Skip to main content

1Provenance card

the boundary, as counts

Sources

3111 with DOI

2 strong · 24 moderate · 5 weak

Compilations

12026-04-26T17:33:52.792Z

pipeline-v5 · prompt hash not recorded — run predates 2026-09

Decisions

29last ruled 2026-06-04

0 awaiting a ruling

Issued documents

62026-10-19T20:30:54.530Z

notice · info card · emergency

Searches

182 with no results

queries and counts on the build

Claims checked

7263 supported

63 supported · 9 not

Correspondence

0received

consent field ships in Phase 4

Edges

239

derivations recorded for this entity

Complete over 31 sources, 1 compilation, and 29 decisions.Not here: the private journal (never).Working material — drafts, discards, unsupported claims — is listed below and readable on the working page.Cite: psychedex.org/substances/bufotenin/archive

Timeline

what happened, newest first — claims, searches and artifacts stay inside Build

  1. 2026-10-19issueIssued emergency
  2. 2026-10-19issueIssued info_card
  3. 2026-10-19issueIssued notice
  4. 2026-09-24srcCardiovascular effects of bufotenin on human 5-HT4 serotonin receptors in cardiac preparations of transgenic mice and in human atrial preparations.
  5. 2026-09-24srcSerotonin syndrome and pain medication: What is relevant for practice?
  6. 2026-09-24srcSpectroscopic behavior of bufotenine and bufotenine N-oxide: Solvent and pH effects and interaction with biomembrane models.
  7. 2026-09-24srcAnti-inflammatory and analgesic actions of bufotenine through inhibiting lipid metabolism pathway.
  8. 2026-09-24srcInteraction of psychedelic tryptamine derivatives with a lipid bilayer
  9. 2026-09-24srcDesmodeleganine, a new alkaloid from the leaves of Desmodium elegans as a potential monoamine oxidase inhibitor.
  10. 2026-09-24srcA cane toad (Rhinella marina) N-methyltransferase converts primary indolethylamines to tertiary psychedelic amines.
  11. 2026-09-24srcBufotenine and its derivatives: synthesis, analgesic effects identification and computational target prediction.
  12. 2026-09-24srcSerotonin 1A Receptors Modulate Serotonin 2A Receptor-Mediated Behavioral Effects of 5-Methoxy-N,N-dimethyltryptamine Analogs in Mice
  13. 2026-09-24srcRapid, open-source, and automated quantification of the head twitch response in C57BL/6J mice using DeepLabCut and Simple Behavioral Analysis.
  14. 2026-09-24srcElevated Endogenous Psychedelic Bufotenine in the Urine of Patients Diagnosed With a Mental Illness: A Systematic Review.
  15. 2026-09-24srcBufotenine: toward an understanding of possible psychoactive mechanisms.
  16. 2026-09-24srcRNA-editing of the 5-HT(2C) receptor alters agonist-receptor-effector coupling specificity.
  17. 2026-09-24srcMolecular basis of partial agonism: orientation of indoleamine ligands in the binding pocket of the human serotonin 5-HT2A receptor determines relative efficacy.
  18. 2026-09-24srcStimulation of rat prolactin secretion by indolealkylamine hallucinogens.
  19. 2026-09-24srcMonoamine oxidase inhibitors, opioid analgesics and serotonin toxicity.
  20. 2026-09-24srcElevated urine levels of bufotenine in patients with autistic spectrum disorders and schizophrenia.
  21. 2026-09-24srcBufotenine - A Hallucinogen in Ancient Snuff Powders of South America and a Drug of Abuse on the Streets of New York City.
  22. 2026-09-24srcUrinary excretion of 5-methoxy-N,N-dimethyltryptamine, N,N-dimethyltryptamine and their N-oxides in the rat.
  23. 2026-09-24srcIndolealkylamines and prolactin secretion. A structure-activity study in the central nervous system of the rat.
  24. 2026-09-24srcFurther studies on the mode of action of psychotomimetic drugs: antagonism of the excitatory actions of 5-hydroxytryptamine by methylated derivatives of tryptamine.
  25. 2026-09-24srcBufotenine esters.
  26. 2026-09-24srcTissue distribution, metabolism and effects of bufotenine administered to rats.
  27. 2026-09-24srcMapping the binding site pocket of the serotonin 5-Hydroxytryptamine2A receptor. Ser3.36(159) provides a second interaction site for the protonated amine of serotonin but not of lysergic acid diethylamide or bufotenin.
  28. 2026-09-24srcBufo toads and bufotenine: fact and fiction surrounding an alleged psychedelic.
  29. 2026-09-24srcHigh-affinity agonist binding is not sufficient for agonist efficacy at 5-hydroxytryptamine2A receptors: evidence in favor of a modified ternary complex model.
  30. 2026-09-24srcAltered consciousness states and endogenous psychoses: a common molecular pathway?
  31. 2026-09-24srcBufotenine - Britannica
  32. 2026-09-24srcBufotenine - Illinois Schedule I Classification (Ill. Admin. Code tit. 77 § 2070.745)
  33. 2026-09-24srcBufotenin - Chemical and Pharmacological Data (HandWiki)
  34. 2026-09-24srcBufotenin Legal Status - Erowid
  35. 2026-09-04issueIssued emergency
  36. 2026-09-04issueIssued info_card
  37. 2026-09-04issueIssued notice
  38. 2026-06-04proposal27 value proposals approved togetherone review action inferred from a shared reviewer and instant — the graph records one activity per proposal
  39. 2026-06-04publicationPublication — backfill
  40. 2026-04-26revisionRevision 1
  41. 2026-04-26absenceSearched ClinicalTrials.gov for "bufotenin bufotenine" — no results
  42. 2026-04-26absenceSearched PubMed for "Anadenanthera peregrina bufotenine alkaloid seeds cohoba" — no results
  43. 2026-04-26genGeneration — pipeline-v5pipeline-v5
  44. 2026-04-26rungeneration run

The same entries, as forms: six forms.