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1Provenance card

the boundary, as counts

Sources

4633 with DOI

30 strong · 10 moderate · 6 weak

Compilations

12026-04-24T14:00:40.853Z

pipeline-v5 · prompt hash not recorded — run predates 2026-09 · 1 other run

Decisions

32last ruled 2026-06-04

1 awaiting a ruling

Issued documents

42026-10-19T20:32:08.332Z

notice · info card · emergency

Searches

181 with no results

queries and counts on the build

Claims checked

12789 supported

89 supported · 38 not

Correspondence

0received

consent field ships in Phase 4

Edges

365

derivations recorded for this entity

Complete over 46 sources, 1 compilation, and 32 decisions.Not here: the private journal (never); 1 proposal awaiting a ruling (listed as pending only).Working material — drafts, discards, unsupported claims — is listed below and readable on the working page.Cite: psychedex.org/substances/ghb/archive

Timeline

what happened, newest first — claims, searches and artifacts stay inside Build

  1. 2026-10-19issueIssued info_card
  2. 2026-10-02srcSedative-Hypnotic Agents That Impact Gamma-Aminobutyric Acid Receptors: Focus on Flunitrazepam, Gamma-Hydroxybutyric Acid, Phenibut, and Selank
  3. 2026-10-02srcInpatient GHB withdrawal management in an inner-city hospital in Sydney, Australia: a retrospective medical record review
  4. 2026-10-02srcClinician Preferences for Oxybate Treatment for Narcolepsy: Survey and Discrete Choice Experiment
  5. 2026-10-02srcBaclofen to Prevent Relapse in Gamma-Hydroxybutyrate (GHB)-Dependent Patients: A Multicentre, Open-Label, Non-Randomized, Controlled Trial
  6. 2026-10-02srcSodium oxybate: A comprehensive review of efficacy and safety in the treatment of alcohol withdrawal syndrome and alcohol dependence
  7. 2026-10-02srcGHB receptor targets in the CNS: focus on high-affinity binding sites
  8. 2026-10-02srcDetoxification with titration and tapering in gamma-hydroxybutyrate (GHB) dependent patients: The Dutch GHB monitor project
  9. 2026-10-02srcGamma-hydroxybutyrate in urine and serum: additional data supporting current cut-off recommendations
  10. 2026-10-02srcImplication of GHB in proactive drug facilitated crime in Paris, France
  11. 2026-10-02srcγ-Hydroxybutyric acid induces actions via the GABAB receptor in arousal and motor control-related nuclei
  12. 2026-10-02srcSodium oxybate reduces pain, fatigue, and sleep disturbance and improves functionality in fibromyalgia: results from a 14-week, randomized, double-blind, placebo-controlled study
  13. 2026-10-02srcGamma-hydroxybutyrate (GHB), 1,4-butanediol (1,4BD), and gamma-butyrolactone (GBL) intoxication: A state-of-the-art review
  14. 2026-10-02srcGamma-hydroxybutyrate to promote slow-wave sleep in major depressive disorder: a randomized crossover trial
  15. 2026-10-02srcMetabolism of γ-hydroxybutyrate in perfused rat livers
  16. 2026-10-02srcα4βδ GABA(A) receptors are high-affinity targets for γ-hydroxybutyric acid (GHB)
  17. 2026-10-02srcEvaluating the risk of toxicity and adverse drug interactions involving recreational GHB use and prescribed drugs
  18. 2026-10-02srcNocturnal Gamma-Hydroxybutyrate Reduces Cortisol-Awakening Response and Morning Kynurenine Pathway Metabolites in Healthy Volunteers
  19. 2026-10-02srcRelationship Between Postmortem Urine and Blood Concentrations of GHB Furnishes Useful Information to Help Interpret Drug Intoxication Deaths
  20. 2026-10-02srcTreatment of Gamma Hydroxybutyrate Withdrawal in a Pregnant Female: A Case Report
  21. 2026-10-02srcEfficacy and safety of sodium oxybate in alcohol-dependent patients with a very high drinking risk level
  22. 2026-10-02srcEFNS guidelines on management of narcolepsy
  23. 2026-10-02srcA Qualitative Approach in Understanding Illness Perception and Treatment Needs in Patients with Gamma Hydroxybutyrate Use Disorder
  24. 2026-10-02srcDevelopment of the Gamma-Hydroxybutyrate Withdrawal Symptom Questionnaire
  25. 2026-10-02srcSimultaneous stimulation of slow-wave sleep and growth hormone secretion by gamma-hydroxybutyrate in normal young men
  26. 2026-10-02srcBaclofen as relapse prevention in the treatment of Gamma-Hydroxybutyrate (GHB) dependence: an open label study
  27. 2026-10-02srcCharacterization and pharmacology of the GHB receptor
  28. 2026-10-02srcγ-Hydroxybutyric Acid (GHB) Pharmacokinetics and Pharmacodynamics: Semi-Mechanistic and Physiologically Relevant PK/PD Model
  29. 2026-10-02srcThe Drug of Abuse Gamma-Hydroxybutyric Acid Exhibits Tissue-Specific Nonlinear Distribution
  30. 2026-10-02srcγ-Hydroxybutyric Acid: Pharmacokinetics, Pharmacodynamics, and Toxicology
  31. 2026-10-02srcγ-Hydroxybutyric acid (GHB) is not an agonist of extrasynaptic GABAA receptors
  32. 2026-10-02srcDrugs in blood and urine samples from victims of suspected exposure to drink spiking: A prospective observational study from Oslo, Norway
  33. 2026-10-02srcGHB pharmacology and toxicology: acute intoxication, concentrations in blood and urine in forensic cases and treatment of the withdrawal syndrome
  34. 2026-10-02srcCognitive Impairment Following Clinical or Recreational Use of Gammahydroxybutyric Acid (GHB): A Systematic Review
  35. 2026-10-02srcFrom club drug to orphan drug: sodium oxybate (Xyrem) for the treatment of cataplexy
  36. 2026-10-02srcThe Xyrem risk management program
  37. 2026-10-02srcGHB (gamma-hydroxybutyrate) carrier-mediated transport across the blood-brain barrier
  38. 2026-10-02srcSodium oxybate for the treatment of narcolepsy
  39. 2026-10-02srcSynthesis and catabolism of gamma-hydroxybutyrate in SH-SY5Y human neuroblastoma cells: role of the aldo-keto reductase AKR7A2
  40. 2026-10-02srcGamma-aminobutyric acidB (GABAB)-receptor mediation of different in vivo effects of gamma-butyrolactone
  41. 2026-10-02srcImproving GHB withdrawal with baclofen: study protocol for a feasibility study for a randomised controlled trial
  42. 2026-10-02srcEvidence for the participation of a cytosolic NADP+-dependent oxidoreductase in the catabolism of gamma-hydroxybutyrate in vivo
  43. 2026-10-02srcWithdrawal syndrome following chronic use of gamma-hydroxybutyric acid (GHB)
  44. 2026-10-02srcDose-dependent absorption and elimination of gamma-hydroxybutyric acid in healthy volunteers
  45. 2026-10-02srcGamma-hydroxybutyrate: an emerging drug of abuse that causes physical dependence
  46. 2026-10-02srcThe gamma-hydroxybutyrate signalling system in brain: organization and functional implications
  47. 2026-10-02srcSchedules of Controlled Substances: Addition of Gamma-Hydroxybutyric Acid to Schedule I
  48. 2026-09-27runbrief run
  49. 2026-09-14revisionr1.a1
  50. 2026-09-04issueIssued emergency
  51. 2026-09-04issueIssued info_card
  52. 2026-09-04issueIssued notice
  53. 2026-07-03proposaldependence · taper
  54. 2026-06-04proposal28 value proposals approved togetherone review action inferred from a shared reviewer and instant — the graph records one activity per proposal
  55. 2026-06-04publicationPublication — backfill
  56. 2026-04-24revisionRevision 1
  57. 2026-04-24absenceSearched PubMed for "GHB overdose toxicity death case report respiratory depression" — no results
  58. 2026-04-24genGeneration — pipeline-v5 · with 3 morepipeline-v5
  59. 2026-04-24rungeneration run

The same entries, as forms: six forms.