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Entity
Melatonin
PSX-0241
Open Beta
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Common namesMelatonin
Substitutive nameN-Acetyl-5-methoxytryptamine
ChemicalTryptamine
PharmacologicalMelatonin MT1/MT2 receptor agonist
Threshold
< 0.25 mg
Light
0.5 – 1 mg
Common
1 – 3 mg
Strong
3 – 6 mg
Heavy
6+ mg
Onset
5 – 20 min
Come up
20 – 70 min
Peak
1 – 2 hours
Offset
2 – 3 hours
Total:3 – 6 hours
minlowmodhigh
Acute
Chronic
Physical
Psych.
Withdrawalnot assessed
Buildupafter prolonged and repeated usage
Full reset14 days
caution25
Dosage varies by body weight, tolerance & metabolism · Not medical advice · Terms
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Melatonin
Effects (8)
Dependence
not habit-forming
experience reports
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First-person accounts of subjective effects, timing, and outcomes — submitted for harm reduction.
Last updated Mar 17, 2026Report an issue