02srcCharacterization of susceptibility to audiogenic seizures in ethanol-dependent rats after microinjection of GABA agonists
  17. 2026-10-02srcEffects of acute and chronic 1,3-butanediol treatment on central nervous system function: a comparison with ethanol
  18. 2026-10-02srcEffect of 1,3-butanediol on cerebral energy metabolism. Comparison with beta-hydroxybutyrate
  19. 2026-10-02src1,3-Butanediol - PsychonautWiki
  20. 2026-10-02src1,3-Butanediol - Wikipedia
  21. 2026-10-02srcR-1,3-Butanediol Production and Safety (Ketone-IQ Help Center)
  22. 2026-10-02src1,3-Butanediol Chemical Properties - ChemicalBook
  23. 2026-09-04issueIssued emergency
  24. 2026-09-04issueIssued info_card
  25. 2026-09-04issueIssued notice
  26. 2026-06-04proposal26 value proposals approved togetherone review action inferred from a shared reviewer and instant — the graph records one activity per proposal
  27. 2026-06-04publicationPublication — backfill
  28. 2026-04-28revisionRevision 1
  29. 2026-04-28absenceSearched PubMed for "1,3-butanediol pharmacology GABA GHB" — no results
  30. 2026-04-28genGeneration — pipeline-v5 · with 1 morepipeline-v5
  31. 2026-04-28rungeneration run

The same entries, as forms: six forms.