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1Provenance card

the boundary, as counts

Sources

4222 with DOI

7 strong · 29 moderate · 6 weak

Compilations

12026-05-15T20:43:14.016Z

pipeline-v5 · prompt hash not recorded — run predates 2026-09

Decisions

29last ruled 2026-06-04

0 awaiting a ruling

Issued documents

42026-10-19T20:34:04.573Z

notice · info card · emergency

Searches

191 with no results

queries and counts on the build

Claims checked

7555 supported

55 supported · 20 not

Correspondence

0received

consent field ships in Phase 4

Edges

253

derivations recorded for this entity

Complete over 42 sources, 1 compilation, and 29 decisions.Not here: the private journal (never).Working material — drafts, discards, unsupported claims — is listed below and readable on the working page.Cite: psychedex.org/substances/sufentanil/archive

Timeline

what happened, newest first — claims, searches and artifacts stay inside Build

  1. 2026-10-19issueIssued info_card
  2. 2026-09-07srcPopulation pharmacokinetic modeling of sufentanil in adult Korean patients undergoing cardiopulmonary bypass surgery
  3. 2026-09-07srcFentanyls continue to replace heroin in the drug arena: the cases of ocfentanil and carfentanil
  4. 2026-09-07srcCircumstantial and toxicological features of deaths from self-administered intravenous anesthetic/narcotic agents
  5. 2026-09-07srcAnalgesic Efficacy and Adverse Effects of Epidural Ropivacaine Combined with Equipotent Alfentanil or Sufentanil for Labor Analgesia
  6. 2026-09-07srcPharmacokinetics of Opioid Infusions in the Adult Intensive Care Unit Setting—A Systematic Review
  7. 2026-09-07srcPharmacokinetics of Sufentanil After Epidural Administration During the Course of Extensive Abdominal Surgery
  8. 2026-09-07srcMeperidine, remifentanil and tramadol but not sufentanil interact with alpha(2)-adrenoceptors in alpha(2A)-, alpha(2B)- and alpha(2C)-adrenoceptor knock out mice brain
  9. 2026-09-07srcThe fentanyl story
  10. 2026-09-07srcSupersensitivity to mu-opioid receptor-mediated inhibition of the adenylyl cyclase pathway involves pertussis toxin-resistant Galpha protein subunits
  11. 2026-09-07srcUniform assessment and ranking of opioid mu receptor binding constants for selected opioid drugs
  12. 2026-09-07srcEffects of OPRM1 and ABCB1 gene polymorphisms on the analgesic effect and dose of sufentanil after thoracoscopic-assisted radical resection of lung cancer
  13. 2026-09-07srcIntranasal Naloxone Reversal of Opioid-induced Respiratory Depression in Opioid-naive Individuals and Self-reported Daily Opioid Users
  14. 2026-09-07srcCarfentanil is a β-arrestin-biased agonist at the µ opioid receptor
  15. 2026-09-07srcChronic opioid treatment augments caveolin-1 scaffolding: relevance to stimulatory μ-opioid receptor adenylyl cyclase signaling
  16. 2026-09-07srcIntranasal sufentanil/ketamine analgesia in children
  17. 2026-09-07srcPharmacokinetics and Pharmacodynamics of Analgesic and Anesthetic Drugs in Patients During Cardiac Surgery With Cardiopulmonary Bypass
  18. 2026-09-07srcSafety and Efficacy of Sufentanil and Fentanyl Analgesia in Patients with Traumatic Brain Injury: A Retrospective Study
  19. 2026-09-07srcRole of kinin B2 receptors in opioid-induced hyperalgesia in inflammatory pain in mice
  20. 2026-09-07srcEffects of Intrathecal Sufentanil at Different Doses on Postoperative Pain Relief and Opioid Consumption in Elderly Patients Undergoing Lower Limb Orthopedic Surgery: A Randomized Controlled Trial
  21. 2026-09-07srcPooled Phase III safety analysis of sufentanil sublingual tablets for short-term treatment of moderate-to-severe acute pain
  22. 2026-09-07srcStudy on Stability of Remifentanil, Sufentanil, and Their Metabolites in Human Whole Blood and Urine
  23. 2026-09-07srcFentanyl Family at the Mu-Opioid Receptor: Uniform Assessment of Binding and Computational Analysis
  24. 2026-09-07srcSufentanil, a very potent and extremely safe intravenous morphine-like compound in mice, rats and dogs
  25. 2026-09-07srcRelative analgesic potency of fentanyl and sufentanil during intermediate-term infusions in patients after long-term opioid treatment for chronic pain
  26. 2026-09-07srcReceptor endocytosis counteracts the development of opioid tolerance
  27. 2026-09-07srcAnalgesia in PACU: intravenous opioids
  28. 2026-09-07srcTolerance to the respiratory actions of opiates: withdrawal tolerance and asymmetrical cross-tolerance
  29. 2026-09-07srcMagnitude of opioid dependence after continuous intrathecal infusion of mu- and delta-selective opioids in the rat
  30. 2026-09-07srcSublingual sufentanil, a new opportunity for the improvement of postoperative pain management in Italy
  31. 2026-09-07srcSufentanil and midazolam dosing and pharmacogenetic factors in pediatric analgosedation and withdrawal syndrome
  32. 2026-09-07srcComparison of morphine, meperidine, fentanyl, and sufentanil in balanced anesthesia: a double-blind study
  33. 2026-09-07srcEpidural analgesia with sufentanil in relation to OPRM1 and ABCB1 polymorphisms
  34. 2026-09-07srcThe pharmacokinetics of sufentanil in surgical patients
  35. 2026-09-07srcDisappearance of morphine-induced hyperalgesia after discontinuing or substituting morphine with other opioid agonists
  36. 2026-09-07srcIdentification of human liver cytochrome P-450 3A4 as the enzyme responsible for fentanyl and sufentanil N-dealkylation
  37. 2026-09-07srcCo-induction of anaesthesia: day-case surgery
  38. 2026-09-07srcClinical pharmacokinetics of alfentanil, fentanyl and sufentanil. An update
  39. 2026-09-07srcDURECT Corporation Says Endo Pharmaceuticals Returns Rights to Chronogesic
  40. 2026-09-07srcSufentanil Citrate Injection FDA label via DailyMed (NDA 019050)
  41. 2026-09-07srcPubChem Compound Record: Sufentanil (CID 41693)
  42. 2026-09-07srcMisuse of Drugs Act 1971 (Modification) Order 1983 - UK legislation
  43. 2026-09-07srcDsuvia (sufentanil) FDA Approval History
  44. 2026-09-04issueIssued emergency
  45. 2026-09-04issueIssued info_card
  46. 2026-09-04issueIssued notice
  47. 2026-06-04proposal27 value proposals approved togetherone review action inferred from a shared reviewer and instant — the graph records one activity per proposal
  48. 2026-06-04publicationPublication — backfill
  49. 2026-05-15revisionRevision 1
  50. 2026-05-15absenceSearched PubMed for "sufentanil synthesis history discovery Paul Janssen" — no results
  51. 2026-05-15genGeneration — pipeline-v5 · with 2 morepipeline-v5
  52. 2026-05-15rungeneration run

The same entries, as forms: six forms.