In an emergency
Poison Control (US)1-800-222-1222Fireside Project62-FIRESIDE
Overdose signs
- Deliriants are genuinely dangerous — treat any strong reaction as a medical emergency.
- True delirium — confused, disoriented, doesn't know what's real or recognize people/danger
- Vivid, frightening hallucinations; agitation or aggression
- Hot, flushed, dry skin and high body temperature
- Dilated pupils; blurred vision
- Fast heartbeat; inability to urinate
- Seizures; unconsciousness
First response
- Call emergency services — deliriant poisoning (especially datura / belladonna) can be life-threatening
- Keep them physically safe — they may not know what they're doing and can badly injure themselves; remove hazards and stay with them
- Do not leave them alone; do not try to reason them out of it — they are delirious
- If overheating, cool the body
- Recovery position if drowsy, vomiting, or unconscious; be ready for rescue breaths / CPR
For the medical team
Tell the dispatcher a deliriant / anticholinergic is suspected (e.g. datura, belladonna, or a high dose of diphenhydramine), and what/how much if known. These cause dangerous delirium and overheating; datura/belladonna potency is wildly unpredictable and can be fatal. Hospitals may use physostigmine for severe anticholinergic poisoning — it is not something to give outside medical care.
Resolution
Deliriant effects are long (many hours to more than a day) and the person is not safe or in control throughout. The main dangers are self-injury during delirium, overheating, and — for potent anticholinergics like datura — cardiac and central-nervous-system toxicity. Medical monitoring is often needed.