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Entity
Quetiapine
PSX-0319
Open Beta
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Common namesQuetiapine, Seroquel
Substitutive name2-[2-(4-dibenzo[b,f][1,4]thiazepin-11-yl-1-piperazinyl)ethoxy]ethanol
PsychoactiveAntipsychotic
+1 more
SedativeChemicalDibenzothiazepine
Threshold
< 10 mg
Light
25 – 50 mg
Common
50 – 150 mg
Strong
150 – 300 mg
Heavy
300+ mg
Bioavailability:100%
Onset
20 – 40 min
Peak
1.5 – 6 hours
Offset
6 – 7 hours
After effects
24 – 48 hours
Total:8 – 24 hours
minlowmodhigh
Acute
Chronic
Physical
Psych.
Withdrawalnot assessed
Buildupwithin a week of continuous use
Full reset10.5 days
caution23
Dosage varies by body weight, tolerance & metabolism · Not medical advice · Terms
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Effects (24)
Perception
Dreaming enhancementBody
SedationBodily heavinessDizzinessDehydration sensationMotor control impairmentHeadacheSexual arousal suppressionAbnormal heartbeatAppetite enhancementIncreased urinationNausea suppressionThinking
Creativity suppressionLanguage suppressionFocus suppressionMotivation suppressionAmnesiaThought disorganizationThought decelerationAnalysis suppressionSelf
DisinhibitionDependence
moderately physically and psychologically addictive
experience reports
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First-person accounts of subjective effects, timing, and outcomes — submitted for harm reduction.
Last updated Mar 17, 2026Report an issue