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1Provenance card

the boundary, as counts

Sources

3824 with DOI

9 strong · 25 moderate · 4 weak

Compilations

12026-05-13T08:52:52.271Z

pipeline-v5 · prompt hash not recorded — run predates 2026-09

Decisions

20last ruled 2026-06-04

0 awaiting a ruling

Issued documents

42026-10-19T20:31:13.284Z

notice · info card · emergency

Searches

200 with no results

queries and counts on the build

Claims checked

1436 supported

6 supported · 137 not

Correspondence

0received

consent field ships in Phase 4

Edges

375

derivations recorded for this entity

Complete over 38 sources, 1 compilation, and 20 decisions.Not here: the private journal (never).Working material — drafts, discards, unsupported claims — is listed below and readable on the working page.Cite: psychedex.org/substances/cocoa/archive

Timeline

what happened, newest first — claims, searches and artifacts stay inside Build

  1. 2026-10-19issueIssued info_card
  2. 2026-09-07srcEffect of cocoa on blood pressure.
  3. 2026-09-07srcEffects of cocoa extract and a multivitamin on cognitive function: A randomized clinical trial (COSMOS-Mind).
  4. 2026-09-07srcEffect of the solid state fermentation of cocoa shell on the secondary metabolites, antioxidant activity, and fatty acids.
  5. 2026-09-07srcCaffeine intake during pregnancy and adverse birth outcomes: a systematic review and dose-response meta-analysis.
  6. 2026-09-07srcImpact of Coffee and Cacao Purine Metabolites on Neuroplasticity and Neurodegenerative Disease
  7. 2026-09-07srcDark chocolate, heavy metals, and neurodevelopment in children.
  8. 2026-09-07srcIdentification and quantification of free and bound phenolic compounds in high-molecular weight melanoidin fractions derived from two different types of cocoa beans.
  9. 2026-09-07srcFlavan-3-ol-methylxanthine interactions: Modulation of flavan-3-ol bioavailability in volunteers with a functional colon and an ileostomy
  10. 2026-09-07srcRevisiting the bioavailability of flavan-3-ols in humans: A systematic review and comprehensive data analysis.
  11. 2026-09-07srcCocoa-laden cadmium threatens human health and cacao economy: A critical view.
  12. 2026-09-07srcEffects of high flavanol dark chocolate on cardiovascular function and platelet aggregation
  13. 2026-09-07srcThe cardiovascular benefits of dark chocolate.
  14. 2026-09-07srcPerspective on Cadmium and Lead in Cocoa and Chocolate.
  15. 2026-09-07srcSimulated gastrointestinal digestion of cocoa powder (INFOGEST): methylxanthine bioaccessibility and antioxidant properties.
  16. 2026-09-07srcPre-clinical and cellular toxicity evaluation of 7-methylxanthine.
  17. 2026-09-07srcEffect of cocoa flavanol supplementation for the prevention of cardiovascular disease events: COSMOS randomized clinical trial.
  18. 2026-09-07srcThe History of Cacao and Its Diseases in the Americas.
  19. 2026-09-07srcChromatographic Profiling of Artisanal Chocolates: Volatile Composition and Methylxanthines as Markers of Cocoa Content.
  20. 2026-09-07srcClinical benefit and preservation of flavonols in dark chocolate manufacturing.
  21. 2026-09-07srcThe relevance of theobromine for the beneficial effects of cocoa consumption.
  22. 2026-09-07srcProfile of Bioactive Components of Cocoa (Theobroma cacao L.) By-Products from Ecuador.
  23. 2026-09-07srcTheobromine Targets Adenosine Receptors to Control Hippocampal Neuronal Function and Damage
  24. 2026-09-07srcStructure-Bioactivity Relationships of Methylxanthines: Trying to Make Sense of All the Promises and the Drawbacks.
  25. 2026-09-07srcSub-Chronic Consumption of Dark Chocolate Enhances Cognitive Function and Releases Nerve Growth Factors: A Parallel-Group Randomized Trial
  26. 2026-09-07srcHPLC method for the quantification of procyanidins in cocoa and chocolate samples.
  27. 2026-09-07srcCannabinoid mimics in chocolate utilized as an argument in court.
  28. 2026-09-07srcCaffeine as a model drug of dependence: recent developments in understanding caffeine withdrawal, the caffeine dependence syndrome, and caffeine negative reinforcement.
  29. 2026-09-07srcMarijuana and chocolate.
  30. 2026-09-07srcCacao usage by the earliest Maya civilization.
  31. 2026-09-07srcCacao domestication II: progenitor germplasm of the Trinitario cacao cultivar.
  32. 2026-09-07srcTheobromine inhibits sensory nerve activation and cough
  33. 2026-09-07srcCaffeine and related purine alkaloids: biosynthesis, catabolism, function and genetic engineering.
  34. 2026-09-07srcEvaluation of the teratogenic potential of cocoa powder and theobromine in New Zealand White rabbits
  35. 2026-09-07srcHuman coffee drinking: reinforcing and physical dependence producing effects of caffeine.
  36. 2026-09-07srcSevere hypernatremia in a dog following activated charcoal treatment for chocolate ingestion.
  37. 2026-09-07srcBrain cannabinoids in chocolate.
  38. 2026-09-07srcTheobroma cacao (L.) — First described by Linnaeus, Species Plantarum, 1753; European Introduction timeline
  39. 2026-09-07srcTheobroma cacao — Plants of the World Online
  40. 2026-09-04issueIssued emergency
  41. 2026-09-04issueIssued info_card
  42. 2026-09-04issueIssued notice
  43. 2026-06-04proposal15 value proposals approved togetherone review action inferred from a shared reviewer and instant — the graph records one activity per proposal
  44. 2026-06-04publicationPublication — backfill
  45. 2026-05-13revisionRevision 2
  46. 2026-05-13genGeneration — pipeline-v5 · with 2 morepipeline-v5
  47. 2026-05-13rungeneration run
  48. 2026-03-17importImported from Curiosity v1
  49. 2026-03-17publicationPublication — backfill
  50. 2026-03-17revisionRevision 1

The same entries, as forms: six forms.