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Psychedex

4-HO-MET

4-hydroxy-N-methyl-N-ethyltryptamine

1Provenance card

the boundary, as counts

Sources

2822 with DOI

3 strong · 17 moderate · 8 weak

Compilations

12026-04-24T08:57:47.195Z

pipeline-v5 · prompt hash not recorded — run predates 2026-09

Decisions

36last ruled 2026-06-04

0 awaiting a ruling

Issued documents

62026-10-19T20:30:00.598Z

notice · info card · emergency

Searches

234 with no results

queries and counts on the build

Claims checked

8057 supported

57 supported · 23 not

Correspondence

0received

consent field ships in Phase 4

Edges

264

derivations recorded for this entity

Complete over 28 sources, 1 compilation, and 36 decisions.Not here: the private journal (never).Working material — drafts, discards, unsupported claims — is listed below and readable on the working page.Cite: psychedex.org/substances/4-ho-met/archive

Timeline

what happened, newest first — claims, searches and artifacts stay inside Build

  1. 2026-10-19issueIssued emergency
  2. 2026-10-19issueIssued info_card
  3. 2026-10-19issueIssued notice
  4. 2026-09-24srcInvestigating the ability of the microbial model Cunninghamella elegans for the metabolism of synthetic tryptamines
  5. 2026-09-24srcPsilocin analogs II. Synthesis of 3-[2-(dialkylamino)ethyl]-, 3-[2-(N-methyl-N-alkylamino)ethyl]-, and 3-[2-(cycloalkylamino)ethyl]indol-4-ols
  6. 2026-09-24srcSerotonin toxicity of serotonergic psychedelics
  7. 2026-09-24srcPsychedelic experience dose-dependently modulated by cannabis: results of a prospective online survey
  8. 2026-09-24srcDrug-induced acute psychosis in an adolescent first-time user of 4-HO-MET
  9. 2026-09-24srcSafety and Efficacy of Monoamine Oxidase Inhibitors in Patients Who Use Psychoactive Substances
  10. 2026-09-24srcCardiovascular safety of psychedelic medicine: current status and future directions
  11. 2026-09-24srcStudy of the in vitro and in vivo metabolism of 4-HO-MET
  12. 2026-09-24srcRopinirole metabolite mimics a new psychoactive substance (4-HO-MET) in LC-MS/MS
  13. 2026-09-24srcPrevalence and associations of challenging, difficult or distressing experiences using classic psychedelics
  14. 2026-09-24srcCardiotoxic effects of [3-[2-(diethylamino)ethyl]-1H-indol-4-yl] acetate and 3-[2-[ethyl(methyl)amino]ethyl]-1H-indol-4-ol
  15. 2026-09-24srcTolerance and Cross-Tolerance among Psychedelic and Nonpsychedelic 5-HT2A Receptor Agonists in Mice
  16. 2026-09-24srcPresence of 4-Hydroxy-N-methyl-N-ethyltryptamine in Commercially Available Products
  17. 2026-09-24srcDiscriminative Stimulus Effects of Substituted Tryptamines in Rats
  18. 2026-09-24srcReceptor Binding Profiles for Tryptamine Psychedelics and Effects of 4-Propionoxy-N,N-dimethyltryptamine in Mice
  19. 2026-09-24srcCan the Intake of a Synthetic Tryptamine be Detected Only by Blood Plasma Analysis? A Clinical Toxicology Case Involving 4-HO-MET
  20. 2026-09-24srcA Fatal Case Report Resulting from the Abuse of the Designer Benzodiazepines Clonazolam and Flualprazolam in Conjunction with Dried Opium Poppy Pods
  21. 2026-09-24srcPharmacologic Activity of Substituted Tryptamines at 5-HT2A, 5-HT2C, 5-HT1A Receptors and SERT
  22. 2026-09-24srcDrug-drug interactions involving classic psychedelics: A systematic review
  23. 2026-09-24srcIndolealkylamines: biotransformations and potential drug-drug interactions
  24. 2026-09-24srcRecreational use, analysis and toxicity of tryptamines.
  25. 2026-09-24srcToxicology and Analysis of Psychoactive Tryptamines.
  26. 2026-09-24srcEffect of ring fluorination on the pharmacology of hallucinogenic tryptamines
  27. 2026-09-24srcHeaven and hell--a phenomenological study of recreational use of 4-HO-MET in Sweden
  28. 2026-09-24src4-HO-MET Legal Status
  29. 2026-09-24srcTiHKAL Entry #21: 4-HO-MET
  30. 2026-09-24src4-HO-MET Legal Status (Germany NpSG, Australia Schedule 9, Canada uncontrolled)
  31. 2026-09-24src4-HO-MET Chemical and Pharmacological Data (NCATS Inxight Drugs)
  32. 2026-09-04issueIssued emergency
  33. 2026-09-04issueIssued info_card
  34. 2026-09-04issueIssued notice
  35. 2026-06-04proposal34 value proposals approved togetherone review action inferred from a shared reviewer and instant — the graph records one activity per proposal
  36. 2026-06-04publicationPublication — backfill
  37. 2026-04-24revisionRevision 1
  38. 2026-04-24absenceSearched ClinicalTrials.gov for "4-HO-MET metocin tryptamine" — no results
  39. 2026-04-24absenceSearched PubMed for "psilocybin psilocin 5-HT2A agonist binding receptor pharmacokinetics" — no results
  40. 2026-04-24absenceSearched PubMed for "metocin tryptamine psychedelic serotonin receptor" — no results
  41. 2026-04-24absenceSearched ClinicalTrials.gov for "4-HO-MET metocin tryptamine psychedelic" — no results
  42. 2026-04-24genGeneration — pipeline-v5pipeline-v5
  43. 2026-04-24rungeneration run

The same entries, as forms: six forms.