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Psychedex
Facts label

THCV Facts

Cannabinoid; Cannabinoid; Cannabinoid CB1 receptor partial agonist

Dose and durationby route · individual sensitivity varies

Oral(mg)
Thresholdnot recordedLightnot recordedCommon5 – 5 mgStrongnot recordedHeavynot recorded

Starts in 90 – 180 minLasts 6 – 12 hours

Body and dependence

Acute toxicity
Negligible
Chronic toxicity
Negligible
Physical dependence
None
Psychological dependence
Negligible
Withdrawal
None recorded
Compulsive redosing
Negligible

Tolerance

Builds
None
Fully resets after
Not recorded
Carries over to
Δ9-THC

Effectslikely at a common dose

Body
none likely · 6 possible, including Insomnia
Thinking
none likely · 1 possible
Feeling
none likely · 2 possible
Awareness
none likely · 1 possible

Who shouldn't take it

Absolute
Pregnancy and lactation
Relative
History of psychotic illness; Significant hepatic impairment; Concurrent insulin or sulfonylurea therapy; Narrow therapeutic index CYP2C9/CYP3A4 substrates

Combinations60 recorded

Dangerous (11)
Ketamine, DXM, PCP; Opioids; GHB, Baclofen; GHB, GBL; Ibogaine; Local anesthetics; MAOIs; NDRIs (Wellbutrin); Salvia, Ibogaine; SNRIs; Synthetic cannabinoids
Caution (33)
See full page: psychedex.org/substances/thcv
Not graded (16)
Not listed never means safe.

Seek help immediately if

Natural cannabis rarely causes a medical emergency — "greening out" is: pale/sweaty skin, dizziness, nausea or vomiting, anxiety or panic, rapid heartbeat, feeling faint — and usually passes with rest.

Seek emergency help for these — far more likely with synthetic cannabinoids ("spice" / K2):

  • Seizures
  • Severe chest pain; very fast or irregular heartbeat
  • Unresponsiveness or extreme drowsiness
  • Severe agitation, aggression, or psychosis
  • Repeated vomiting; difficulty breathing

What to do

  1. Sit or lie them down somewhere calm, cool, and quiet
  2. Reassure them — cannabis panic and "greening out" pass with time
  3. Offer sips of water; a little sugar can help if they feel faint
  4. Recovery position if nauseated, drowsy, or vomiting
  5. Stay with them and monitor
  6. For seizures, chest pain, unresponsiveness, or severe agitation, call emergency services

Natural cannabis "greening out" resolves with rest, calm, and time, with no lasting harm. Synthetic cannabinoids are unpredictable and can cause seizures, cardiac events, kidney injury, and severe agitation that needs emergency care.

988 Suicide & Crisis LifelineFireside Project: 62-FIRESIDE

psychedex.org/substances/thcv · Version r1 · Not medical adviceValues as of
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