Melatonin Facts
Sedative;
Dose and durationby route · individual sensitivity varies
Oral(mg)
Threshold< 0.25 mgLight0.5 – 1 mgCommon1 – 3 mgStrong3 – 6 mgHeavy6+ mg
Starts in 5 – 20 minLasts 3 – 6 hours
Body and dependence
- Acute toxicity
- Negligible
- Chronic toxicity
- Negligible
- Physical dependence
- Not assessed
- Psychological dependence
- Not assessed
- Withdrawal
- Not assessed
- Compulsive redosing
- Not assessed
Tolerance
- Builds
- After prolonged and repeated usage
- Fully resets after
- 14 days
Effectslikely at a common dose
- Body
- none likely · 4 possible, including Headache
- Feeling
- none likely · 2 possible
- Self
- none likely · 1 possible, including Depersonalization
Who shouldn't take it
None recorded. Not listed never means safe to take.
Combinations60 recorded
Caution (25)
See full page: psychedex.org/substances/melatonin
Not graded (35)
Not listed never means safe.
Seek help immediately if
No emergency profile is recorded for this substance. Not recorded never means no risk.
988 Suicide & Crisis LifelineFireside Project: 62-FIRESIDE
Version r1 · Not medical advice
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