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1Provenance card

the boundary, as counts

Sources

3911 with DOI

4 strong · 29 moderate · 6 weak

Compilations

12026-05-09T21:28:12.615Z

pipeline-v5 · prompt hash not recorded — run predates 2026-09

Decisions

29last ruled 2026-06-04

0 awaiting a ruling

Issued documents

42026-10-19T20:31:27.919Z

notice · info card · emergency

Searches

220 with no results

queries and counts on the build

Claims checked

2542 supported

2 supported · 252 not

Correspondence

0received

consent field ships in Phase 4

Edges

611

derivations recorded for this entity

Complete over 39 sources, 1 compilation, and 29 decisions.Not here: the private journal (never).Working material — drafts, discards, unsupported claims — is listed below and readable on the working page.Cite: psychedex.org/substances/dextropropoxyphene/archive

Timeline

what happened, newest first — claims, searches and artifacts stay inside Build

  1. 2026-10-19issueIssued info_card
  2. 2026-09-07srcPropoxyphene and the risk of out-of-hospital death
  3. 2026-09-07srcUniform assessment and ranking of opioid mu receptor binding constants for selected opioid drugs
  4. 2026-09-07srcCo-proxamol and suicide: preventing the continuing toll of overdose deaths
  5. 2026-09-07srcCo-proxamol withdrawal has reduced suicide from drugs in Scotland
  6. 2026-09-07srcDextropropoxyphene withdrawal from a French university hospital: impact on analgesic drug consumption
  7. 2026-09-07srcEffect of withdrawal of co-proxamol on prescribing and deaths from drug poisoning in England and Wales: time series analysis
  8. 2026-09-07srcPharmacokinetic drug interactions of synthetic opiate analgesics
  9. 2026-09-07srcUse of analgesics in intentional drug overdose presentations to hospital before and after the withdrawal of distalgesic from the Irish market
  10. 2026-09-07srcSix-year follow-up of impact of co-proxamol withdrawal in England and Wales on prescribing and deaths: time-series study
  11. 2026-09-07srcOpioids for chronic noncancer pain: a meta-analysis of effectiveness and side effects
  12. 2026-09-07srcDextropropoxyphene effects on QTc-interval prolongation: Frequency and characteristics in relation to plasma levels
  13. 2026-09-07srcSuicides may be overreported and accidents underreported among fatalities due to dextropropoxyphene
  14. 2026-09-07srcNorpropoxyphene-induced cardiotoxicity is associated with changes in ion-selectivity and gating of HERG currents
  15. 2026-09-07srcMiddle-aged men--a risk category regarding fatal poisoning due to dextropropoxyphene and alcohol in combination
  16. 2026-09-07srcPropoxyphene bioavailability: an evaluation of ten products
  17. 2026-09-07srcInteraction of alcohol and drugs in fatal poisonings
  18. 2026-09-07srcPropoxyphene and norpropoxyphene: influence of diet and fluid on plasma levels
  19. 2026-09-07srcTherapeutic usefulness of propoxyphene napsylate in narcotic addiction
  20. 2026-09-07srcA multicentre study of coproxamol poisoning suicides based on coroners' records in England
  21. 2026-09-07srcCYP3A4 mediates dextropropoxyphene N-demethylation to nordextropropoxyphene: human in vitro and in vivo studies and lack of CYP2D6 involvement
  22. 2026-09-07srcAcute pain management pharmacology for the patient with concurrent renal or hepatic disease
  23. 2026-09-07srcMonoamine oxidase inhibitors, opioid analgesics and serotonin toxicity.
  24. 2026-09-07srcRelation of postmortem blood alcohol and drug concentrations in fatal poisonings involving amitriptyline, propoxyphene and promazine
  25. 2026-09-07srcProfound metoprolol-induced bradycardia precipitated by acetaminophen-propoxyphene
  26. 2026-09-07srcPropoxyphene (dextropropoxyphene): a critical review of a weak opioid analgesic that should remain in antiquity
  27. 2026-09-07srcCYP3A5 but not CYP2D6 polymorphism contributes significantly to the variability in dextropropoxyphene disposition
  28. 2026-09-07srcMarked QRS complex abnormalities and sodium channel blockade by propoxyphene reversed with lidocaine
  29. 2026-09-07srcCarbamazepine drug interactions
  30. 2026-09-07srcPropoxyphene napsylate compared to methadone for opiate dependence
  31. 2026-09-07srcd-Propoxyphene acts differently from morphine on opioid receptor-effector mechanisms
  32. 2026-09-07srcDextropropoxyphene overdosage. Pharmacological considerations and clinical management
  33. 2026-09-07srcDextropropoxyphene deaths: coroner's report
  34. 2026-09-07srcPharmacokinetics of dextropropoxyphene and nordextropropoxyphene in elderly hospital patients after single and multiple doses of distalgesic
  35. 2026-09-07srcPropoxyphene dependence: an update
  36. 2026-09-07srcSimultaneous determination of dextromoramide, propoxyphene and norpropoxyphene in necropsic whole blood by liquid chromatography
  37. 2026-09-07srcA novel approach to the pharmacology of analgesics
  38. 2026-09-07srcSystematic overview of co-proxamol to assess analgesic effects of addition of dextropropoxyphene to paracetamol
  39. 2026-09-07srcDextropropoxyphene legal status and 2010 US withdrawal
  40. 2026-09-07srcPropoxyphene synthesis history - Pohland and Sullivan 1953
  41. 2026-09-04issueIssued emergency
  42. 2026-09-04issueIssued info_card
  43. 2026-09-04issueIssued notice
  44. 2026-06-04proposal27 value proposals approved togetherone review action inferred from a shared reviewer and instant — the graph records one activity per proposal
  45. 2026-06-04publicationPublication — backfill
  46. 2026-05-09revisionRevision 1
  47. 2026-05-09genGeneration — pipeline-v5 · with 2 morepipeline-v5
  48. 2026-05-09rungeneration run

The same entries, as forms: six forms.