Ibogaine
1Provenance card
the boundary, as counts
Sources
4226 with DOI
5 strong · 33 moderate · 4 weak
Compilations
12026-04-26T03:53:45.177Z
pipeline-v5 · prompt hash not recorded — run predates 2026-09
Decisions
32last ruled 2026-06-04
0 awaiting a ruling
Issued documents
42026-10-19T20:32:19.117Z
notice · info card · emergency
Searches
244 with no results
queries and counts on the build
Claims checked
9876 supported
76 supported · 22 not
Correspondence
0received
consent field ships in Phase 4
Edges
307
derivations recorded for this entity
Complete over 42 sources, 1 compilation, and 32 decisions.Not here: the private journal (never).Working material — drafts, discards, unsupported claims — is listed below and readable on the working page.Cite: psychedex.org/substances/ibogaine/archive
Timeline
what happened, newest first — claims, searches and artifacts stay inside Build
- 2026-10-19issueIssued info_card
- 2026-09-24srcAscending Single-Dose, Double-Blind, Placebo-Controlled Safety Study of Noribogaine in Opioid-Dependent Patients
- 2026-09-24srcAscending-dose study of noribogaine in healthy volunteers: pharmacokinetics, pharmacodynamics, safety, and tolerability
- 2026-09-24srcInfluence of CYP2D6 activity on the pharmacokinetics and pharmacodynamics of a single 20 mg dose of ibogaine in healthy volunteers
- 2026-09-24srchERG Blockade by Iboga Alkaloids
- 2026-09-24srcAnti-addiction Drug Ibogaine Prolongs the Action Potential in Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes
- 2026-09-24srcMystical experiences during magnesium-Ibogaine are associated with improvements in PTSD symptoms in veterans
- 2026-09-24srcEffects of low dose ibogaine on subjective mood state and psychological performance
- 2026-09-24srcA systematic literature review of clinical trials and therapeutic applications of ibogaine
- 2026-09-24srcThe therapeutic effects of psychedelics for opioid use disorder: A systematic review of clinical studies
- 2026-09-24srcEfficient Access to the Iboga Skeleton: Optimized Procedure to Obtain Voacangine from Voacanga africana Root Bark
- 2026-09-24srcOxa-Iboga alkaloids lack cardiac risk and disrupt opioid use in animal models
- 2026-09-24srcMagnesium-ibogaine therapy in veterans with traumatic brain injuries
- 2026-09-24srcIbogaine and addiction in the animal model, a systematic review and meta-analysis
- 2026-09-24srcToxicokinetics of ibogaine and noribogaine in a patient with prolonged multiple cardiac arrhythmias after ingestion of internet purchased ibogaine
- 2026-09-24srcPsychedelic Therapy: A Primer for Primary Care Clinicians-Ibogaine
- 2026-09-24srcSafety of ibogaine administration in detoxification of opioid-dependent individuals: a descriptive open-label observational study
- 2026-09-24srcNoribogaine, but not 18-MC, exhibits similar actions as ibogaine on GDNF expression and ethanol self-administration
- 2026-09-24srcThe pharmacokinetics and pharmacodynamics of ibogaine in opioid use disorder patients
- 2026-09-24srcIbogaine, an anti-addictive drug: pharmacology and time to go further in development
- 2026-09-24srcEffect of Iboga alkaloids on µ-opioid receptor-coupled G protein activation
- 2026-09-24srcIbogaine/Noribogaine in the Treatment of Substance Use Disorders: A Systematic Review of the Current Literature
- 2026-09-24srcHow toxic is ibogaine?
- 2026-09-24srcIbogaine Detoxification Transitions Opioid and Cocaine Abusers Between Dependence and Abstinence
- 2026-09-24srcDrug Transporters ABCB1 (P-gp) and OATP, but not Drug-Metabolizing Enzyme CYP3A4, Affect the Pharmacokinetics of the Psychoactive Alkaloid Ibogaine and its Metabolites
- 2026-09-24srcIbogaine's potential role in supporting reward system recovery across diagnostic boundaries
- 2026-09-24srcThe anti-addiction drug ibogaine and the heart: a delicate relation
- 2026-09-24srcTreatment of acute opioid withdrawal with ibogaine
- 2026-09-24srcDevelopment of novel medications for drug addiction. The legacy of an African shrub
- 2026-09-24srcA dose-response study of ibogaine-induced neuropathology in the rat cerebellum
- 2026-09-24src18-Methoxycoronaridine (18-MC) and ibogaine: comparison of antiaddictive efficacy, toxicity, and mechanisms of action
- 2026-09-24srcMechanisms of action of ibogaine: relevance to putative therapeutic effects and development of a safer iboga alkaloid congener
- 2026-09-24srcMechanisms of action of ibogaine and harmaline congeners based on radioligand binding studies
- 2026-09-24srcGlial cell line-derived neurotrophic factor mediates the desirable actions of the anti-addiction drug ibogaine against alcohol consumption
- 2026-09-24srcReceptor binding profile suggests multiple mechanisms of action are responsible for ibogaine's putative anti-addictive activity
- 2026-09-24srcIbogaine block of the NMDA receptor: in vitro and in vivo studies
- 2026-09-24srcIbogaine neurotoxicity: a re-evaluation
- 2026-09-24srcIbogaine and cocaine abuse: pharmacological interactions at dopamine and serotonin receptors
- 2026-09-24srcEvidence for roles of kappa-opioid and NMDA receptors in the mechanism of action of ibogaine
- 2026-09-24srcThe olivocerebellar projection mediates ibogaine-induced degeneration of Purkinje cells
- 2026-09-24srcMechanisms of antiaddictive actions of ibogaine
- 2026-09-24srcIbogaine legal status and scheduling history
- 2026-09-24srcState-by-State Ibogaine Legislation tracker
- 2026-09-04issueIssued emergency
- 2026-09-04issueIssued info_card
- 2026-09-04issueIssued notice
- 2026-06-04proposal30 value proposals approved togetherone review action inferred from a shared reviewer and instant — the graph records one activity per proposal
- 2026-06-04publicationPublication — backfill
- 2026-04-26revisionRevision 1
- 2026-04-26absenceSearched web for "ibogaine physical properties CAS LD50" — no results
- 2026-04-26absenceSearched PubMed for "ibogaine LD50 lethal dose toxicity animal" — no results
- 2026-04-26absenceSearched PubChem web for "ibogaine CAS melting point logP LD50" — no results
- 2026-04-26absenceSearched PubMed for "ibogaine LD50 lethal dose toxicity animal study mouse rat" — no results
- 2026-04-26genGeneration — pipeline-v5pipeline-v5
- 2026-04-26rungeneration run
The same entries, as forms: six forms.