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Coca Facts

Stimulant; Substituted tropane; Dopamine reuptake inhibitor

Dose and duration

No dose or duration recorded for any route.

Body and dependence

Acute toxicity
High
Chronic toxicity
Critical
Physical dependence
Low
Psychological dependence
High
Withdrawal
Moderate
Compulsive redosing
High

Tolerance

Builds
Rapid
Fully resets after
Not recorded
Carries over to
amphetamines

Effectslikely at a common dose

Body
Stimulation; Vasoconstriction; Wakefulness; +17 possible, including Heart rate perception changes, Insomnia, Muscle tension
Thinking
none likely · 11 possible, including Compulsive redosing urge
Feeling
Euphoria; +2 possible, including Anxiety
Self
none likely · 7 possible, including Craving, Ego inflation
Awareness
Sustained attention (vicara)

Who shouldn't take it

Absolute
Pre-existing cardiac conditions; Concurrent beta-blocker therapy; Uncontrolled hypertension; Hyperthyroidism / pheochromocytoma; Pregnancy; Prenatal exposure
Relative
Schizophrenia spectrum / psychosis vulnerability; Liver disease; Concurrent MAOI use; Concurrent tricyclic antidepressant use

Combinations61 recorded

Lethal (2)
Ibogaine; Opioids
Dangerous (39)
Amphetamines; Benzodiazepines, Barbiturates; Ephedrine, Pseudoephedrine; Local anesthetics; MAOIs; MDMA, Amphetamines; MDMA, MDA; NDRIs (Wellbutrin); Nicotine; NRIs; SSRIs; Stimulants; 5-HTP, Tryptophan; Alpha-2 adrenergic receptor antagonist; Anticholinergics; Antihistamines; Antipsychotics; Atypical antipsychotics; Buspirone; Caffeine; Clonidine, Guanfacine; Dopamine agonists; DXM; GHB, Baclofen; and 15 more, see full page
Caution (17)
See full page: psychedex.org/substances/coca
Not graded (3)
Not listed never means safe.

Seek help immediately if

No emergency profile is recorded for this substance. Not recorded never means no risk.

988 Suicide & Crisis LifelineFireside Project: 62-FIRESIDE

psychedex.org/substances/coca · Version r2 · Not medical adviceValues as of
On the printout