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Psychedex

1Provenance card

the boundary, as counts

Sources

2621 with DOI

0 strong · 20 moderate · 6 weak

Compilations

12026-05-07T11:25:12.568Z

pipeline-v5 · prompt hash not recorded — run predates 2026-09

Decisions

43last ruled 2026-06-04

0 awaiting a ruling

Issued documents

52026-10-19T20:32:14.073Z

notice · info card · emergency

Searches

172 with no results

queries and counts on the build

Claims checked

6656 supported

56 supported · 10 not

Correspondence

0received

consent field ships in Phase 4

Edges

233

derivations recorded for this entity

Complete over 26 sources, 1 compilation, and 43 decisions.Not here: the private journal (never).Working material — drafts, discards, unsupported claims — is listed below and readable on the working page.Cite: psychedex.org/substances/hhc/archive

Timeline

what happened, newest first — claims, searches and artifacts stay inside Build

  1. 2026-10-19issueIssued emergency
  2. 2026-10-19issueIssued info_card
  3. 2026-10-02srcEvaluation of Cytochrome P450-Mediated Cannabinoid-Drug Interactions in Healthy Adult Participants
  4. 2026-10-02srcHexahydrocannabinol and closely related semi-synthetic cannabinoids: A comprehensive review
  5. 2026-10-02srcHuman metabolism of the semi-synthetic cannabinoids hexahydrocannabinol, hexahydrocannabiphorol and their acetates using hepatocytes and urine samples
  6. 2026-10-02srcInvestigation of the intrinsic cannabinoid activity of hemp-derived and semisynthetic cannabinoids with β-arrestin2 recruitment assays - and how this matters for the harm potential of seized drugs
  7. 2026-10-02srcCross-reactivity of the epimers of 11-nor-9-carboxy-hexahydrocannabinol, metabolites of hexahydrocannabinol, with panel tests for urinary Δ9-tetrahydrocannabinol metabolites
  8. 2026-10-02srcHexahydrocannabinol (HHC) use and harms in Ireland: New findings from the 2024 European Web Survey on Drugs
  9. 2026-10-02srcInhalation and oral administration of HHC products - Quantification of (9R)-, (9S)-Hexahydrocannabinol and metabolites in plasma and detectability in on-site drug tests
  10. 2026-10-02srcDetection of 11-nor-9-carboxy-hexahydrocannabinol (HHC-COOH) as metabolite of both hexahydrocannabinol (HHC) and Δ9-tetrahydrocannabinol (Δ9-THC) in routine forensic samples
  11. 2026-10-02srcProlonged sedation and unconsciousness after intoxication with the novel semisynthetic cannabinoid hexahydrocannabioctyl (HHC-C8): Two case descriptions
  12. 2026-10-02srcStudies Pertaining to the Emerging Cannabinoid Hexahydrocannabinol (HHC)
  13. 2026-10-02srcPreliminary pharmacokinetic and psychophysical investigations after controlled oral and inhalative consumption of hexahydrocannabinol (HHC)
  14. 2026-10-02srcLC-MS/MS analysis of 11-nor-9-carboxy-hexahydrocannabinol (HHC-COOH) and 11-hydroxy-hexahydrocannabinol (HHC-OH) for verification of hexahydrocannabinol (HHC) intake
  15. 2026-10-02srcAppearance of hexahydrocannabinols as recreational drugs and implications for cannabis drug testing - focus on HHC, HHC-P, HHC-O and HHC-H
  16. 2026-10-02srcHexahydrocannabinol on the Light Cannabis Market: The Latest 'New' Entry
  17. 2026-10-02srcHexahydrocannabinol: pharmacokinetics, systemic toxicity, and acute behavioral effects in Wistar rats
  18. 2026-10-02srcInsights into the human metabolism of hexahydrocannabinol by non-targeted liquid chromatography-high-resolution tandem mass spectrometry
  19. 2026-10-02srcCannabidiol-Derived Cannabinoids: The Unregulated Designer Drug Market Following the 2018 Farm Bill
  20. 2026-10-02srcAn emerging trend in Novel Psychoactive Substances (NPSs): designer THC
  21. 2026-10-02srcCannabinoid Interactions with Cytochrome P450 Drug Metabolism: a Full-Spectrum Characterization
  22. 2026-10-02srcUsing In Silico Molecular Docking to Explain Differences in Receptor Binding Behavior of HHC and THCV Isomers: Revealing New Binding Modes
  23. 2026-10-02srcLong-Lasting Cognitive and Physical Impairment After Recreational Use of the Semisynthetic Cannabinoid Hexahydrocannabinonyl (HHC-C9): A Case Report
  24. 2026-10-02srcThe importance of the orientation of the C9 substituent to cannabinoid activity
  25. 2026-10-02srcUS Patent 2419937: Marihuana Active Compounds
  26. 2026-10-02srcDEA Final Rule: Specific Listing for Hexahydrocannabinol, A Currently Controlled Schedule I Substance
  27. 2026-10-02srcWHO Expert Committee on Drug Dependence: Forty-seventh report - HHC Critical Review
  28. 2026-10-02srcSaturated Cannabinoids: Update on Synthesis Strategies and Biological Studies of These Emerging Cannabinoid Analogs
  29. 2026-09-04issueIssued emergency
  30. 2026-09-04issueIssued info_card
  31. 2026-09-04issueIssued notice
  32. 2026-06-04proposal41 value proposals approved togetherone review action inferred from a shared reviewer and instant — the graph records one activity per proposal
  33. 2026-06-04publicationPublication — backfill
  34. 2026-05-07revisionRevision 1
  35. 2026-05-07absenceSearched PubMed for "hexahydrocannabinol synthesis Adams 1940" — no results
  36. 2026-05-07absenceSearched PubMed for "hexahydrocannabinol HHC pharmacology receptor binding" — no results
  37. 2026-05-07genGeneration — pipeline-v5 · with 2 morepipeline-v5
  38. 2026-05-07rungeneration run

The same entries, as forms: six forms.