Zolpidem
1Provenance card
the boundary, as counts
Sources
4732 with DOI
18 strong · 21 moderate · 8 weak
Compilations
12026-04-28T02:26:56.300Z
pipeline-v5 · prompt hash not recorded — run predates 2026-09
Decisions
38last ruled 2026-06-04
0 awaiting a ruling
Issued documents
42026-10-19T20:34:27.206Z
notice · info card · emergency
Searches
250 with no results
queries and counts on the build
Claims checked
11980 supported
80 supported · 39 not
Correspondence
0received
consent field ships in Phase 4
Edges
361
derivations recorded for this entity
Complete over 47 sources, 1 compilation, and 38 decisions.Not here: the private journal (never).Working material — drafts, discards, unsupported claims — is listed below and readable on the working page.Cite: psychedex.org/substances/zolpidem/archive
Timeline
what happened, newest first — claims, searches and artifacts stay inside Build
- 2026-10-19issueIssued info_card
- 2026-09-24srcComparative bioavailability of two zolpidem hemitartrate formulations in healthy human Brazilian volunteers
- 2026-09-24srcAre Seniors Dependent on Benzodiazepines? A National Clinical Survey of Substance Use Disorder
- 2026-09-24srcThe effects of repeated zolpidem treatment on tolerance, withdrawal-like symptoms, and GABAA receptor mRNAs profile expression in mice: comparison with diazepam
- 2026-09-24srcSleep self-intoxication and sleep driving as rare zolpidem-induced complex behaviour
- 2026-09-24srcRelationship between plasma exposure of zolpidem and CYP2D6 genotype in healthy Korean subjects
- 2026-09-24srcBenzodiazepines and Z-Drugs: An Updated Review of Major Adverse Outcomes Reported on in Epidemiologic Research
- 2026-09-24srcProbing the molecular basis for affinity/potency- and efficacy-based subtype-selectivity exhibited by benzodiazepine-site modulators at GABAA receptors
- 2026-09-24srcReview of Safety and Efficacy of Sleep Medicines in Older Adults
- 2026-09-24srcSublingual zolpidem is more effective than oral zolpidem in initiating early onset of sleep
- 2026-09-24srcEfficacy and safety of insomnia pharmacotherapies: Convergent evidence from Bayesian network meta-regression and FAERS-based disproportionality analysis
- 2026-09-24srcExamination of Zolpidem effects on AhR- and PXR-dependent expression of drug-metabolizing cytochromes P450 in primary cultures of human hepatocytes
- 2026-09-24srcAcute effects of zolpidem extended-release on cognitive performance and sleep in healthy males after repeated nightly use
- 2026-09-24srcThe efficacy and safety of zolpidem and zopiclone to treat insomnia in Alzheimer's disease: a randomized, triple-blind, placebo-controlled trial
- 2026-09-24srcStructural and dynamic mechanisms of GABAA receptor modulators with opposing activities
- 2026-09-24srcAssessment of the Abuse Potential of the Orexin Receptor Antagonist, Suvorexant, Compared With Zolpidem in a Randomized Crossover Study
- 2026-09-24srcZolpidem and eszopiclone prime a1b2g2 GABAA receptors for longer duration of activity
- 2026-09-24srcDrug interaction between St John's wort and zolpidem in healthy subjects
- 2026-09-24srcThe European Insomnia Guideline: An update on the diagnosis and treatment of insomnia 2023
- 2026-09-24srcSedative hypnotics in older people with insomnia: meta-analysis of risks and benefits
- 2026-09-24srcEffects on sleep stages and microarchitecture of caffeine and its combination with zolpidem or trazodone in healthy volunteers
- 2026-09-24srcSex differences in pharmacokinetics predict adverse drug reactions in women
- 2026-09-24srcZolpidem for insomnia
- 2026-09-24srcComparative tolerability of newer agents for insomnia
- 2026-09-24srcZolpidem Versus Trazodone Initiation and the Risk of Fall-Related Fractures among Individuals Receiving Maintenance Hemodialysis
- 2026-09-24srcEffects of zolpidem on sleep parameters in patients with cirrhosis and sleep disturbances: A randomized, placebo-controlled trial
- 2026-09-24srcAssociation Between Z Drugs Use and Risk of Cognitive Impairment in Middle-Aged and Older Patients With Chronic Insomnia
- 2026-09-24srcCase report: Chronological symptom profile after cessation of overdose zolpidem in a patient with comorbid bipolar disorder
- 2026-09-24srcZolpidem withdrawal induced uncoupling of GABA(A) receptors in vitro associated with altered GABA(A) receptor subunit mRNA expression
- 2026-09-24srcComparison of the treatment effectiveness between lemborexant and zolpidem tartrate extended-release for insomnia disorder subtypes
- 2026-09-24srcSpontaneous Adverse Event Reports Associated with Zolpidem in the United States 2003-2012
- 2026-09-24srcClinical Practice Guideline for the Pharmacologic Treatment of Chronic Insomnia in Adults: An American Academy of Sleep Medicine Clinical Practice Guideline.
- 2026-09-24srcComparison of lemborexant with placebo and zolpidem tartrate extended release on sleep architecture in older adults
- 2026-09-24srcRegional differences in the inhibition of mouse in vivo [3H]Ro 15-1788 binding reflect selectivity for alpha1 versus alpha2 and alpha3 subunit-containing GABAA receptors
- 2026-09-24srcIndependence of sleep EEG responses to GABAergic hypnotics: biological implications
- 2026-09-24srcNew drugs for insomnia: comparative tolerability of zopiclone, zolpidem and zaleplon
- 2026-09-24srcNewer hypnotic drugs for the short-term management of insomnia: a systematic review and economic evaluation
- 2026-09-24srcZolpidem extended-release
- 2026-09-24srcHPLC quantification of zolpidem and prothipendyl in a voluntary intoxication
- 2026-09-24srcLow-dose sublingual zolpidem tartrate is associated with dose-related improvement in sleep onset and duration in insomnia characterized by middle-of-the-night awakenings
- 2026-09-24srcZolpidem intoxication mimicking narcotic overdose: response to flumazenil
- 2026-09-24srcZolpidem dependence and withdrawal seizure--report of two cases
- 2026-09-24srcSilencing the brain may be better than stimulating it. The GABA effect
- 2026-09-24srcZolpidem dependence, abuse and withdrawal: A case report
- 2026-09-24srcZolpidem and rebound insomnia--a double-blind, controlled polysomnographic study in chronic insomniac patients
- 2026-09-24srcClinical pharmacokinetics and pharmacodynamics of zolpidem. Therapeutic implications
- 2026-09-24srcZolpidem - StatPearls
- 2026-09-24srcFDA requires lower recommended doses for certain drugs containing zolpidem (Ambien, Ambien CR, Edluar, Zolpimist)
- 2026-09-04issueIssued emergency
- 2026-09-04issueIssued info_card
- 2026-09-04issueIssued notice
- 2026-06-04proposal36 value proposals approved togetherone review action inferred from a shared reviewer and instant — the graph records one activity per proposal
- 2026-06-04publicationPublication — backfill
- 2026-04-28revisionRevision 1
- 2026-04-28genGeneration — pipeline-v5 · with 2 morepipeline-v5
- 2026-04-28rungeneration run
The same entries, as forms: six forms.