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Psychedex

25E-NBOMe

4-ethyl-2,5-dimethoxy-N-(2-methoxybenzyl)phenethylamine

1Provenance card

the boundary, as counts

Sources

2321 with DOI

3 strong · 16 moderate · 4 weak

Compilations

12026-05-08T19:14:20.227Z

pipeline-v5 · prompt hash not recorded — run predates 2026-09

Decisions

45last ruled 2026-06-04

0 awaiting a ruling

Issued documents

62026-10-19T20:29:11.077Z

notice · info card · emergency

Searches

191 with no results

queries and counts on the build

Claims checked

8462 supported

62 supported · 22 not

Correspondence

0received

consent field ships in Phase 4

Edges

272

derivations recorded for this entity

Complete over 23 sources, 1 compilation, and 45 decisions.Not here: the private journal (never).Working material — drafts, discards, unsupported claims — is listed below and readable on the working page.Cite: psychedex.org/substances/25e-nbome/archive

Timeline

what happened, newest first — claims, searches and artifacts stay inside Build

  1. 2026-10-19issueIssued emergency
  2. 2026-10-19issueIssued info_card
  3. 2026-10-19issueIssued notice
  4. 2026-09-07srcAnalytical characterization of three hallucinogenic N-(2-methoxy)benzyl derivatives of the 2C-series of phenethylamine drugs.
  5. 2026-09-07srcIn vitro phase I metabolism of three phenethylamines 25D-NBOMe, 25E-NBOMe and 25N-NBOMe using microsomal and microbial models.
  6. 2026-09-07srcMultimodal imaging of hallucinogens 25C- and 25I-NBOMe on blotter papers.
  7. 2026-09-07srcPharmacology and Toxicology of N-Benzylphenethylamine (NBOMe) Hallucinogens
  8. 2026-09-07srcDesigner drugs: mechanism of action and adverse effects
  9. 2026-09-07srcThe novel psychoactive substance 25E-NBOMe induces reward-related behaviors via dopamine D1 receptor signaling in male rodents.
  10. 2026-09-07srcHallucinogen-Like Action of the Novel Designer Drug 25I-NBOMe and Its Effect on Cortical Neurotransmitters in Rats
  11. 2026-09-07srcNeurochemical and Behavioral Effects of a New Hallucinogenic Compound 25B-NBOMe in Rats.
  12. 2026-09-07srcNeurochemical pharmacology of psychoactive substituted N-benzylphenethylamines: High potency agonists at 5-HT2A receptors.
  13. 2026-09-07srcEffects of the hallucinogen 2,5-dimethoxy-4-iodophenethylamine (2C-I) and superpotent N-benzyl derivatives on the head twitch response
  14. 2026-09-07srcReceptor interaction profiles of novel N-2-methoxybenzyl (NBOMe) derivatives of 2,5-dimethoxy-substituted phenethylamines (2C drugs)
  15. 2026-09-07srcComparative neuropharmacology of N-(2-methoxybenzyl)-2,5-dimethoxyphenethylamine (NBOMe) hallucinogens and their 2C counterparts in male rats
  16. 2026-09-07srcCorrelation between the potency of hallucinogens in the mouse head-twitch response assay and their behavioral and subjective effects in other species
  17. 2026-09-07srcTolerance and Cross-Tolerance among Psychedelic and Nonpsychedelic 5-HT2A Receptor Agonists in Mice
  18. 2026-09-07src25X-NBOMe compounds - chemistry, pharmacology and toxicology. A comprehensive review.
  19. 2026-09-07srcFatal Intoxications with 25B-NBOMe and 25I-NBOMe in Indiana During 2014.
  20. 2026-09-07srcGas Chromatography-Mass Spectrometry Method for the Quantitative Identification of 23 New Psychoactive Substances in Blood and Urine
  21. 2026-09-07srcPrevalence of use and acute toxicity associated with the use of NBOMe drugs
  22. 2026-09-07srcCase series: toxicity from 25B-NBOMe--a cluster of N-bomb cases.
  23. 2026-09-07srcNBOMes-Highly Potent and Toxic Alternatives of LSD
  24. 2026-09-07srcElectrochemical Simulation of 25B-NBOMe Phase I Metabolism and Metabolite Profiling by HPLC-QTOF-MS.
  25. 2026-09-07srcSchedules of Controlled Substances: Placement of Three Synthetic Phenethylamines Into Schedule I
  26. 2026-09-07srcNBOMe Compounds Legal Status
  27. 2026-09-04issueIssued emergency
  28. 2026-09-04issueIssued info_card
  29. 2026-09-04issueIssued notice
  30. 2026-06-04proposal43 value proposals approved togetherone review action inferred from a shared reviewer and instant — the graph records one activity per proposal
  31. 2026-06-04publicationPublication — backfill
  32. 2026-05-08revisionRevision 1
  33. 2026-05-08absenceSearched ClinicalTrials.gov for "25E-NBOMe NBOMe psychedelic" — no results
  34. 2026-05-08genGeneration — pipeline-v5 · with 4 morepipeline-v5
  35. 2026-05-08rungeneration run

The same entries, as forms: six forms.