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Psychedex

1Provenance card

the boundary, as counts

Sources

4119 with DOI

8 strong · 19 moderate · 14 weak

Compilations

12026-04-24T13:01:15.584Z

pipeline-v5 · prompt hash not recorded — run predates 2026-09 · 1 other run

Decisions

35last ruled 2026-06-04

0 awaiting a ruling

Issued documents

52026-10-19T20:31:32.665Z

notice · info card · emergency

Searches

310 with no results

queries and counts on the build

Claims checked

2021 supported

1 supported · 201 not

Correspondence

0received

consent field ships in Phase 4

Edges

525

derivations recorded for this entity

Complete over 41 sources, 1 compilation, and 35 decisions.Not here: the private journal (never).Working material — drafts, discards, unsupported claims — is listed below and readable on the working page.Cite: psychedex.org/substances/diphenhydramine/archive

Timeline

what happened, newest first — claims, searches and artifacts stay inside Build

  1. 2026-10-19issueIssued emergency
  2. 2026-10-19issueIssued info_card
  3. 2026-09-27runbrief run
  4. 2026-09-27revisionr1.a1
  5. 2026-09-24srcRestless Legs Syndrome: A Review.
  6. 2026-09-24srcToxicological identification of diphenhydramine (DPH) in suicide.
  7. 2026-09-24srcThe Use of Physostigmine by Toxicologists in Anticholinergic Toxicity.
  8. 2026-09-24srcA Literature Review of the Use of Sodium Bicarbonate for the Treatment of QRS Widening.
  9. 2026-09-24srcExtracorporeal Cardiopulmonary Resuscitation After Diphenhydramine Ingestion.
  10. 2026-09-24srcLidocaine for diphenhydramine-induced ventricular tachycardia: A case report.
  11. 2026-09-24srcPsilocybin for alcohol use disorder: Rationale and design considerations for a randomized controlled trial.
  12. 2026-09-24srcOpen channel block of NMDA receptors by diphenhydramine.
  13. 2026-09-24src[Diphenhydramine addiction and detoxification. A systematic review and case report].
  14. 2026-09-24srcAdverse events associated with diphenhydramine in children, 2008-2015.
  15. 2026-09-24srcA TikTok 'Benadryl Challenge' death - A case report and review of the literature.
  16. 2026-09-24srcDeath due to diphenhydramine toxicity: A 9-year review from the Cook County Medical Examiner's Office and a review of the literature.
  17. 2026-09-24srcInternational Union of Basic and Clinical Pharmacology. XCVIII. Histamine Receptors.
  18. 2026-09-24srcA Comparison of Resource Utilization in the Management of Anticholinergic Delirium Between Physostigmine and Nonantidote Therapy.
  19. 2026-09-24srcAnticholinergic burden and incident dementia: a Swedish nationwide case-control study.
  20. 2026-09-24srcIV Lipid Emulsion Infusion in the Treatment of Severe Diphenhydramine Overdose.
  21. 2026-09-24srcA History of Drug Discovery for Treatment of Nausea and Vomiting and the Implications for Future Research.
  22. 2026-09-24srcClinical Practice Guideline for the Pharmacologic Treatment of Chronic Insomnia in Adults: An American Academy of Sleep Medicine Clinical Practice Guideline.
  23. 2026-09-24srcDiphenhydramine Overdose: A Case Report and Topic Review of Prehospital Diagnosis and Treatment.
  24. 2026-09-24srcClassic histamine H1 receptor antagonists: a critical review of their metabolic and pharmacokinetic fate from a bird's eye view.
  25. 2026-09-24srcAcute pharmacological effects of temazepam, diphenhydramine, and valerian in healthy elderly subjects.
  26. 2026-09-24srcPharmacokinetics of diphenhydramine in healthy volunteers with a dimenhydrinate 25 mg chewing gum formulation.
  27. 2026-09-24srcSedation and memory: studies with a histamine H-1 receptor antagonist.
  28. 2026-09-24srcAntimuscarinic actions of antihistamines on the heart.
  29. 2026-09-24srcTrifluoperazine inhibits phosphoinositide hydrolysis as a histamine H1-receptor antagonist.
  30. 2026-09-24srcDiphenhydramine kinetics following intravenous, oral, and sublingual dimenhydrinate administration.
  31. 2026-09-24srcH1-histamine receptors on human astrocytoma cells.
  32. 2026-09-24srcClinical pharmacokinetics of H1-receptor antagonists (the antihistamines).
  33. 2026-09-24srcDiphenhydramine - PubChem Compound
  34. 2026-09-24srcEffects of terfenadine and diphenhydramine alone or in combination with diazepam or alcohol on psychomotor performance and subjective feelings.
  35. 2026-09-24src[Pharmacokinetics and bioavailability of diphenhydramine in man].
  36. 2026-09-24src[An anticholinergic syndrome with hallucinatory psychosis after diphenhydramine poisoning].
  37. 2026-09-24srcLack of sedative and cognitive effects of diphenhydramine and cyclobenzaprine in elderly volunteers.
  38. 2026-09-24srcDiphenhydramine toxicity: comparisons of postmortem findings in diphenhydramine-, cocaine-, and heroin-related deaths.
  39. 2026-09-24srcDiphenhydramine - StatPearls (NBK526010)
  40. 2026-09-24srcBenadryl: Allergy Relief for Millions - American Chemical Society
  41. 2026-09-24srcDiphenhydramine legal status by jurisdiction (Erowid/Wikipedia/ACS sources combined)
  42. 2026-09-24srcAustralia TGA Scheduling - Diphenhydramine Schedule 4 (July 1, 2026)
  43. 2026-09-24srcLD50 data for diphenhydramine hydrochloride (MSDS/safety data)
  44. 2026-09-24srcDiphenhydramine - Wikipedia
  45. 2026-09-24srcDiphenhydramine Toxicity - StatPearls (NBK557578)
  46. 2026-09-04issueIssued emergency
  47. 2026-09-04issueIssued info_card
  48. 2026-09-04issueIssued notice
  49. 2026-06-04proposal32 value proposals approved togetherone review action inferred from a shared reviewer and instant — the graph records one activity per proposal
  50. 2026-06-04publicationPublication — backfill
  51. 2026-04-24revisionRevision 1
  52. 2026-04-24genGeneration — pipeline-v5 · with 3 morepipeline-v5
  53. 2026-04-24rungeneration run

The same entries, as forms: six forms.