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Salvinorin A Facts

Hallucinogen; Salvinorin; Kappa-opioid receptor agonist

Dose and durationby route · individual sensitivity varies

Sublingual

No dose recorded for this route. The timings are not a dose guide.

Starts in 10 – 20 minLasts 30 – 90 minAfter-effects 30 – 120 min

Also recorded: Smoked. See full page: psychedex.org/substances/salvinorin-a

Body and dependence

Acute toxicity
Low
Chronic toxicity
Low
Physical dependence
None
Psychological dependence
Negligible
Withdrawal
None recorded
Compulsive redosing
Negligible

Tolerance

Builds
Rapid
Fully resets after
Not recorded
Carries over to
dynorphin; U50488; pentazocine

Effectslikely at a common dose

Perception
Depth perception distortion; Holotropic state; Perspective distortion; Proprioceptive distortion; Sensory deprivation; Spatial disorientation; +14 possible, including Vestibular distortion, Visual haze / noise
Body
Body schema distortion; Dizziness; Motor control impairment; +17 possible, including Nausea, Heart rate perception changes, Trembling
Thinking
Cognitive impairment; Confusion; Decision impairment; Focus suppression; Immersion enhancement; Information processing suppression; Language suppression; Memory suppression; Thought disorganization; +13 possible, including Analysis suppression, Cognitive dysphoria, Thought loops
Feeling
none likely · 6 possible, including Anxiety, Dysphoria, Paranoia
Self
Communication suppression; Depersonalization; Derealization; +4 possible, including Social disconnection
Time
Temporal disorientation; Time alteration; +1 possible

Who shouldn't take it

Absolute
Psychotic disorders (schizophrenia, schizoaffective disorder); Unsupervised use or hazardous environments; Vehicle operation
Relative
Bipolar disorder; Concurrent opioid agonist use

Combinations60 recorded

Dangerous (35)
Ketamine, DXM, PCP; Opioids; 5-HTP, Tryptophan; Alpha-2 adrenergic receptor antagonist; Amphetamines; Anticholinergics; Antipsychotics; Atypical antipsychotics; Buspirone; Cannabis; Cannabis, THC; CBD; Dopamine agonists; DXM; Ephedrine, Pseudoephedrine; GHB, Baclofen; GHB, GBL; Lithium; Local anesthetics; MAOIs; MDMA, Amphetamines; MDMA, MDA; NDRIs (Wellbutrin); NRIs; and 11 more, see full page
Caution (18)
See full page: psychedex.org/substances/salvinorin-a
Not graded (7)
Not listed never means safe.

Seek help immediately if

No emergency profile is recorded for this substance. Not recorded never means no risk.

988 Suicide & Crisis LifelineFireside Project: 62-FIRESIDE

psychedex.org/substances/salvinorin-a · Version r1.a1 · Not medical adviceValues as of
On the printout