Hydrocodone
1Provenance card
the boundary, as counts
Sources
3829 with DOI
16 strong · 18 moderate · 4 weak
Compilations
12026-05-09T19:02:08.342Z
pipeline-v5 · prompt hash not recorded — run predates 2026-09
Decisions
34last ruled 2026-06-04
0 awaiting a ruling
Issued documents
42026-10-19T20:32:16.131Z
notice · info card · emergency
Searches
212 with no results
queries and counts on the build
Claims checked
6757 supported
57 supported · 10 not
Correspondence
0received
consent field ships in Phase 4
Edges
240
derivations recorded for this entity
Complete over 38 sources, 1 compilation, and 34 decisions.Not here: the private journal (never).Working material — drafts, discards, unsupported claims — is listed below and readable on the working page.Cite: psychedex.org/substances/hydrocodone/archive
Timeline
what happened, newest first — claims, searches and artifacts stay inside Build
- 2026-10-19issueIssued info_card
- 2026-09-07srcMedications for Opioid Use Disorder, Opioid Withdrawal, and Opioid Overdose: A Review.
- 2026-09-07srcCYP2D6 Phenotypes and Emergency Department Visits Among Patients Receiving Opioid Treatment
- 2026-09-07srcCYP2D6-Guided Opioid Management and Postoperative Pain Control: A Randomized Clinical Trial
- 2026-09-07srcLong-term opioid management for chronic noncancer pain
- 2026-09-07srcIncreasing deaths from opioid analgesics in the United States
- 2026-09-07srcPharmacotherapy research landscape and knowledge gaps of opioids in maternal and pediatric populations
- 2026-09-07srcComparative Rates of Mortality and Serious Adverse Effects Among Commonly Prescribed Opioid Analgesics
- 2026-09-07srcTrends in Medical Use of Opioids in the U.S., 2006-2016
- 2026-09-07srcEffects of paroxetine, a CYP2D6 inhibitor, on the pharmacokinetic properties of hydrocodone after coadministration with a single-entity, once-daily, extended-release hydrocodone tablet
- 2026-09-07srcMechanisms of tramadol-related neurotoxicity in the rat: Does diazepam/tramadol combination play a worsening role in overdose?
- 2026-09-07srcUniform assessment and ranking of opioid mu receptor binding constants for selected opioid drugs
- 2026-09-07srcOpioid metabolism
- 2026-09-07srcClinical Pharmacogenetics Implementation Consortium Guidelines for Cytochrome P450 2D6 Genotype and Codeine Therapy: 2014 Update
- 2026-09-07srcAnalgesic efficacy of naproxen sodium versus hydrocodone/acetaminophen in acute postsurgical dental pain: a randomized, double-blind, placebo-controlled trial
- 2026-09-07srcDrug Enforcement Administration Rescheduling of Hydrocodone Combination Products Is Associated With Changes in Physician Pain Management Prescribing Preferences
- 2026-09-07srcUrinary hydrocodone and metabolite distributions in pain patients
- 2026-09-07srcSuzetrigine, a Nonopioid NaV1.8 Inhibitor for Treatment of Moderate-to-severe Acute Pain: Two Phase 3 Randomized Clinical Trials
- 2026-09-07srcEvaluating the stability of opioid efficacy over 12 months in patients with chronic noncancer pain who initially demonstrate benefit from extended release oxycodone or hydrocodone
- 2026-09-07srcEvaluation of Hydrocodone/Acetaminophen for Pediatric Laceration Repair: A Randomized Trial
- 2026-09-07srcParent and Metabolite Opioid Drug Concentrations in Unintentional Deaths Involving Opioid and Benzodiazepine Combinations
- 2026-09-07srcBenzodiazepines: a major component in unintentional prescription drug overdoses with opioid analgesics.
- 2026-09-07srcImpact of Hydrocodone Rescheduling on Dental Prescribing of Opioids
- 2026-09-07srcSingle-dose pharmacokinetics of 2 or 3 tablets of biphasic immediate-release/extended-release hydrocodone bitartrate/acetaminophen (MNK-155) under fed and fasted conditions
- 2026-09-07srcLack of Influence by CYP3A4 and CYP3A5 Genotypes on Pain Relief by Hydrocodone in Postoperative Cesarean Section Pain Management
- 2026-09-07srcThe Aftermath of Hydrocodone Rescheduling: Intentional and Unintended Consequences
- 2026-09-07srcEffects of food and alcohol on the pharmacokinetics of an oral, extended-release formulation of hydrocodone in healthy volunteers
- 2026-09-07srcOpioid Toxicity
- 2026-09-07srcEffects of Hydrocodone Rescheduling on Pain Management Practices Among Older Breast Cancer Patients
- 2026-09-07srcOpioid Epidemic in the United States
- 2026-09-07srcCYP2D6 and CYP3A4 involvement in the primary oxidative metabolism of hydrocodone by human liver microsomes
- 2026-09-07srcMu receptor binding of some commonly used opioids and their metabolites
- 2026-09-07srcAssociation Between Formulary Coverage and Use of Abuse-Deterrent Prescription Opioids, Risk for Abuse or Overdose, and Associated Healthcare Resource Utilization
- 2026-09-07srcDEA Final Rule Rescheduling Hydrocodone Combination Products from Schedule III to Schedule II
- 2026-09-07srcHydrocodone - Wikipedia
- 2026-09-07srcClinical trial NCT01333722 - Acute Pain Study Following Bunionectomy
- 2026-09-07srcMorphine Milligram Equivalents - CDC Clinical Practice Guideline Appendix
- 2026-09-07srcClinical trial NCT00402792 - Extended-Release Hydrocodone/Acetaminophen in Acute Pain Following Bunionectomy
- 2026-09-07srcGamma-Hydroxybutyrate Toxicity - StatPearls
- 2026-09-04issueIssued emergency
- 2026-09-04issueIssued info_card
- 2026-09-04issueIssued notice
- 2026-06-04proposal32 value proposals approved togetherone review action inferred from a shared reviewer and instant — the graph records one activity per proposal
- 2026-06-04publicationPublication — backfill
- 2026-05-09revisionRevision 1
- 2026-05-09absenceSearched PubMed for "hydrocodone pharmacokinetics bioavailability half-life metabolism CYP" — no results
- 2026-05-09absenceSearched PubMed for "hydrocodone opioid receptor binding affinity Ki mu kappa" — no results
- 2026-05-09genGeneration — pipeline-v5 · with 2 morepipeline-v5
- 2026-05-09rungeneration run
The same entries, as forms: six forms.