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Psychedex

1Provenance card

the boundary, as counts

Sources

2216 with DOI

4 strong · 10 moderate · 8 weak

Compilations

12026-05-10T19:58:01.618Z

pipeline-v5 · prompt hash not recorded — run predates 2026-09

Decisions

32last ruled 2026-06-04

0 awaiting a ruling

Issued documents

42026-10-19T20:29:38.879Z

notice · info card · emergency

Searches

223 with no results

queries and counts on the build

Claims checked

7057 supported

57 supported · 13 not

Correspondence

0received

consent field ships in Phase 4

Edges

229

derivations recorded for this entity

Complete over 22 sources, 1 compilation, and 32 decisions.Not here: the private journal (never).Working material — drafts, discards, unsupported claims — is listed below and readable on the working page.Cite: psychedex.org/substances/3-ho-pce/archive

Timeline

what happened, newest first — claims, searches and artifacts stay inside Build

  1. 2026-10-19issueIssued info_card
  2. 2026-09-07srcIn vitro and in vivo metabolism and detection of 3-HO-PCP, a synthetic phencyclidine, in human samples and pooled human hepatocytes using high resolution mass spectrometry
  3. 2026-09-07srcSevere Toxicity to the New Psychoactive Substances 3-Hydroxyphencyclidine and N-Ethylhexedrone: an Analytically Confirmed Case Report
  4. 2026-09-07srcRhabdomyolysis and Acute Kidney Injury after Use of 3-Methyl-PCP: A Case Report
  5. 2026-09-07srcKetamine: A Review of Clinical Pharmacokinetics and Pharmacodynamics in Anesthesia and Pain Therapy
  6. 2026-09-07srcOn the opioid nature of phencyclidine and its 3-hydroxy derivative
  7. 2026-09-07srcCluster of acute poisonings associated with an emerging ketamine analogue, 2-oxo-PCE
  8. 2026-09-07srcFatal intoxication related to two new arylcyclohexylamine derivatives (2F-DCK and 3-MeO-PCE)
  9. 2026-09-07srcHair-based rapid UPLC-MS/MS analysis of 36 phencyclidine-type substances in forensic cases
  10. 2026-09-07srcThe pharmacology of sigma-1 receptors
  11. 2026-09-07srcExposure to oral S-ketamine is unaffected by itraconazole but greatly increased by ticlopidine
  12. 2026-09-07srcCase report of a fatal 3-hydroxyphencyclidine intoxication, including blood and hair results
  13. 2026-09-07srcKetamine and Ketamine Metabolite Pharmacology: Insights into Therapeutic Mechanisms
  14. 2026-09-07srcAttenuation of Antidepressant Effects of Ketamine by Opioid Receptor Antagonism
  15. 2026-09-07srcThe ketamine analogue methoxetamine and 3- and 4-methoxy analogues of phencyclidine are high affinity and selective ligands for the glutamate NMDA receptor
  16. 2026-09-07srcInhibition of cytochrome P450 enzymes involved in ketamine metabolism by use of liver microsomes and specific cytochrome P450 enzymes from horses, dogs, and humans
  17. 2026-09-07srcCharacterization of 3-Hydroxyeticyclidine (3-HO-PCE) Metabolism in Human Liver Microsomes and Biological Samples Using High-Resolution Mass Spectrometry
  18. 2026-09-07srcPhencyclidine receptors and N-methyl-D-aspartate antagonism: electrophysiologic data correlates with known behaviours
  19. 2026-09-07srcQuantitative autoradiographic localization of [3H]3-OH-PCP (1-(1(3-hydroxyphenyl)cyclohexyl)piperidine) binding sites in rat brain
  20. 2026-09-07srcOlanzapine and fluperlapine mimic clozapine in preventing MK-801 neurotoxicity
  21. 2026-09-07src3-HO-PCE
  22. 2026-09-07srcEticyclidine
  23. 2026-09-07srcFederal Register: Placement of 3-Methoxyphencyclidine in Schedule I (2026)
  24. 2026-09-04issueIssued emergency
  25. 2026-09-04issueIssued info_card
  26. 2026-09-04issueIssued notice
  27. 2026-06-04proposal30 value proposals approved togetherone review action inferred from a shared reviewer and instant — the graph records one activity per proposal
  28. 2026-06-04publicationPublication — backfill
  29. 2026-05-10revisionRevision 1
  30. 2026-05-10absenceSearched ClinicalTrials.gov for "3-HO-PCE dissociative hydroxyeticyclidine" — no results
  31. 2026-05-10absenceSearched Cross-reference for "3-HO-PCE vs 3-HO-PCP structural comparison pharmacology" — no results
  32. 2026-05-10absenceSearched ClinicalTrials.gov for "3-HO-PCE hydroxyeticyclidine dissociative" — no results
  33. 2026-05-10genGeneration — pipeline-v5 · with 3 morepipeline-v5
  34. 2026-05-10rungeneration run

The same entries, as forms: six forms.