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1Provenance card

the boundary, as counts

Sources

2522 with DOI

1 strong · 18 moderate · 6 weak

Compilations

12026-04-26T19:45:03.334Z

pipeline-v5 · prompt hash not recorded — run predates 2026-09

Decisions

44last ruled 2026-06-04

0 awaiting a ruling

Issued documents

42026-10-19T20:33:18.417Z

notice · info card · emergency

Searches

191 with no results

queries and counts on the build

Claims checked

9686 supported

86 supported · 10 not

Correspondence

0received

consent field ships in Phase 4

Edges

293

derivations recorded for this entity

Complete over 25 sources, 1 compilation, and 44 decisions.Not here: the private journal (never).Working material — drafts, discards, unsupported claims — is listed below and readable on the working page.Cite: psychedex.org/substances/nep/archive

Timeline

what happened, newest first — claims, searches and artifacts stay inside Build

  1. 2026-10-19issueIssued info_card
  2. 2026-09-24srcAnalytical Challenges in Detecting NPS in Anti-Doping: A Proof-of-Concept Involving Pentedrone Metabolite
  3. 2026-09-24srcStructure-Activity Relationships of Synthetic Cathinones.
  4. 2026-09-24srcDesigner drugs: mechanism of action and adverse effects
  5. 2026-09-24srcSynthesis of emerging cathinones and validation of a SPE GC-MS method for their simultaneous quantification in blood.
  6. 2026-09-24srcSynthetic cathinones in drug-facilitated sexual assault: A case report involving N-ethylpentedrone
  7. 2026-09-24srcNew psychoactive substances - 96 cases of deaths related to their use based on forensic toxicological practice.
  8. 2026-09-24srcMetabolic profile of N-ethylhexedrone, N-ethylpentedrone, and 4-chloromethcathinone in urine samples by UHPLC-QTOF-HRMS.
  9. 2026-09-24srcComparison of authentic urine N-ethylpentedrone metabolites to predicted in silico and in vitro human hepatocyte metabolism.
  10. 2026-09-24srcFirst enantioselective determination of N-ethylpentedrone and its major phase-1 metabolites using supercritical fluid chromatography coupled with tandem mass spectrometry and its application to human oral fluid and urine samples.
  11. 2026-09-24srcMonoamine transporter and receptor interaction profiles of a new series of designer cathinones
  12. 2026-09-24srcRole of amino terminal substitutions in the pharmacological, rewarding and psychostimulant profiles of novel synthetic cathinones.
  13. 2026-09-24srcStructure-activity relationships for locomotor stimulant effects and monoamine transporter interactions of substituted amphetamines and cathinones.
  14. 2026-09-24srcLocomotor stimulant and drug discrimination effects of five synthetic cathinones in rodents
  15. 2026-09-24srcRepeated administration of N-ethyl-pentedrone induces increased aggression and impairs social exploration after withdrawal in mice
  16. 2026-09-24srcThe combination of ethanol with mephedrone increases the signs of neurotoxicity and impairs neurogenesis and learning in adolescent CD-1 mice.
  17. 2026-09-24srcToxicological Analysis of Cases of Mixed Poisonings with Synthetic Cathinones and Other Drugs of Abuse.
  18. 2026-09-24srcSynthetic Cathinones in Belgium: Two Case Reports with Different Outcomes Observed in the Emergency Room
  19. 2026-09-24srcThe new stimulant designer compound pentedrone exhibits rewarding properties and affects dopaminergic activity.
  20. 2026-09-24srcPharmacological characterization of designer cathinones in vitro
  21. 2026-09-24srcUnderreporting of synthetic cathinone poisoning with clinical immunoassays: An experimental and observational study.
  22. 2026-09-24srcEmerging drugs of abuse: current perspectives on substituted cathinones
  23. 2026-09-24srcThe Pharmacological Profile of Second Generation Pyrovalerone Cathinones and Related Cathinone Derivative.
  24. 2026-09-24srcSchedules of Controlled Substances: Placement of N-Ethylhexedrone, alpha-Pyrrolidinohexanophenone, 4-Methyl-alpha-ethylaminopentiophenone, 4′-Methyl-alpha-pyrrolidinohexiophenone, alpha-Pyrrolidinoheptaphenone, and 4′-Chloro-alpha-pyrrolidinovalerophenone in Schedule I
  25. 2026-09-24srcEUDA initial report on the new psychoactive substance N-ethylnorpentedrone (NEP)
  26. 2026-09-24srcN-Ethylpentedrone PubChem Entry (CID 205593)
  27. 2026-09-04issueIssued emergency
  28. 2026-09-04issueIssued info_card
  29. 2026-09-04issueIssued notice
  30. 2026-06-04proposal42 value proposals approved togetherone review action inferred from a shared reviewer and instant — the graph records one activity per proposal
  31. 2026-06-04publicationPublication — backfill
  32. 2026-04-26revisionRevision 1
  33. 2026-04-26absenceSearched ClinicalTrials.gov for "N-ethylpentedrone synthetic cathinone" — no results
  34. 2026-04-26genGeneration — pipeline-v5 · with 2 morepipeline-v5
  35. 2026-04-26rungeneration run

The same entries, as forms: six forms.