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1Provenance card

the boundary, as counts

Sources

3326 with DOI

1 strong · 23 moderate · 9 weak

Compilations

12026-05-11T14:14:27.789Z

pipeline-v5 · prompt hash not recorded — run predates 2026-09

Decisions

29last ruled 2026-06-04

0 awaiting a ruling

Issued documents

52026-10-19T20:32:24.016Z

notice · info card · emergency

Searches

181 with no results

queries and counts on the build

Claims checked

18815 supported

15 supported · 173 not

Correspondence

0received

consent field ships in Phase 4

Edges

471

derivations recorded for this entity

Complete over 33 sources, 1 compilation, and 29 decisions.Not here: the private journal (never).Working material — drafts, discards, unsupported claims — is listed below and readable on the working page.Cite: psychedex.org/substances/jwh-073/archive

Timeline

what happened, newest first — claims, searches and artifacts stay inside Build

  1. 2026-10-19issueIssued emergency
  2. 2026-10-19issueIssued info_card
  3. 2026-09-07srcMonitoring of herbal mixtures potentially containing synthetic cannabinoids as psychoactive compounds
  4. 2026-09-07srcToxicological profiles of selected synthetic cannabinoids showing high binding affinities to the cannabinoid receptor subtype CB1
  5. 2026-09-07srcAdverse Effects of Synthetic Cannabinoids: Management of Acute Toxicity and Withdrawal
  6. 2026-09-07srcCardiotoxicity associated with the synthetic cannabinoid, K9, with laboratory confirmation
  7. 2026-09-07srcMonohydroxylated metabolites of the K2 synthetic cannabinoid JWH-073 retain intermediate to high cannabinoid 1 receptor (CB1R) affinity and exhibit neutral antagonist to partial agonist activity
  8. 2026-09-07srcMonitoring of urinary metabolites of JWH-018 and JWH-073 in legal cases
  9. 2026-09-07srcInfluence of structural characteristics on the binding of synthetic cannabinoids from the JWH family to the CB1 receptor: A computational study
  10. 2026-09-07srcMoving around the molecule: relationship between chemical structure and in vivo activity of synthetic cannabinoids
  11. 2026-09-07srcMethodology for controlled administration of smoked synthetic cannabinoids JWH-018 and JWH-073
  12. 2026-09-07srcEffect of JWH-250, JWH-073 and their interaction on tetrad, sensorimotor, neurological and neurochemical responses in mice
  13. 2026-09-07srcHuman metabolites of synthetic cannabinoids JWH-018 and JWH-073 bind with high affinity and act as potent agonists at cannabinoid type-2 receptors
  14. 2026-09-07srcA sensitive GC-EIMS method for simultaneous detection and quantification of JWH-018 and JWH-073 carboxylic acid and hydroxy metabolites in urine
  15. 2026-09-07srcDetection Times of Carboxylic Acid Metabolites of the Synthetic Cannabinoids JWH-018 and JWH-073 in Human Urine
  16. 2026-09-07srcSensitivity to delta9-tetrahydrocannabinol is selectively enhanced in beta-arrestin2 -/- mice
  17. 2026-09-07srcK2 toxicity: fatal case of psychiatric complications following AM2201 exposure
  18. 2026-09-07srcAcute toxicity due to the confirmed consumption of synthetic cannabinoids: clinical and laboratory findings
  19. 2026-09-07src"Spice" and "K2" herbal highs: a case series and systematic review of the clinical effects and biopsychosocial implications of synthetic cannabinoid use in humans
  20. 2026-09-07srcConjugation of synthetic cannabinoids JWH-018 and JWH-073, metabolites by human UDP-glucuronosyltransferases
  21. 2026-09-07srcDifferential drug-drug interactions of the synthetic Cannabinoids JWH-018 and JWH-073: implications for drug abuse liability and pain therapy
  22. 2026-09-07srcThe adverse health effects of synthetic cannabinoids with emphasis on psychosis-like effects
  23. 2026-09-07srcThree cases of spice exposure
  24. 2026-09-07srcA systematic review of adverse events arising from the use of synthetic cannabinoids and their associated treatment
  25. 2026-09-07srcBehavioral and Pharmacokinetic Profile of Indole-Derived Synthetic Cannabinoids JWH-073 and JWH-210 as Compared to the Phytocannabinoid Delta9-THC in Rats
  26. 2026-09-07srcSynthetic cannabinoid JWH-073 alters both acute behavior and in vivo/vitro electrophysiological responses in mice
  27. 2026-09-07srcQSAR Model for Predicting the Cannabinoid Receptor 1 Binding Affinity and Dependence Potential of Synthetic Cannabinoids
  28. 2026-09-07srcSynthetic cannabinoids: the multi-organ failure and metabolic derangements associated with getting high
  29. 2026-09-07srcStructure-activity relationships for 1-alkyl-3-(1-naphthoyl)indoles at the cannabinoid CB(1) and CB(2) receptors
  30. 2026-09-07srcStratification of Cannabinoid 1 Receptor (CB1R) Agonist Efficacy: Manipulation of CB1R Density through Use of Transgenic Mice
  31. 2026-09-07srcKi binding affinity values for JWH-073 at CB1 (8.9 nM) and CB2 (38 nM) receptors
  32. 2026-09-07srcDEA Temporary Scheduling of Five Synthetic Cannabinoids Including JWH-073
  33. 2026-09-07srcPermanent Scheduling of Five Synthetic Cannabinoids Including JWH-073
  34. 2026-09-07srcJWH-073 SMILES and Chemical Structure
  35. 2026-09-07srcJWH-073 Discovery - John W. Huffman, Clemson University
  36. 2026-09-04issueIssued emergency
  37. 2026-09-04issueIssued info_card
  38. 2026-09-04issueIssued notice
  39. 2026-06-04proposal27 value proposals approved togetherone review action inferred from a shared reviewer and instant — the graph records one activity per proposal
  40. 2026-06-04publicationPublication — backfill
  41. 2026-05-11revisionRevision 1
  42. 2026-05-11absenceSearched ClinicalTrials.gov for "JWH-073 synthetic cannabinoid" — no results
  43. 2026-05-11genGeneration — pipeline-v5 · with 3 morepipeline-v5
  44. 2026-05-11rungeneration run

The same entries, as forms: six forms.