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1Provenance card

the boundary, as counts

Sources

4525 with DOI

16 strong · 16 moderate · 13 weak

Compilations

12026-05-09T20:10:44.449Z

pipeline-v5 · prompt hash not recorded — run predates 2026-09

Decisions

32last ruled 2026-06-04

0 awaiting a ruling

Issued documents

42026-10-19T20:33:28.219Z

notice · info card · emergency

Searches

210 with no results

queries and counts on the build

Claims checked

10274 supported

74 supported · 28 not

Correspondence

0received

consent field ships in Phase 4

Edges

315

derivations recorded for this entity

Complete over 45 sources, 1 compilation, and 32 decisions.Not here: the private journal (never).Working material — drafts, discards, unsupported claims — is listed below and readable on the working page.Cite: psychedex.org/substances/oxymorphone/archive

Timeline

what happened, newest first — claims, searches and artifacts stay inside Build

  1. 2026-10-19issueIssued info_card
  2. 2026-09-07srcClinical Pharmacology, Toxicity, and Abuse Potential of Opioids
  3. 2026-09-07srcOxymorphone and Oxycodone Pharmacy Purchases in US Counties: Prelude to the Largest Rural HIV Outbreak in US History
  4. 2026-09-07srcBilateral exudative retinal detachments due to thrombotic microangiopathy associated with intravenous abuse of Opana ER
  5. 2026-09-07srcMultiple injections per injection episode: High-risk injection practice among people who injected pills during the 2015 HIV outbreak in Indiana
  6. 2026-09-07srcA large HCV transmission network enabled a fast-growing HIV outbreak in rural Indiana, 2015
  7. 2026-09-07srcExploring the impact of CYP2D6 and UGT2B7 gene-drug interactions, and CYP-mediated DDI on oxycodone and oxymorphone pharmacokinetics using physiologically-based pharmacokinetic modeling
  8. 2026-09-07srcThe effects of ethanol on the bioavailability of oxymorphone extended-release tablets and oxymorphone crush-resistant extended-release tablets
  9. 2026-09-07srcA systematic review of oxymorphone in the management of chronic pain
  10. 2026-09-07srcUniform assessment and ranking of opioid mu receptor binding constants for selected opioid drugs
  11. 2026-09-07srcOpioid metabolism
  12. 2026-09-07srcThrombotic microangiopathy and acute kidney injury associated with intravenous abuse of an oral extended-release formulation of oxymorphone hydrochloride: kidney biopsy findings and report of 3 cases
  13. 2026-09-07srcHIV Infection Linked to Injection Use of Oxymorphone in Indiana, 2014-2015
  14. 2026-09-07srcOpioids for chronic low back pain management: a Bayesian network meta-analysis
  15. 2026-09-07srcCase Report of Methylone, Oxymorphone and Ethanol in a Fatality Case with Tissue Distribution
  16. 2026-09-07srcRelative Abuse of Crush-Resistant Prescription Opioid Tablets via Alternative Oral Modes of Administration
  17. 2026-09-07srcPharmacodynamic effects of oral oxymorphone: abuse liability, analgesic profile and direct physiologic effects in humans
  18. 2026-09-07srcA case of rhabdomyolysis associated with severe opioid withdrawal
  19. 2026-09-07srcAcute kidney injury is common with intravenous abuse of extended-release oral oxymorphone and delayed renal recovery rates are associated with increased KDIGO staging
  20. 2026-09-07srcChanges in prevalence of prescription opioid abuse after introduction of an abuse-deterrent opioid formulation
  21. 2026-09-07srcOpana ER (Oxymorphone)-Induced Thrombotic Microangiopathy: An Atypical Presentation in a Patient With Hepatitis C
  22. 2026-09-07srcThe efficacy and safety of oral immediate-release oxymorphone for postsurgical pain
  23. 2026-09-07srcSide Effect Rates of Opioids in Equianalgesic Doses via Intravenous Patient-Controlled Analgesia: A Systematic Review and Network Meta-analysis
  24. 2026-09-07srcPharmacological investigations of N-substituent variation in morphine and oxymorphone: opioid receptor binding, signaling and antinociceptive activity
  25. 2026-09-07srcComprehensive molecular pharmacology screening reveals potential new receptor interactions for clinically relevant opioids
  26. 2026-09-07srcConcomitant Filled Prescriptions of Oxymorphone or Oxycodone with CYP3A Inhibitors and Inducers
  27. 2026-09-07srcClinical pharmacology of opioids for pain
  28. 2026-09-07srcOxymorphone extended release does not affect CYP2C9 or CYP3A4 metabolic pathways
  29. 2026-09-07srcSingle- and multiple-dose pharmacokinetic and dose-proportionality study of oxymorphone immediate-release tablets
  30. 2026-09-07srcOxymorphone extended-release tablets relieve moderate to severe pain and improve physical function in osteoarthritis: results of a randomized, double-blind, placebo- and active-controlled phase III trial
  31. 2026-09-07srcA 2-week, multicenter, randomized, double-blind, placebo-controlled, dose-ranging, phase III trial comparing the efficacy of oxymorphone extended release and placebo in adults with pain associated with osteoarthritis of the hip or knee
  32. 2026-09-07srcEfficacy and tolerability of oxymorphone immediate release for acute postoperative pain after abdominal surgery: a randomized, double-blind, active- and placebo-controlled, parallel-group trial
  33. 2026-09-07srcReview of oral oxymorphone in the management of pain
  34. 2026-09-07srcAn overdose death involving the insufflation of extended-release oxymorphone tablets.
  35. 2026-09-07srcPositive and negative subjective effects of extended-release oxymorphone versus controlled-release oxycodone in recreational opioid users
  36. 2026-09-07srcCommunity Outbreak of HIV Infection Linked to Injection Drug Use of Oxymorphone—Indiana, 2015
  37. 2026-09-07srcOpioid associated intravenous and cutaneous microvascular drug abuse masquerading as Degos disease with multiorgan involvement
  38. 2026-09-07srcOxymorphone Induced Thrombotic Microangiopathy Mimicking Atypical Haemolytic Uremic Syndrome
  39. 2026-09-07srcCombination of delta9-tetrahydrocannabinol with oxymorphone or pentobarbital: Effects on ventilatory control and cardiovascular dynamics
  40. 2026-09-07srcOxymorphone — PubChem Compound Summary
  41. 2026-09-07srcGenetically deficient CYP2D6 metabolism provides protection against oral opiate dependence
  42. 2026-09-07srcOxymorphone (Opana) prescribing information — FDA label
  43. 2026-09-07srcOxymorphone (marketed as Opana ER) Information
  44. 2026-09-07srcFederal Register — Withdrawal of Approval of NDA for OPANA ER
  45. 2026-09-07srcOxymorphone pharmacokinetics: bioavailability, half-life, protein binding
  46. 2026-09-07srcOxymorphone — DEA Diversion Control Division Drug Chemical Information
  47. 2026-09-04issueIssued emergency
  48. 2026-09-04issueIssued info_card
  49. 2026-09-04issueIssued notice
  50. 2026-06-04proposal30 value proposals approved togetherone review action inferred from a shared reviewer and instant — the graph records one activity per proposal
  51. 2026-06-04publicationPublication — backfill
  52. 2026-05-09revisionRevision 1
  53. 2026-05-09genGeneration — pipeline-v5 · with 2 morepipeline-v5
  54. 2026-05-09rungeneration run

The same entries, as forms: six forms.