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Prolintane Facts

Stimulant; Substituted pyrrolidine; Norepinephrine-dopamine reuptake inhibitor

Dose and durationby route · individual sensitivity varies

Oral(mg)
Threshold< 5 mgLight15 – 25 mgCommon25 – 45 mgStrong45 – 60 mgHeavy60+ mg

Starts in 20 – 60 minLasts 4 – 6 hoursAfter-effects 2 – 6 hours

Body and dependence

Acute toxicity
Moderate
Chronic toxicity
Moderate
Physical dependence
Low
Psychological dependence
Moderate
Withdrawal
Mild
Compulsive redosing
Moderate

Tolerance

Builds
Moderate
Fully resets after
14 days
Carries over to
cocaine; methylphenidate; pyrovalerone

Effectslikely at a common dose

Body
Appetite suppression; Wakefulness; Stimulation; Pupil dilation; +13 possible, including Muscle tension, Insomnia, Vasoconstriction
Thinking
Thought acceleration; +10 possible, including Compulsive redosing urge
Feeling
none likely · 6 possible, including Anxiety, Anhedonia, Depression
Self
none likely · 6 possible, including Ego inflation, Craving

Who shouldn't take it

Absolute
Long QT syndrome; Concurrent QT-prolonging medication; Pregnancy
Relative
Cardiovascular disease; Hypertension; Seizure disorders; Psychotic disorders; Hyperthyroidism; Concurrent serotonergic medication

Combinations61 recorded

Lethal (1)
Tramadol
Dangerous (29)
Amphetamines; Ephedrine, Pseudoephedrine; Local anesthetics; MAOIs; MDMA, Amphetamines; NRIs; Stimulants; Alpha-2 adrenergic receptor antagonist; Anticholinergics; Antipsychotics; Caffeine; Clonidine, Guanfacine; Dopamine agonists; GHB, Baclofen; GHB, GBL; Ibogaine; Ketamine, DXM, PCP; Lithium; MDMA, MDA; NSAIDs; Opioids; Poppers (Alkyl nitrites); Poppers, Nitrates; Psychedelics; and 5 more, see full page
Caution (27)
See full page: psychedex.org/substances/prolintane
Not graded (4)
Not listed never means safe.

Seek help immediately if

  • Chest pain; racing, pounding, or irregular heartbeat
  • Very high body temperature; heavy sweating; hot, flushed skin
  • Severe agitation, paranoia, panic, or confusion
  • Severe headache; muscle rigidity or twitching
  • Seizures
  • Signs of stroke — face drooping, one-sided weakness, slurred speech
  • Difficulty breathing; collapse or unconsciousness

What to do

  1. Call emergency services for chest pain, overheating, seizure, or unresponsiveness
  2. Move them to a cool, quiet place and reduce stimulation
  3. Cool the body — remove excess clothing, apply cool damp cloths, fan them
  4. Keep them calm; reassure — panic worsens the cardiovascular strain
  5. If seizing, protect from injury (don't restrain); recovery position afterward
  6. Monitor breathing and be ready to give rescue breaths / CPR

Most stimulant overdoses settle with cooling, a calm environment, and time. The medical danger is hyperthermia, cardiac events (arrhythmia, heart attack, stroke), and seizures — get help immediately if any appear.

988 Suicide & Crisis LifelineFireside Project: 62-FIRESIDE

psychedex.org/substances/prolintane · Version r1 · Not medical adviceValues as of
On the printout