A-PVP
α-pyrrolidinopentiophenone
1Provenance card
the boundary, as counts
Sources
3836 with DOI
0 strong · 35 moderate · 3 weak
Compilations
12026-04-26T00:41:36.699Z
pipeline-v5 · prompt hash not recorded — run predates 2026-09
Decisions
51last ruled 2026-06-04
0 awaiting a ruling
Issued documents
42026-10-19T20:30:23.507Z
notice · info card · emergency
Searches
181 with no results
queries and counts on the build
Claims checked
9380 supported
80 supported · 13 not
Correspondence
0received
consent field ships in Phase 4
Edges
306
derivations recorded for this entity
Complete over 38 sources, 1 compilation, and 51 decisions.Not here: the private journal (never).Working material — drafts, discards, unsupported claims — is listed below and readable on the working page.Cite: psychedex.org/substances/a-pvp/archive
Timeline
what happened, newest first — claims, searches and artifacts stay inside Build
- 2026-10-19issueIssued info_card
- 2026-09-24srcThe prevalence of new psychoactive substances in biological material - a three-year review of casework in Poland.
- 2026-09-24srcCharacterization of neurotransmitter inhibition for seven cathinones by a proprietary fluorescent dye method.
- 2026-09-24srcNeuropharmacology of 3,4-Methylenedioxypyrovalerone (MDPV), Its Metabolites, and Related Analogs
- 2026-09-24srcSelf-administration and behavioral economics of second-generation synthetic cathinones in male rats.
- 2026-09-24srcEffects of the new generation α-pyrrolidinophenones on spontaneous locomotor activities in mice, and on extracellular dopamine and serotonin levels in the mouse striatum.
- 2026-09-24srcA review of synthetic cathinones emerging in recent years (2019–2022).
- 2026-09-24srcStructural and functional perspectives on interactions between synthetic cathinones and monoamine transporters.
- 2026-09-24srcPsychoactive 'bath salts' intoxication with methylenedioxypyrovalerone
- 2026-09-24srcSynthetic cathinone self-administration in female rats modulates neurotransmitter levels in addiction-related brain regions.
- 2026-09-24srcEffects of α-pyrrolidino-phenone cathinone stimulants on locomotor behavior in female rats.
- 2026-09-24srcFindings of synthetic cathinones in post-mortem toxicology.
- 2026-09-24srcSynthetic cathinones (bath salts)
- 2026-09-24srcNew psychoactive versus conventional stimulants - a ten-year review of casework in Hungary.
- 2026-09-24srcSex differences in inflammatory cytokine levels following synthetic cathinone self-administration in rats.
- 2026-09-24srcRelative reinforcing effects of second-generation synthetic cathinones: Acquisition of self-administration and fixed ratio dose-response curves in rats.
- 2026-09-24srcNeuroadaptive changes and behavioral effects after a sensitization regime of MDPV.
- 2026-09-24srcRole of amino terminal substitutions in the pharmacological, rewarding and psychostimulant profiles of novel synthetic cathinones.
- 2026-09-24srcSex differences in α-pyrrolidinopentiophenone (α-PVP)-induced taste avoidance, place preference, hyperthermia and locomotor activity in rats.
- 2026-09-24srcEthanol pre-exposure differentially impacts the rewarding and aversive effects of α-pyrrolidinopentiophenone (α-PVP).
- 2026-09-24srcConditioned place preference with low dose mixtures of α-pyrrolidinopentiophenone (α-PVP) and 3,4-methylenedioxypyrovalerone (MDPV) in male and female Sprague-Dawley rats.
- 2026-09-24srcAlpha pyrrolidinovalerophenone (α-PVP) administration impairs spatial learning and memory in rats through brain mitochondrial dysfunction.
- 2026-09-24srcMeasuring inhibition of monoamine reuptake transporters by new psychoactive substances (NPS) in real-time using a high-throughput, fluorescence-based assay.
- 2026-09-24srcStructural Modification of the Designer Stimulant α-Pyrrolidinovalerophenone (α-PVP) Influences Potency at Dopamine Transporters.
- 2026-09-24srcThe abuse-related effects of pyrrolidine-containing cathinones are related to their potency and selectivity to inhibit the dopamine transporter.
- 2026-09-24srcToxicological Analysis of Cases of Mixed Poisonings with Synthetic Cathinones and Other Drugs of Abuse.
- 2026-09-24srcTesting for designer stimulants: metabolic profiles of 16 synthetic cathinones excreted free in human urine.
- 2026-09-24srcCocaine-like discriminative stimulus effects of alpha-pyrrolidinovalerophenone, methcathinone and their 3,4-methylenedioxy or 4-methyl analogs in rhesus monkeys.
- 2026-09-24srcStereoselective neurochemical, behavioral, and cardiovascular effects of α-pyrrolidinovalerophenone enantiomers in male rats.
- 2026-09-24srcEarly and Mid-Term Disposition of α-PVP and its unknown Metabolites in Urine and Oral Fluid Through a Multi-Analytical Hyphenated Approach Following a Single Non-Controlled Administration to Healthy Volunteers.
- 2026-09-24srcRisk factors for the development of psychotic disorders associated with synthetic cathinones usage.
- 2026-09-24srcPharmacokinetics of α-Pyrrolidinovalerophenone in Male Rats with and without Vaccination with an α-Pyrrolidinovalerophenone Vaccine.
- 2026-09-24srcAlpha-PVP induces the rewarding effect via activating dopaminergic neuron.
- 2026-09-24srcHazard Characterization of Synthetic Cathinones Using Viability, Monoamine Reuptake, and Neuronal Activity Assays
- 2026-09-24srcAcute pharmacological effects of α-PVP in humans: a naturalistic observational study.
- 2026-09-24srcMolecular Toxicological Mechanisms of Synthetic Cathinones on C2C12 Myoblasts.
- 2026-09-24srcFlakka: New Dangerous Synthetic Cathinone on the Drug Scene.
- 2026-09-24srcα-PVP placed in Schedule I (US DEA)
- 2026-09-24srcEU Council Decision on control measures for α-PVP
- 2026-09-04issueIssued emergency
- 2026-09-04issueIssued info_card
- 2026-09-04issueIssued notice
- 2026-06-04proposal49 value proposals approved togetherone review action inferred from a shared reviewer and instant — the graph records one activity per proposal
- 2026-06-04publicationPublication — backfill
- 2026-04-26revisionRevision 1
- 2026-04-26absenceSearched ClinicalTrials.gov for "alpha-PVP pyrrolidinopentiophenone stimulant" — no results
- 2026-04-26genGeneration — pipeline-v5 · with 2 morepipeline-v5
- 2026-04-26rungeneration run
The same entries, as forms: six forms.