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1Provenance card

the boundary, as counts

Sources

3226 with DOI

15 strong · 13 moderate · 4 weak

Compilations

12026-04-20T11:42:41.827Z

pipeline-v5 · prompt hash not recorded — run predates 2026-09 · 1 other run

Decisions

54last ruled 2026-06-04

1 awaiting a ruling

Issued documents

42026-10-19T20:32:12.274Z

notice · info card · emergency

Searches

271 with no results

queries and counts on the build

Claims checked

7323 supported

23 supported · 50 not

Correspondence

0received

consent field ships in Phase 4

Edges

270

derivations recorded for this entity

Complete over 32 sources, 1 compilation, and 54 decisions.Not here: the private journal (never); 1 proposal awaiting a ruling (listed as pending only).Working material — drafts, discards, unsupported claims — is listed below and readable on the working page.Cite: psychedex.org/substances/heroin/archive

Timeline

what happened, newest first — claims, searches and artifacts stay inside Build

  1. 2026-10-19issueIssued info_card
  2. 2026-09-27runbrief run
  3. 2026-09-27revisionr1.a1
  4. 2026-09-24srcBuprenorphine for managing opioid withdrawal
  5. 2026-09-24srcBuprenorphine maintenance versus placebo or methadone maintenance for opioid dependence
  6. 2026-09-24srcMaintenance agonist treatments for opiate-dependent pregnant women
  7. 2026-09-24srcPostmortem tissue distribution of morphine and its metabolites in a series of heroin-related deaths
  8. 2026-09-24srcDifferent routes of heroin intake cause various heroin-induced leukoencephalopathies
  9. 2026-09-24srcPharmacokinetics and Pharmacodynamics of Intranasal Diacetylmorphine in Heroin-Assisted Treatment for Severe Opioid Use Disorder
  10. 2026-09-24srcInterventions to prevent HIV and Hepatitis C among people who inject drugs: Latest evidence of effectiveness from a systematic review (2011 to 2020)
  11. 2026-09-24srcEvaluation of poly-drug use in methadone-related fatalities using segmental hair analysis
  12. 2026-09-24srcUniform assessment and ranking of opioid mu receptor binding constants for selected opioid drugs
  13. 2026-09-24srcPublic health and international drug policy
  14. 2026-09-24src6-Monoacetylmorphine (6-MAM), Not Morphine, Is Responsible for the Rapid Neural Effects Induced by Intravenous Heroin
  15. 2026-09-24srcHeroin and its metabolites: relevance to heroin use disorder
  16. 2026-09-24srcComparative risk assessment of alcohol, tobacco, cannabis and other illicit drugs using the margin of exposure approach
  17. 2026-09-24srcDiacetylmorphine versus methadone for the treatment of opioid addiction
  18. 2026-09-24srcOpioid-free and opioid-sparing anesthesia
  19. 2026-09-24srcPrenatal Opioid Exposure and Neurodevelopmental Outcomes
  20. 2026-09-24srcHeroin metabolism in human blood and its impact for the design of an immunotherapeutic approach against heroin effects
  21. 2026-09-24srcMortality risk during and after opioid substitution treatment: systematic review and meta-analysis of cohort studies
  22. 2026-09-24srcScientific and political challenges in North America's first randomized controlled trial of heroin-assisted treatment for severe heroin addiction: rationale and design of the NAOMI study
  23. 2026-09-24srcHeroin on trial: systematic review and meta-analysis of randomised trials of diamorphine-prescribing as treatment for refractory heroin addiction
  24. 2026-09-24srcRecent Innovations to Detect and Intervene to Prevent Opioid Overdose Deaths
  25. 2026-09-24srcUnderstanding Heroin Overdose: A Study of the Acute Respiratory Depressant Effects of Injected Pharmaceutical Heroin
  26. 2026-09-24srcChronic Heroin Self-Administration Desensitizes mu Opioid Receptor-Activated G-Proteins in Specific Regions of Rat Brain
  27. 2026-09-24srcRapid Analysis of Drugs: Pilot Surveillance System to Detect Changes in the Illicit Drug Supply - Eight Syringe Services Programs, Maryland, 2021-2022
  28. 2026-09-24srcThe Major Medical Complications of Heroin Addiction
  29. 2026-09-24srcChasing the Dragon Syndrome: A Case of Toxic Leukoencephalopathy and Response to Intravenous Immunoglobulin
  30. 2026-09-24srcEvaluating long-term effects of heroin-assisted treatment: the results of a 6-year follow-up
  31. 2026-09-24srcDosage regimes in the prescription of heroin and other narcotics to chronic opioid addicts in Switzerland - Swiss national cohort study
  32. 2026-09-24srcDuration of analgesia in mice after heroin by two testing methods
  33. 2026-09-24srcHeroin legal scheduling: Schedule I (US), Class A Schedule 2 (UK)
  34. 2026-09-24srcHeroin drug profile
  35. 2026-09-24srcNIST WebBook: Diacetylmorphine CAS 561-27-3 Physical Properties
  36. 2026-09-04issueIssued emergency
  37. 2026-09-04issueIssued info_card
  38. 2026-09-04issueIssued notice
  39. 2026-07-03proposaldependence · taper
  40. 2026-06-04proposal50 value proposals approved togetherone review action inferred from a shared reviewer and instant — the graph records one activity per proposal
  41. 2026-06-04publicationPublication — backfill
  42. 2026-04-20revisionRevision 1
  43. 2026-04-20absenceSearched PubMed for "heroin synthesis history Heinrich Dreser Bayer 1898 diacetylmorphine" — no results
  44. 2026-04-20genGeneration — pipeline-v5 · with 2 morepipeline-v5
  45. 2026-04-20rungeneration run

The same entries, as forms: six forms.