Skip to main content
Psychedex
Facts label

Tetrahydrocannabihexol Facts

Cannabinoid; Cannabinoid; Cannabinoid CB1 receptor full agonist

Dose and duration

No dose or duration recorded for any route.

Body and dependence

Acute toxicity
Moderate
Chronic toxicity
Low
Physical dependence
Low
Psychological dependence
Moderate
Withdrawal
Moderate
Compulsive redosing
Low

Tolerance

Builds
Moderate
Fully resets after
21 days
Carries over to
Δ9-THC; Δ8-THC; THCP; THCB; HHC; Synthetic cannabinoids

Effectslikely at a common dose

Perception
none likely · 18 possible, including Spatial disorientation, Vestibular distortion, Visual haze / noise
Body
Body high; Dry mouth; +20 possible, including Abnormal heartbeat, Motor control impairment, Dizziness
Thinking
Cognitive impairment; Memory suppression; +32 possible, including Decision impairment, Information processing suppression, Analysis suppression
Feeling
none likely · 10 possible, including Anxiety, Emotional lability, Paranoia
Self
none likely · 14 possible, including Communication suppression, Depersonalization, Derealization
Time
Time alteration; +2 possible, including Temporal disorientation
Awareness
none likely · 2 possible

Who shouldn't take it

Absolute
Psychotic disorders; Pregnancy and breastfeeding
Relative
Cardiovascular disease; Cannabis use disorder; Hepatic impairment; Adolescence; Concurrent CNS depressant use

Combinations60 recorded

Dangerous (27)
Benzodiazepines, Barbiturates; GHB, Baclofen; GHB, GBL; Opioids; Alpha-2 adrenergic receptor antagonist; Atypical antipsychotics; Benzodiazepines; Caffeine; Cannabis; Cannabis, THC; Clonidine, Guanfacine; Ephedrine, Pseudoephedrine; Gabapentin, Pregabalin; Ibogaine; Ketamine, DXM, PCP; Lithium; Local anesthetics; MAOIs; MDMA, MDA; NDRIs (Wellbutrin); Salvia, Ibogaine; SNRIs; SSRIs; THC; and 3 more, see full page
Caution (21)
See full page: psychedex.org/substances/tetrahydrocannabihexol
Not graded (12)
Not listed never means safe.

Seek help immediately if

Natural cannabis rarely causes a medical emergency — "greening out" is: pale/sweaty skin, dizziness, nausea or vomiting, anxiety or panic, rapid heartbeat, feeling faint — and usually passes with rest.

Seek emergency help for these — far more likely with synthetic cannabinoids ("spice" / K2):

  • Seizures
  • Severe chest pain; very fast or irregular heartbeat
  • Unresponsiveness or extreme drowsiness
  • Severe agitation, aggression, or psychosis
  • Repeated vomiting; difficulty breathing

What to do

  1. Sit or lie them down somewhere calm, cool, and quiet
  2. Reassure them — cannabis panic and "greening out" pass with time
  3. Offer sips of water; a little sugar can help if they feel faint
  4. Recovery position if nauseated, drowsy, or vomiting
  5. Stay with them and monitor
  6. For seizures, chest pain, unresponsiveness, or severe agitation, call emergency services

Natural cannabis "greening out" resolves with rest, calm, and time, with no lasting harm. Synthetic cannabinoids are unpredictable and can cause seizures, cardiac events, kidney injury, and severe agitation that needs emergency care.

988 Suicide & Crisis LifelineFireside Project: 62-FIRESIDE

psychedex.org/substances/tetrahydrocannabihexol · Version r1 · Not medical adviceValues as of
On the printout