Clonidine Facts
Depressant;
Dose and durationby route · individual sensitivity varies
Oral(μg)
Threshold< 25 μgLight50 – 75 μgCommon75 – 100 μgStrong100 – 300 μgHeavy300+ μg
Starts in 15 – 45 minLasts 6 – 8 hours
Body and dependence
- Acute toxicity
- Moderate
- Chronic toxicity
- Moderate
- Physical dependence
- None
- Psychological dependence
- None
- Withdrawal
- Not assessed
- Compulsive redosing
- Not assessed
Tolerance
Not recorded.
Effectslikely at a common dose
- Perception
- none likely · 1 possible
- Body
- none likely · 5 possible, including Dizziness
- Thinking
- none likely · 4 possible
- Feeling
- none likely · 2 possible
Who shouldn't take it
None recorded. Not listed never means safe to take.
Combinations60 recorded
Dangerous (22)
Alpha-2 adrenergic receptor antagonist;
Caution (27)
See full page: psychedex.org/substances/clonidine
Not graded (11)
Not listed never means safe.
Seek help immediately if
No emergency profile is recorded for this substance. Not recorded never means no risk.
988 Suicide & Crisis LifelineFireside Project: 62-FIRESIDE
psychedex.org/substances/clonidine · Version r1 · Not medical adviceValues as of