Bufotenin
5-hydroxy-N,N-dimethyltryptamine
1Provenance card
the boundary, as counts
Sources
3111 with DOI
2 strong · 24 moderate · 5 weak
Compilations
12026-04-26T17:33:52.792Z
pipeline-v5 · prompt hash not recorded — run predates 2026-09
Decisions
29last ruled 2026-06-04
0 awaiting a ruling
Issued documents
62026-10-19T20:30:54.530Z
notice · info card · emergency
Searches
182 with no results
queries and counts on the build
Claims checked
7263 supported
63 supported · 9 not
Correspondence
0received
consent field ships in Phase 4
Edges
239
derivations recorded for this entity
Complete over 31 sources, 1 compilation, and 29 decisions.Not here: the private journal (never).Working material — drafts, discards, unsupported claims — is listed below and readable on the working page.Cite: psychedex.org/substances/bufotenin/archive
Timeline
what happened, newest first — claims, searches and artifacts stay inside Build
- 2026-10-19issueIssued emergency
- 2026-10-19issueIssued info_card
- 2026-10-19issueIssued notice
- 2026-09-24srcCardiovascular effects of bufotenin on human 5-HT4 serotonin receptors in cardiac preparations of transgenic mice and in human atrial preparations.
- 2026-09-24srcSerotonin syndrome and pain medication: What is relevant for practice?
- 2026-09-24srcSpectroscopic behavior of bufotenine and bufotenine N-oxide: Solvent and pH effects and interaction with biomembrane models.
- 2026-09-24srcAnti-inflammatory and analgesic actions of bufotenine through inhibiting lipid metabolism pathway.
- 2026-09-24srcInteraction of psychedelic tryptamine derivatives with a lipid bilayer
- 2026-09-24srcDesmodeleganine, a new alkaloid from the leaves of Desmodium elegans as a potential monoamine oxidase inhibitor.
- 2026-09-24srcA cane toad (Rhinella marina) N-methyltransferase converts primary indolethylamines to tertiary psychedelic amines.
- 2026-09-24srcBufotenine and its derivatives: synthesis, analgesic effects identification and computational target prediction.
- 2026-09-24srcSerotonin 1A Receptors Modulate Serotonin 2A Receptor-Mediated Behavioral Effects of 5-Methoxy-N,N-dimethyltryptamine Analogs in Mice
- 2026-09-24srcRapid, open-source, and automated quantification of the head twitch response in C57BL/6J mice using DeepLabCut and Simple Behavioral Analysis.
- 2026-09-24srcElevated Endogenous Psychedelic Bufotenine in the Urine of Patients Diagnosed With a Mental Illness: A Systematic Review.
- 2026-09-24srcBufotenine: toward an understanding of possible psychoactive mechanisms.
- 2026-09-24srcRNA-editing of the 5-HT(2C) receptor alters agonist-receptor-effector coupling specificity.
- 2026-09-24srcMolecular basis of partial agonism: orientation of indoleamine ligands in the binding pocket of the human serotonin 5-HT2A receptor determines relative efficacy.
- 2026-09-24srcStimulation of rat prolactin secretion by indolealkylamine hallucinogens.
- 2026-09-24srcMonoamine oxidase inhibitors, opioid analgesics and serotonin toxicity.
- 2026-09-24srcElevated urine levels of bufotenine in patients with autistic spectrum disorders and schizophrenia.
- 2026-09-24srcBufotenine - A Hallucinogen in Ancient Snuff Powders of South America and a Drug of Abuse on the Streets of New York City.
- 2026-09-24srcUrinary excretion of 5-methoxy-N,N-dimethyltryptamine, N,N-dimethyltryptamine and their N-oxides in the rat.
- 2026-09-24srcIndolealkylamines and prolactin secretion. A structure-activity study in the central nervous system of the rat.
- 2026-09-24srcFurther studies on the mode of action of psychotomimetic drugs: antagonism of the excitatory actions of 5-hydroxytryptamine by methylated derivatives of tryptamine.
- 2026-09-24srcBufotenine esters.
- 2026-09-24srcTissue distribution, metabolism and effects of bufotenine administered to rats.
- 2026-09-24srcMapping the binding site pocket of the serotonin 5-Hydroxytryptamine2A receptor. Ser3.36(159) provides a second interaction site for the protonated amine of serotonin but not of lysergic acid diethylamide or bufotenin.
- 2026-09-24srcBufo toads and bufotenine: fact and fiction surrounding an alleged psychedelic.
- 2026-09-24srcHigh-affinity agonist binding is not sufficient for agonist efficacy at 5-hydroxytryptamine2A receptors: evidence in favor of a modified ternary complex model.
- 2026-09-24srcAltered consciousness states and endogenous psychoses: a common molecular pathway?
- 2026-09-24srcBufotenine - Britannica
- 2026-09-24srcBufotenine - Illinois Schedule I Classification (Ill. Admin. Code tit. 77 § 2070.745)
- 2026-09-24srcBufotenin - Chemical and Pharmacological Data (HandWiki)
- 2026-09-24srcBufotenin Legal Status - Erowid
- 2026-09-04issueIssued emergency
- 2026-09-04issueIssued info_card
- 2026-09-04issueIssued notice
- 2026-06-04proposal27 value proposals approved togetherone review action inferred from a shared reviewer and instant — the graph records one activity per proposal
- 2026-06-04publicationPublication — backfill
- 2026-04-26revisionRevision 1
- 2026-04-26absenceSearched ClinicalTrials.gov for "bufotenin bufotenine" — no results
- 2026-04-26absenceSearched PubMed for "Anadenanthera peregrina bufotenine alkaloid seeds cohoba" — no results
- 2026-04-26genGeneration — pipeline-v5pipeline-v5
- 2026-04-26rungeneration run
The same entries, as forms: six forms.