Modafinil
1Provenance card
the boundary, as counts
Sources
4328 with DOI
28 strong · 12 moderate · 3 weak
Compilations
12026-04-24T18:42:01.931Z
pipeline-v5 · prompt hash not recorded — run predates 2026-09
Decisions
32last ruled 2026-06-04
0 awaiting a ruling
Issued documents
42026-10-19T20:33:07.141Z
notice · info card · emergency
Searches
220 with no results
queries and counts on the build
Claims checked
10834 supported
34 supported · 74 not
Correspondence
0received
consent field ships in Phase 4
Edges
326
derivations recorded for this entity
Complete over 43 sources, 1 compilation, and 32 decisions.Not here: the private journal (never).Working material — drafts, discards, unsupported claims — is listed below and readable on the working page.Cite: psychedex.org/substances/modafinil/archive
Timeline
what happened, newest first — claims, searches and artifacts stay inside Build
- 2026-10-19issueIssued info_card
- 2026-09-07srcEffects of modafinil on dopamine and dopamine transporters in the male human brain: clinical implications.
- 2026-09-07srcDirect comparison of the acute subjective, emotional, autonomic, and endocrine effects of MDMA, methylphenidate, and modafinil in healthy subjects.
- 2026-09-07srcModafinil, an atypical CNS stimulant?
- 2026-09-07srcModulating the immune response with the wake-promoting drug modafinil: A potential therapeutic approach for inflammatory disorders.
- 2026-09-07srcA double blind, placebo controlled trial of modafinil for the treatment of cocaine dependence without co-morbid alcohol dependence.
- 2026-09-07srcModafinil for cognitive neuroenhancement in healthy non-sleep-deprived subjects: A systematic review.
- 2026-09-07srcModafinil improves attentional performance in healthy, non-sleep deprived humans at doses not inducing hyperarousal across species.
- 2026-09-07srcModafinil: its discovery, the early European and North American experience in the treatment of narcolepsy and idiopathic hypersomnia, and its subsequent use in other medical conditions.
- 2026-09-07srcEfficacy and safety of modafinil in patients with idiopathic hypersomnia without long sleep time: a multicenter, randomized, double-blind, placebo-controlled, parallel-group comparison study.
- 2026-09-07srcPitolisant-supported bridging during drug holidays to deal with tolerance to modafinil in patients with narcolepsy.
- 2026-09-07srcAn updated systematic review and meta-analysis of modafinil for excessive daytime sleepiness in narcolepsy.
- 2026-09-07srcPitolisant versus placebo or modafinil in patients with narcolepsy: a double-blind, randomised trial.
- 2026-09-07srcModulatory effects of modafinil on neural circuits regulating emotion and cognition.
- 2026-09-07srcDopamine Transporter Correlates and Occupancy by Modafinil in Cocaine-Dependent Patients: A Controlled PET Study.
- 2026-09-07srcModafinil: a review of neurochemical actions and effects on cognition.
- 2026-09-07srcDose-dependent subacute cardiovascular effects of modafinil in rats.
- 2026-09-07srcDifferential expression of D2 receptor isoforms in the mesocorticolimbic system after treatment with modafinil.
- 2026-09-07srcA randomized, double-blind, placebo-controlled study of modafinil film-coated tablets in children and adolescents with attention-deficit/hyperactivity disorder.
- 2026-09-07srcEfficacy of THN102 (a combination of modafinil and flecainide) on vigilance and cognition during 40-hour total sleep deprivation.
- 2026-09-07srcEfficacy and tolerability of adjunctive modafinil/armodafinil in bipolar depression: A meta-analysis of randomized controlled trials.
- 2026-09-07srcComparative efficacy of new wake-promoting agents for narcolepsy - a network meta-analysis.
- 2026-09-07srcEfficacy of modafinil on fatigue and excessive daytime sleepiness associated with neurological disorders: a systematic review and meta-analysis.
- 2026-09-07srcDopaminergic D1 and D2 receptors are essential for the arousal effect of modafinil.
- 2026-09-07srcComparative efficacy and safety of multiple wake-promoting agents for the treatment of excessive daytime sleepiness in narcolepsy: A network meta-analysis.
- 2026-09-07srcPharmacokinetic profile of armodafinil in healthy subjects: pooled analysis of data from three randomized studies.
- 2026-09-07srcPsychostimulant Use Disorder, an Unmet Therapeutic Goal: Can Modafinil Narrow the Gap?
- 2026-09-07srcThe Structural Basis of the Activity Cliff in Modafinil-Based Dopamine Transporter Inhibitors.
- 2026-09-07srcModafinil for Promoting Wakefulness in Critically Ill Patients: Current Evidence and Perspectives.
- 2026-09-07srcNarcolepsy in orexin knockout mice: molecular genetics of sleep regulation.
- 2026-09-07srcModafinil, d-amphetamine and placebo during 64 hours of sustained mental work.
- 2026-09-07srcDopaminergic role in stimulant-induced wakefulness.
- 2026-09-07srcClinical pharmacokinetic profile of modafinil.
- 2026-09-07srcModafinil more effectively induces wakefulness in orexin-null mice than in wild-type littermates.
- 2026-09-07srcModafinil elicits sympathomedullary activation.
- 2026-09-07srcA systematic review of modafinil: Potential clinical uses and mechanisms of action.
- 2026-09-07srcA placebo-controlled evaluation of adjunctive modafinil in the treatment of bipolar depression.
- 2026-09-07srcPractice parameters for the treatment of narcolepsy and other hypersomnias of central origin.
- 2026-09-07srcApproved and investigational uses of modafinil: an evidence-based review.
- 2026-09-07srcPharmacokinetic study of modafinil in relation to gender and ethnicity in healthy young Chinese volunteers.
- 2026-09-07srcModafinil as a replacement for dextroamphetamine for sustaining alertness in military helicopter pilots.
- 2026-09-07srcModafinil - StatPearls
- 2026-09-07srcSchedules of Controlled Substances: Placement of Modafinil Into Schedule IV
- 2026-09-07srcModafinil FDA Prescribing Information (Provigil label)
- 2026-09-04issueIssued emergency
- 2026-09-04issueIssued info_card
- 2026-09-04issueIssued notice
- 2026-06-04proposal30 value proposals approved togetherone review action inferred from a shared reviewer and instant — the graph records one activity per proposal
- 2026-06-04publicationPublication — backfill
- 2026-04-24revisionRevision 1
- 2026-04-24genGeneration — pipeline-v5pipeline-v5
- 2026-04-24rungeneration run
The same entries, as forms: six forms.