Dihydrocodeine
1Provenance card
the boundary, as counts
Sources
4015 with DOI
12 strong · 23 moderate · 5 weak
Compilations
12026-05-09T21:50:52.117Z
pipeline-v5 · prompt hash not recorded — run predates 2026-09
Decisions
34last ruled 2026-06-04
0 awaiting a ruling
Issued documents
42026-10-19T20:31:31.716Z
notice · info card · emergency
Searches
211 with no results
queries and counts on the build
Claims checked
9887 supported
87 supported · 11 not
Correspondence
0received
consent field ships in Phase 4
Edges
304
derivations recorded for this entity
Complete over 40 sources, 1 compilation, and 34 decisions.Not here: the private journal (never).Working material — drafts, discards, unsupported claims — is listed below and readable on the working page.Cite: psychedex.org/substances/dihydrocodeine/archive
Timeline
what happened, newest first — claims, searches and artifacts stay inside Build
- 2026-10-19issueIssued info_card
- 2026-09-07srcClinical Pharmacogenetics Implementation Consortium Guideline for CYP2D6, OPRM1, and COMT Genotypes and Select Opioid Therapy
- 2026-09-07srcThe management of dyspnea in cancer patients: a systematic review.
- 2026-09-07srcHighlighting the hidden dangers of a 'weak' opioid: Deaths following use of dihydrocodeine in England (2001-2020).
- 2026-09-07srcRelative toxicity of analgesics commonly used for intentional self-poisoning: A study of case fatality based on fatal and non-fatal overdoses
- 2026-09-07srcA randomized, double-blind, double-dummy comparison of short- and long-acting dihydrocodeine in chronic non-malignant pain.
- 2026-09-07srcComparative risk-benefit profiles of weak opioids in the treatment of osteoarthritis: a network meta-analysis.
- 2026-09-07srcDihydrocodeine Overdoses in a Neonate and in a 14-year-old Girl Who Were Both Genotyped as Cytochrome P450 2D6*1/*10-*36.
- 2026-09-07srcOpioid-induced inhibition of the human 5-HT and noradrenaline transporters in vitro: link to clinical reports of serotonin syndrome
- 2026-09-07srcThe impact of tramadol and dihydrocodeine treatment on quality of life of patients with cancer pain.
- 2026-09-07srcComparison of analgesic effects and patient tolerability of nabilone and dihydrocodeine for chronic neuropathic pain: randomised, crossover, double blind study.
- 2026-09-07srcA case report of inpatient detoxification after kratom dependence.
- 2026-09-07srcA systematic review of the use of opioid medication for those with moderate to severe cancer pain and renal impairment.
- 2026-09-07srcOpioid prescription patterns in Germany and the global opioid epidemic.
- 2026-09-07srcDihydrocodeine: safety concerns.
- 2026-09-07srcPharmacovigilance Signals of the Opioid Epidemic: Data Mining Methods in EudraVigilance and FAERS.
- 2026-09-07srcThe detection of dihydrocodeine and its main metabolites in cases of fatal overdose.
- 2026-09-07srcPharmacokinetics of opioids in liver disease.
- 2026-09-07srcPharmacokinetics of dihydrocodeine and its active metabolite after single and multiple oral dosing.
- 2026-09-07srcSingle dose dihydrocodeine for acute postoperative pain.
- 2026-09-07srcDose-related effects of controlled release dihydrocodeine on oro-cecal transit and pupillary light reflex. A study in human volunteers.
- 2026-09-07srcA systematic review of the use of opioids in the management of dyspnoea.
- 2026-09-07srcAffinities of dihydrocodeine and its metabolites to opioid receptors
- 2026-09-07srcTherapy with opioids in liver or renal failure.
- 2026-09-07srcActivation of G-proteins by morphine and codeine congeners: insights to the relevance of O- and N-demethylated metabolites at mu- and delta-opioid receptors.
- 2026-09-07srcDevelopment of a directly compressible poly(ethylene oxide) matrix for the sustained-release of dihydrocodeine bitartrate.
- 2026-09-07srcThe Leeds Evaluation of Efficacy of Detoxification Study (LEEDS) project.
- 2026-09-07srcPain and pain treatments in European palliative care units. A cross sectional survey.
- 2026-09-07srcCodeine and dihydrocodeine as substitute and alternative drugs.
- 2026-09-07src'Weak' opioid analgesics. Codeine, dihydrocodeine and tramadol: no less risky than morphine
- 2026-09-07srcTwo assays for dihydrocodeine in plasma and in urine and their use to determine the bioavailability of a controlled-release product.
- 2026-09-07srcEffects of renal insufficiency on the pharmacokinetics and pharmacodynamics of opioid analgesics.
- 2026-09-07srcPharmacokinetics of intravenous and oral dihydrocodeine and its acid metabolites.
- 2026-09-07srcDrug substitution treatment of heroin dependent patients with codeine preparations — treatment effects from the viewpoint of the physicians and patients.
- 2026-09-07srcDihydrocodeine: a new opioid substrate for the polymorphic CYP2D6 in humans.
- 2026-09-07srcAffinity profiles of morphine, codeine, dihydrocodeine and their glucuronides at opioid receptor subtypes.
- 2026-09-07srcA multiple dose comparison of ibuprofen and dihydrocodeine after third molar surgery.
- 2026-09-07srcPharmacokinetics of opioids in renal dysfunction.
- 2026-09-07srcCharacterization of the human cytochrome P450 enzymes involved in the metabolism of dihydrocodeine.
- 2026-09-07srcFormation and clearance of active and inactive metabolites of opiates in humans.
- 2026-09-07srcDihydrocodeine - Wikipedia
- 2026-09-04issueIssued emergency
- 2026-09-04issueIssued info_card
- 2026-09-04issueIssued notice
- 2026-06-04proposal32 value proposals approved togetherone review action inferred from a shared reviewer and instant — the graph records one activity per proposal
- 2026-06-04publicationPublication — backfill
- 2026-05-09revisionRevision 1
- 2026-05-09absenceSearched WebFetch for "FPM dose equivalents opioids" — no results
- 2026-05-09genGeneration — pipeline-v5 · with 2 morepipeline-v5
- 2026-05-09rungeneration run
The same entries, as forms: six forms.