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Quetiapine Facts

Antipsychotic; Sedative; Dibenzothiazepine; Dopamine D2 receptor antagonist

Dose and durationby route · individual sensitivity varies

Oral(mg)
Threshold< 10 mgLight25 – 50 mgCommon50 – 150 mgStrong150 – 300 mgHeavy300+ mg

Starts in 20 – 40 minLasts 8 – 24 hoursAfter-effects 24 – 48 hours

Body and dependence

Acute toxicity
Low
Chronic toxicity
Low
Physical dependence
Not assessed
Psychological dependence
Not assessed
Withdrawal
Not assessed
Compulsive redosing
Not assessed

Tolerance

Builds
Within a week of continuous use
Fully resets after
10.5 days

Effectslikely at a common dose

Body
none likely · 8 possible, including Dizziness, Dehydration sensation, Motor control impairment
Thinking
none likely · 6 possible, including Language suppression, Thought disorganization, Analysis suppression

Who shouldn't take it

None recorded. Not listed never means safe to take.

Combinations60 recorded

Dangerous (32)
Anticholinergics; Antihistamines; Benzodiazepines, Barbiturates; Buprenorphine, Kratom; DXM; GHB, GBL; Lithium; MAOIs; MDMA, MDA; Opioids; Amphetamines; Antipsychotics; Atypical antipsychotics; Benzodiazepines; Buspirone; Clonidine, Guanfacine; Gabapentin, Pregabalin; GHB, Baclofen; Ibogaine; Local anesthetics; MDMA, Amphetamines; Naltrexone; NDRIs (Wellbutrin); NRIs; and 8 more, see full page
Caution (23)
See full page: psychedex.org/substances/quetiapine
Not graded (5)
Not listed never means safe.

Seek help immediately if

No emergency profile is recorded for this substance. Not recorded never means no risk.

988 Suicide & Crisis LifelineFireside Project: 62-FIRESIDE

psychedex.org/substances/quetiapine · Version r1 · Not medical adviceValues as of
On the printout