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1Provenance card

the boundary, as counts

Sources

3720 with DOI

12 strong · 17 moderate · 8 weak

Compilations

12026-05-12T05:36:57.961Z

pipeline-v5 · prompt hash not recorded — run predates 2026-09

Decisions

33last ruled 2026-06-04

0 awaiting a ruling

Issued documents

42026-10-19T20:33:37.650Z

notice · info card · emergency

Searches

250 with no results

queries and counts on the build

Claims checked

6541 supported

41 supported · 24 not

Correspondence

0received

consent field ships in Phase 4

Edges

238

derivations recorded for this entity

Complete over 37 sources, 1 compilation, and 33 decisions.Not here: the private journal (never).Working material — drafts, discards, unsupported claims — is listed below and readable on the working page.Cite: psychedex.org/substances/phentermine/archive

Timeline

what happened, newest first — claims, searches and artifacts stay inside Build

  1. 2026-10-19issueIssued info_card
  2. 2026-09-07srcChanges in cardiovascular risk associated with phentermine and topiramate extended-release in participants with comorbidities and a body mass index ≥27 kg/m²
  3. 2026-09-07srcThe long-term effectiveness of the anti-obesity medication phentermine (LEAP) trial: Rationale, design, and baseline characteristics
  4. 2026-09-07srcAbuse liability assessment of atomoxetine in a drug-abusing population
  5. 2026-09-07srcPhentermine involvement in fatal drug overdoses in Tennessee, 2019-2022
  6. 2026-09-07srcEffects of low-dose, controlled-release, phentermine plus topiramate combination on weight and associated comorbidities in overweight and obese adults (CONQUER): a randomised, placebo-controlled, phase 3 trial
  7. 2026-09-07srcAddiction potential of phentermine prescribed during long-term treatment of obesity
  8. 2026-09-07srcControlled-release phentermine/topiramate in severely obese adults: a randomized controlled trial (EQUIP)
  9. 2026-09-07srcThe cardiovascular safety of antiobesity drugs - analysis of signals in the FDA Adverse Event Report System Database
  10. 2026-09-07srcAnti-obesity medication for weight loss in early nonresponders to behavioral treatment: a randomized controlled trial
  11. 2026-09-07srcA systematic review and meta-analysis of the efficacy and safety of pharmacological treatments for obesity in adults
  12. 2026-09-07srcPhentermine/Topiramate for the Treatment of Adolescent Obesity
  13. 2026-09-07srcReal-World Use of Phentermine and Topiramate for Adolescent Obesity: Retrospective Effectiveness and Safety Analysis
  14. 2026-09-07srcAntidepressant and antiobesity drug-induced serotonin syndrome complicated by multiple organ injury: A case report
  15. 2026-09-07srcA study of abrupt phentermine cessation in patients in a weight management program
  16. 2026-09-07srcD1 and D2 antagonists reverse the effects of appetite suppressants on weight loss, food intake, locomotion, and rebalance spiking inhibition in the rat NAc shell
  17. 2026-09-07srcWeight-loss therapy in type 2 diabetes: effects of phentermine and topiramate extended release
  18. 2026-09-07srcCardiometabolic Disease Staging Predicts Effectiveness of Weight-Loss Therapy to Prevent Type 2 Diabetes: Pooled Results From Phase III Clinical Trials Assessing Phentermine/Topiramate Extended Release
  19. 2026-09-07srcPulmonary hypertension associated with use of phentermine
  20. 2026-09-07srcTwo-year sustained weight loss and metabolic benefits with controlled-release phentermine/topiramate in obese and overweight adults (SEQUEL): a randomized, placebo-controlled, phase 3 extension study
  21. 2026-09-07srcAssessment of the Risk Evaluation and Mitigation Strategy (REMS) for Phentermine-Topiramate to Prevent Exposure During Pregnancy
  22. 2026-09-07srcAmphetamine-type central nervous system stimulants release norepinephrine more potently than they release dopamine and serotonin
  23. 2026-09-07srcPharmacologic options for the treatment of obesity
  24. 2026-09-07srcAutopsy findings of heart and lungs in a patient with primary pulmonary hypertension associated with use of fenfluramine and phentermine
  25. 2026-09-07srcNoradrenergic and dopaminergic effects of (+)-amphetamine-like stimulants in the baboon Papio anubis
  26. 2026-09-07srcLong-term weight control study. I (weeks 0 to 34). The enhancement of behavior modification, caloric restriction, and exercise by fenfluramine plus phentermine versus placebo
  27. 2026-09-07srcLong-term weight control study: conclusions
  28. 2026-09-07srcCentral nervous system biogenic amine targets for control of appetite and energy expenditure
  29. 2026-09-07srcClinical experience using appetite suppressants and SSRIs
  30. 2026-09-07srcPhentermine -- a 'weighty' or a dangerous substance?
  31. 2026-09-07srcPhentermine - PubChem Compound CID 4771
  32. 2026-09-07srcEffects of phentermine and cocaine on fenfluramine-induced depletion of serotonin in mouse brain
  33. 2026-09-07srcValvular heart disease associated with fenfluramine-phentermine
  34. 2026-09-07srcEffects of phentermine on striatal dopamine and serotonin release in conscious rats: in vivo microdialysis study
  35. 2026-09-07srcPhentermine Hydrochloride Tablets (Adipex-P) Prescribing Information
  36. 2026-09-07srcPhentermine free base - CAS 122-09-8 chemical identity
  37. 2026-09-07srcPhentermine (PIM 415) - INCHEM International Programme on Chemical Safety
  38. 2026-09-07srcDEA Orange Book: Alphabetical Listing of Controlled Substances
  39. 2026-09-04issueIssued emergency
  40. 2026-09-04issueIssued info_card
  41. 2026-09-04issueIssued notice
  42. 2026-06-04proposal31 value proposals approved togetherone review action inferred from a shared reviewer and instant — the graph records one activity per proposal
  43. 2026-06-04publicationPublication — backfill
  44. 2026-05-12revisionRevision 1
  45. 2026-05-12genGeneration — pipeline-v5 · with 2 morepipeline-v5
  46. 2026-05-12rungeneration run

The same entries, as forms: six forms.