Adrafinil
1Provenance card
the boundary, as counts
Sources
3925 with DOI
7 strong · 25 moderate · 7 weak
Compilations
22026-05-12T21:56:24.090Z
pipeline-v5 · prompt hash not recorded — run predates 2026-09
Decisions
30last ruled 2026-06-04
0 awaiting a ruling
Issued documents
42026-10-19T20:30:26.651Z
notice · info card · emergency
Searches
00 with no results
queries and counts on the build
Claims checked
8667 supported
67 supported · 19 not
Correspondence
0received
consent field ships in Phase 4
Edges
254
derivations recorded for this entity
Complete over 39 sources, 2 compilations, and 30 decisions.Not here: the private journal (never).Working material — drafts, discards, unsupported claims — is listed below and readable on the working page.Cite: psychedex.org/substances/adrafinil/archive
Timeline
what happened, newest first — claims, searches and artifacts stay inside Build
- 2026-10-19issueIssued info_card
- 2026-09-07srcEffects of modafinil on dopamine and dopamine transporters in the male human brain: clinical implications.
- 2026-09-07srcEnantioselective separation and determination of adrafinil and modafinil on Chiralcel OJ-H column in rat serum and urine using solid-phase extraction followed by HPLC.
- 2026-09-07srcDevelopment of a validated LC method for enantiomeric separation and determination of adrafinil and its related substances on a Chiralcel OJ-H column.
- 2026-09-07srcOutsmarted by nootropics? An investigation into the thermal degradation of modafinil, modafinic acid, adrafinil, CRL-40,940 and CRL-40,941 in the GC injector.
- 2026-09-07srcLC-MS of novel narcoepileptics and related substances.
- 2026-09-07srcAdrafinil-induced orofacial dyskinesia.
- 2026-09-07srcDoping control analysis for adrafinil and its major metabolites in human urine.
- 2026-09-07srcModafinil, an atypical CNS stimulant?
- 2026-09-07srcA positron emission tomography study examining the dopaminergic activity of armodafinil in adults using [11C]altropane and [11C]raclopride.
- 2026-09-07srcCardiovascular stimulant actions of bupropion in comparison to cocaine in the rat.
- 2026-09-07srcModafinil for cognitive neuroenhancement in healthy non-sleep-deprived subjects: A systematic review.
- 2026-09-07srcHow effective are pharmaceuticals for cognitive enhancement in healthy adults? A series of meta-analyses of cognitive performance during acute administration of modafinil, methylphenidate and D-amphetamine
- 2026-09-07srcLC-ESI-MS determination and pharmacokinetics of adrafinil in rats.
- 2026-09-07srcElectrophysiological and amperometric evidence that modafinil blocks the dopamine uptake transporter to induce behavioral activation.
- 2026-09-07srcModafinil: its discovery, the early European and North American experience in the treatment of narcolepsy and idiopathic hypersomnia, and its subsequent use in other medical conditions.
- 2026-09-07srcPharmacokinetic and pharmacodynamic of the cognitive enhancer modafinil: Relevant clinical and forensic aspects.
- 2026-09-07srcDevelopment and Validation of an Analytical Method to Identify and Quantitate Novel Modafinil Analogs in Products Marketed as Dietary Supplements.
- 2026-09-07srcIdentification of adrafinil and its main metabolite modafinil in human hair. Self-administration study and interpretation of an authentic case.
- 2026-09-07srcSleep medicine, sleep research, and sleep education: a whole life devoted to sleep.
- 2026-09-07srcAdrafinil: A Novel Vigilance Promoting Agent
- 2026-09-07srcThe role of eugeroics in the treatment of affective disorders.
- 2026-09-07srcFunctional neuroanatomy of dopaminergic arousal systems: implications for the wake-promoting effect of psychostimulants, with particular reference to modafinil.
- 2026-09-07srcThe Psychonauts' World of Cognitive Enhancers
- 2026-09-07srcModafinil augmentation therapy in unipolar and bipolar depression: a systematic review and meta-analysis of randomized controlled trials.
- 2026-09-07srcA novel study of screening and confirmation of modafinil, adrafinil and their metabolite modafinilic acid under EI-GC-MS and ESI-LC-MS-MS ionization.
- 2026-09-07srcIn vitro inhibition and induction of human hepatic cytochrome P450 enzymes by modafinil.
- 2026-09-07srcAdrafinil: effects on behavior and cognition in aged canines.
- 2026-09-07srcIncreased dopaminergic transmission mediates the wake-promoting effects of CNS stimulants.
- 2026-09-07srcEffect of modafinil on the pharmacokinetics of ethinyl estradiol and triazolam in healthy volunteers.
- 2026-09-07srcClinical pharmacokinetic profile of modafinil.
- 2026-09-07srcWhat keeps us awake: the neuropharmacology of stimulants and wakefulness-promoting medications.
- 2026-09-07srcInfluence of alpha stimulants and beta blockers on yohimbine toxicity.
- 2026-09-07srcSingle-dose pharmacokinetics of modafinil and methylphenidate given alone or in combination in healthy male volunteers.
- 2026-09-07srcAdrafinil - Wikipedia
- 2026-09-07srcPubChem Compound: Adrafinil (CID 3033226)
- 2026-09-07srcNCATS Inxight Drugs: Adrafinil (BI81Z4542G)
- 2026-09-07srcChemicalBook: Adrafinil (CAS 63547-13-7) Physical Properties
- 2026-09-07srcWADA Prohibited List 2025 - S6 Stimulants category
- 2026-09-07srcModafinil/Armodafinil - LiverTox: Clinical and Research Information on Drug-Induced Liver Injury
- 2026-09-04issueIssued emergency
- 2026-09-04issueIssued info_card
- 2026-09-04issueIssued notice
- 2026-06-04proposal28 value proposals approved togetherone review action inferred from a shared reviewer and instant — the graph records one activity per proposal
- 2026-06-04publicationPublication — backfill
- 2026-05-12revisionRevision 1
- 2026-05-12genGeneration — pipeline-v5 · with 3 morepipeline-v5
- 2026-05-12rungeneration run
- 2026-05-11rungeneration run
The same entries, as forms: six forms.