25I-NBOH
4-iodo-2,5-dimethoxy-N-(2-hydroxybenzyl)phenethylamine
1Provenance card
the boundary, as counts
Sources
2927 with DOI
1 strong · 22 moderate · 6 weak
Compilations
12026-05-08T23:35:52.712Z
pipeline-v5 · prompt hash not recorded — run predates 2026-09
Decisions
28last ruled 2026-06-04
0 awaiting a ruling
Issued documents
62026-10-19T20:29:12.382Z
notice · info card · emergency
Searches
152 with no results
queries and counts on the build
Claims checked
7868 supported
68 supported · 10 not
Correspondence
0received
consent field ships in Phase 4
Edges
245
derivations recorded for this entity
Complete over 29 sources, 1 compilation, and 28 decisions.Not here: the private journal (never).Working material — drafts, discards, unsupported claims — is listed below and readable on the working page.Cite: psychedex.org/substances/25i-nboh/archive
Timeline
what happened, newest first — claims, searches and artifacts stay inside Build
- 2026-10-19issueIssued emergency
- 2026-10-19issueIssued info_card
- 2026-10-19issueIssued notice
- 2026-09-07src25CN-NBOH: A Selective Agonist for in vitro and in vivo Investigations of the Serotonin 2A Receptor
- 2026-09-07srcCharacterization of the hepatic cytochrome P450 enzymes involved in the metabolism of 25I-NBOMe and 25I-NBOH
- 2026-09-07srcIdentification of thermolabile positional isomers of N-(2-hydroxybenzyl)-2-(dimethoxyphenyl)ethanamines (NBOH series) using chromatography and mass spectrometry methods
- 2026-09-07srcThe Selective 5HT2A Receptor Agonist, 25CN-NBOH Exerts Excitatory and Inhibitory Cellular Actions on Mouse Medial Prefrontal Cortical Neurons
- 2026-09-07srcPharmacology and Toxicology of N-Benzylphenethylamine (NBOMe) Hallucinogens
- 2026-09-07srcOpioid analgesic drugs and serotonin toxicity (syndrome): mechanisms, animal models, and links to clinical effects
- 2026-09-07srcSevere 25E-NBOH intoxication associated with MDPHP intake: a case report, metabolism study, and literature review
- 2026-09-07src25I-NBOH: a new potent serotonin 5-HT2A receptor agonist identified in blotter paper seizures in Brazil
- 2026-09-07srcNeurochemical pharmacology of psychoactive substituted N-benzylphenethylamines: High potency agonists at 5-HT2A receptors.
- 2026-09-07srcThe selective 5-HT2A receptor agonist 25CN-NBOH: Structure-activity relationship, in vivo pharmacology, and in vitro and ex vivo binding characteristics
- 2026-09-07srcIdentification of psychedelic new psychoactive substances (NPS) showing biased agonism at the 5-HT2AR through simultaneous use of β-arrestin 2 and miniGαq bioassays
- 2026-09-07srcPostmortem detection of 25I-NBOMe in fluids and tissues determined by HPLC-MS/MS from a traumatic death
- 2026-09-07srcSimultaneous analysis of 2Cs, 25-NBOHs, 25-NBOMes and LSD in seized exhibits using liquid chromatography-tandem mass spectrometry: A targeted approach
- 2026-09-07srcCorrelation between the potency of hallucinogens in the mouse head-twitch response assay and their behavioral and subjective effects in other species
- 2026-09-07srcDiscovery of β-Arrestin-Biased 25CN-NBOH-Derived 5-HT2A Receptor Agonists
- 2026-09-07srcInvestigation of the 2,5-Dimethoxy Motif in Phenethylamine Serotonin 2A Receptor Agonists
- 2026-09-07srcStructure-Activity Assessment and In-Depth Analysis of Biased Agonism in a Set of Phenylalkylamine 5-HT2A Receptor Agonists.
- 2026-09-07srcN-Benzyl-5-methoxytryptamines as Potent Serotonin 5-HT2 Receptor Family Agonists and Comparison with a Series of Phenethylamine Analogues
- 2026-09-07srcIdentification of 5-HT2A receptor signaling pathways associated with psychedelic potential
- 2026-09-07srcBehavioral arrest and a characteristic slow waveform are hallmark responses to selective 5-HT2A receptor activation
- 2026-09-07srcBad trip due to 25I-NBOMe: a case report from the EU project SPICE II plus
- 2026-09-07src2-(4-Iodo-2,5-dimethoxyphenyl)-N-[(2-methoxyphenyl)methyl]ethanamine (25I-NBOME): A Harmful Hallucinogen Review
- 2026-09-07srcFatal Intoxications with 25B-NBOMe and 25I-NBOMe in Indiana During 2014.
- 2026-09-07srcA Case Review of the First Analytically Confirmed 25I-NBOMe-Related Death in Washington State
- 2026-09-07srcNBOMes-Highly Potent and Toxic Alternatives of LSD
- 2026-09-07srcAcute Effects of the Psychedelic Phenethylamine 25I-NBOMe in C57BL/6J Male Mice
- 2026-09-07srcPsilocin, the Psychoactive Metabolite of Psilocybin, Modulates Select Neuroimmune Functions of Microglial Cells in a 5-HT2 Receptor-Dependent Manner
- 2026-09-07srcMolecular interaction of serotonin 5-HT2A receptor residues Phe339(6.51) and Phe340(6.52) with superpotent N-benzyl phenethylamine agonists
- 2026-09-07src25I-NBOH Legal Status - Erowid NBOMe Series Vault
- 2026-09-04issueIssued emergency
- 2026-09-04issueIssued info_card
- 2026-09-04issueIssued notice
- 2026-06-04proposal26 value proposals approved togetherone review action inferred from a shared reviewer and instant — the graph records one activity per proposal
- 2026-06-04publicationPublication — backfill
- 2026-05-08revisionRevision 1
- 2026-05-08absenceSearched DEA press release / Federal Register for "DEA scheduling NBOMe NBOH synthetic phenethylamine" — no results
- 2026-05-08absenceSearched ClinicalTrials.gov for "25I-NBOH NBOH psychedelic" — no results
- 2026-05-08genGeneration — pipeline-v5 · with 3 morepipeline-v5
- 2026-05-08rungeneration run
The same entries, as forms: six forms.