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1Provenance card

the boundary, as counts

Sources

2116 with DOI

2 strong · 10 moderate · 9 weak

Compilations

12026-04-26T21:50:45.801Z

pipeline-v5 · prompt hash not recorded — run predates 2026-09

Decisions

45last ruled 2026-06-04

0 awaiting a ruling

Issued documents

42026-10-19T20:33:24.319Z

notice · info card · emergency

Searches

234 with no results

queries and counts on the build

Claims checked

8870 supported

70 supported · 18 not

Correspondence

0received

consent field ships in Phase 4

Edges

278

derivations recorded for this entity

Complete over 21 sources, 1 compilation, and 45 decisions.Not here: the private journal (never).Working material — drafts, discards, unsupported claims — is listed below and readable on the working page.Cite: psychedex.org/substances/o-pce/archive

Timeline

what happened, newest first — claims, searches and artifacts stay inside Build

  1. 2026-10-19issueIssued info_card
  2. 2026-09-24srcMetabolic profiling of deschloro-N-ethyl-ketamine and identification of new target metabolites in urine and hair using human liver microsomes and high-resolution accurate mass spectrometry
  3. 2026-09-24src1,2-Diarylethylamine- and Ketamine-Based New Psychoactive Substances
  4. 2026-09-24srcKetamine-derived designer drug methoxetamine: metabolism including isoenzyme kinetics and toxicological detectability using GC-MS and LC-(HR-)MSn
  5. 2026-09-24srcKetamine: A Review of Clinical Pharmacokinetics and Pharmacodynamics in Anesthesia and Pain Therapy
  6. 2026-09-24srcCluster of acute poisonings associated with an emerging ketamine analogue, 2-oxo-PCE
  7. 2026-09-24srcFatal intoxication related to two new arylcyclohexylamine derivatives (2F-DCK and 3-MeO-PCE)
  8. 2026-09-24srcA combined toxicokinetic and metabolic approach to investigate deschloro-N-ethylketamine exposure in a multidrug user
  9. 2026-09-24srcThe clinical toxicology of ketamine
  10. 2026-09-24srcThe Emergence of Deschloro-N-ethyl-ketamine, a Ketamine Analog, in Drug Seizures and Drug Driving Cases in Hong Kong
  11. 2026-09-24srcIn vitro and in vivo metabolic study of three new psychoactive β-keto-arylcyclohexylamines
  12. 2026-09-24srcA Fatal Case Involving N-Ethyldeschloroketamine (2-Oxo-PCE) and Venlafaxine
  13. 2026-09-24srcPharmacogenetic and drug interaction aspects on ketamine safety in its use as antidepressant - implications for precision dosing
  14. 2026-09-24src2-oxo-PCE: ketamine analogue on the streets
  15. 2026-09-24srcThe ketamine analogue methoxetamine and 3- and 4-methoxy analogues of phencyclidine are high affinity and selective ligands for the glutamate NMDA receptor
  16. 2026-09-24srcDetermination of Arylcyclohexylamines in Biological Specimens: Sensors and Sample Pre-Treatment Approaches
  17. 2026-09-24srcKetamine for Depression, 5: Potential Pharmacokinetic and Pharmacodynamic Drug Interactions
  18. 2026-09-24srcTolerance to the cataleptic effect of the N-methyl-D-aspartate (NMDA) receptor antagonists in pigeons: cross-tolerance between PCP-like compounds and competitive NMDA antagonists
  19. 2026-09-24srcInteraction of the chiral forms of ketamine with opioid, phencyclidine, sigma and muscarinic receptors
  20. 2026-09-24src2-Oxo-PCE (Wikipedia / Grokipedia mirror)
  21. 2026-09-24srcDeschloro-N-ethyl Ketamine (O-PCE) Monograph
  22. 2026-09-24srcDeschloro-N-ethyl-ketamine Substance Entry
  23. 2026-09-04issueIssued emergency
  24. 2026-09-04issueIssued info_card
  25. 2026-09-04issueIssued notice
  26. 2026-06-04proposal43 value proposals approved togetherone review action inferred from a shared reviewer and instant — the graph records one activity per proposal
  27. 2026-06-04publicationPublication — backfill
  28. 2026-04-26revisionRevision 1
  29. 2026-04-26absenceSearched PubMed for "2-oxo-PCE O-PCE ketamine analogue acute poisoning emergency" — no results
  30. 2026-04-26absenceSearched PubMed for "deschloro-N-ethyl-ketamine O-PCE Hong Kong acute intoxication" — no results
  31. 2026-04-26absenceSearched PubMed for "2-oxo-PCE NMDA antagonist dissociative" — no results
  32. 2026-04-26absenceSearched ClinicalTrials.gov for "O-PCE eticyclidone dissociative" — no results
  33. 2026-04-26genGeneration — pipeline-v5 · with 2 morepipeline-v5
  34. 2026-04-26rungeneration run

The same entries, as forms: six forms.