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1Provenance card

the boundary, as counts

Sources

2115 with DOI

2 strong · 10 moderate · 9 weak

Compilations

12026-05-11T16:47:05.123Z

pipeline-v5 · prompt hash not recorded — run predates 2026-09

Decisions

34last ruled 2026-06-04

0 awaiting a ruling

Issued documents

42026-10-19T20:30:06.275Z

notice · info card · emergency

Searches

243 with no results

queries and counts on the build

Claims checked

7952 supported

52 supported · 27 not

Correspondence

0received

consent field ships in Phase 4

Edges

250

derivations recorded for this entity

Complete over 21 sources, 1 compilation, and 34 decisions.Not here: the private journal (never).Working material — drafts, discards, unsupported claims — is listed below and readable on the working page.Cite: psychedex.org/substances/4f-eph/archive

Timeline

what happened, newest first — claims, searches and artifacts stay inside Build

  1. 2026-10-19issueIssued info_card
  2. 2026-09-07srcAnalysis of six 'neuro-enhancing' phenidate analogs
  3. 2026-09-07srcAnalytical characterization and pharmacological evaluation of the new psychoactive substance 4-fluoromethylphenidate (4F-MPH) and differentiation between the (±)-threo and (±)-erythro diastereomers
  4. 2026-09-07srcEthylphenidate as a selective dopaminergic agonist and methylphenidate-ethanol transesterification biomarker.
  5. 2026-09-07srcDesigner drugs: mechanism of action and adverse effects
  6. 2026-09-07srcDiscriminative stimulus, rewarding, and reinforcing effects of 4-Fluoroethylphenidate in rodents
  7. 2026-09-07srcOverdose of drugs for attention-deficit hyperactivity disorder: clinical presentation, mechanisms of toxicity, and management.
  8. 2026-09-07srcTramadol: Understanding the Risk of Serotonin Syndrome and Seizures
  9. 2026-09-07srcPharmacological profile of methylphenidate-based designer drugs
  10. 2026-09-07srcPharmacokinetic and pharmacodynamic effects of methylphenidate and MDMA administered alone or in combination
  11. 2026-09-07srcAnalytically Confirmed Intoxication by 4-Fluoromethylphenidate, an Analog of Methylphenidate
  12. 2026-09-07src4-Fluoromethylphenidate: Fatal Intoxication Involving a Previously Unreported Novel Psychoactive Substance in the USA
  13. 2026-09-07srcDifferential influences of ethanol on early exposure to racemic methylphenidate compared with dexmethylphenidate in humans
  14. 2026-09-07srcFirst Death Involving 4-Fluoroethylphenidate (4F-EPH): Case Report, User Experiences, and Review of the Related Literature
  15. 2026-09-07srcUse of cognitive enhancers: methylphenidate and analogs
  16. 2026-09-07srcNovel psychoactive substances (designer drugs): overview and pharmacology of modulators of monoamine signaling
  17. 2026-09-07srcUK Misuse of Drugs Act 1971 (Amendment) Order 2017 — 4F-EPH Class B scheduling
  18. 2026-09-07srcBluelight 4F-EPH review thread (user reports, 2019)
  19. 2026-09-07src4F-EPH PsychonautWiki — dosage, duration, effects overview
  20. 2026-09-07src4F-EPH first detection: France and UK, March 2016 (EMCDDA/EDND records)
  21. 2026-09-07src4F-EPH SMILES and CAS number — 2160555-59-7
  22. 2026-09-07srcEthylphenidate monoamine transporter binding affinities (d-EPH: DAT IC50=27nM, NET IC50=290nM)
  23. 2026-09-04issueIssued emergency
  24. 2026-09-04issueIssued info_card
  25. 2026-09-04issueIssued notice
  26. 2026-06-04proposal32 value proposals approved togetherone review action inferred from a shared reviewer and instant — the graph records one activity per proposal
  27. 2026-06-04publicationPublication — backfill
  28. 2026-05-11revisionRevision 1
  29. 2026-05-11absenceSearched ClinicalTrials.gov for "4-fluoroethylphenidate 4F-EPH phenidate" — no results
  30. 2026-05-11absenceSearched PubChem for "4F-EPH" — no results
  31. 2026-05-11absenceSearched PubMed for "4F-EPH 4-fluoroethylphenidate stimulant" — no results
  32. 2026-05-11genGeneration — pipeline-v5 · with 3 morepipeline-v5
  33. 2026-05-11rungeneration run

The same entries, as forms: six forms.